Am J Transplant, Volume 5, Suppl 3 Archives - Page 25 of 170 - ATC Abstracts

2015 American Transplant Congress
Risk of ESRD Attributable to Live Kidney Donation in Various Subgroups of Donors
A. Muzaale, A. Massie, D. Segev.
Johns Hopkins University, Baltimore, MD.
Risk of ESRD attributable to live donation in male, older, obese, related donors, and donors with high predonation eGFR remains uncharacterized.Methods: Various subgroups of individuals…
2015 American Transplant Congress
Interleukin-1 Receptor Signaling by Graft Stromal Cells Regulates Donor-Reactive CD8 T Cell Responses to Cardiac Allografts
S. Iida,¹ D. Kish,¹ R. Abe,² K. Tanabe,³ W. Baldwin,¹ R. Fairchild.¹
¹Immunology, Cleveland Clinic, Cleveland, OH; ²Immunology, Science University of Tokyo, Chiba, Japan; ³Urology, Tokyo Women's Medical University, Tokyo, Japan.
Allograft reperfusion induces inflammation that directs the infiltration of memory T cells into the allograft and their activation to express functions mediating graft injury. The…
2015 American Transplant Congress
Educating Hispanic ESRD Patients About Living Donation: Impact of a Brief Intervention
E. Alvaro, J. Siegel, J. Poulsen, E. O'Brien.
Psychology, Claremont Graduate University, Claremont, CA; Psychology, Claremont Graduate University, Claremont, CA; Transplantation, St. Vincent Medical Center, Los Angeles, CA; Psychology, Claremont Graduate University, Claremont, CA.
Purpose: This study was designed to enhance Hispanic ESRD patient knowledge, norm perceptions, and efficacy regarding discussions of living kidney donation.Methods: The study was a…
2015 American Transplant Congress
Notch-1 Inhibition Promotes Immune Regulation in Solid Organ Transplantation
C. Magee,¹ M. Ohari,¹ T. Shimizu,¹ S. Ohori,¹ N. Najafian,² L. Riella.¹
¹Transplantation Research Center, Brigham and Women's Hospital, Harvard Medical School, Boston; ²Cleveland Clinic, Weston.
Notch receptor signaling plays a key role in T cell activation and differentiation, though limited data exist on its importance in immune regulation. Herein, we…
2015 American Transplant Congress
Inverse Monocytic Subset Profile in Blood and Tissue During Heart Transplant Rejection
T. van den Bosch,¹ M. Kraaij,¹ K. Caliskan,² A. Constantinescu,² O. Manintveld,² P. Leenen,³ C. Baan,¹ M. van Groningen,⁴ A. Rowshani.¹
¹Department of Internal Medicine, Section Nephrology and Transplantation, Erasmus Medical Center, Rotterdam, Netherlands; ²Department of Cardiology, Erasmus Medical Center, Rotterdam, Netherlands; ³Department of Immunology, Erasmus Medical Center, Rotterdam, Netherlands; ⁴Department of Pathology, Erasmus Medical Center, Rotterdam, Netherlands.
Introduction: Increased monocytic infiltration of heart transplant tissue is documented during acute rejection. It is still unclear how changes in circulating monocyte pool relate to…
2015 American Transplant Congress
Evaluation of the Gastrointestinal Tract as a Potential Route of Primary Polyomavirus Infection
G. Huang,¹ G. Zeng,² Y. Huang,² P. Randhawa.²
¹Department of Organ Transplantation, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China; ²Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA.
Detection of Polyomavirus(Py) DNA in metropolitan river water worldwide has led to the suggestion that primary viral infection can occur by the oral route. The…
2015 American Transplant Congress
Proximal Tubular Dysfunction Is Common After the First Year of Kidney Transplantation
G. Ensergueix,¹ J. Allard,¹ F. Saint-Marcoux,² B. Marin,³ S. Bodeau,² J.-C. Aldigier,¹ P. Marquet,² M. Essig.¹
¹Nephrology, Dialysis, Transplantation, University Hospital, Limoges, France; ²Pharmacology, Toxicology, University Hospital, Limoges, France; ³Epidemiology, Biostatistics, Methodology, University Hospital, Limoges, France.
Background: After the initial period of kidney transplantation, the prevalence of proximal tubular dysfunction (PTD) and its consequences are unknown. The aim of this study…
2015 American Transplant Congress
The Outcomes of Second Transplantation in Recurrent IgA Nephropathy
C. Baek,¹ H. Kim,¹ W. Yang,¹ W. Huh,² Y. Kim,³ J. Yang,⁴ D. Han,⁵ S.-K. Park.¹
¹Department of Internal Medicine, Asan Medical Center, Seoul, Republic of Korea; ²Department of Medicine, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea; ³Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea; ⁴Transplantation Center, Seoul National University Hospital, Seoul, Republic of Korea; ⁵Department of Surgery, Asan Medical Center, Seoul, Republic of Korea.
BackgroundRecurrence of original glomerulonephritis is an important cause of graft loss. In some studies, histologic recurrence of IgA nephropathy (IgAN) occurs in 60% after 1st…
2015 American Transplant Congress
A 10 Min “No-Touch” Time – Is It Enough in DCD? A DCD Animal Study
M. Sereinigg,¹ V. Stadlbauer,² T. Seifert-Held,³ F. Iberer,¹ P. Stiegler.¹
¹Department for Transplant Surgery, Medical University Graz, Graz, Austria; ²Department for Gastroenterology and Hepatology, Medical University Graz, Graz, Austria; ³Department for Neurology, Medical University Graz, Graz, Austria.
Introduction: DCD is under investigation due to the lack of human donor organs. Required times of cardiac arrest vary between 75 seconds and 27 min…
2015 American Transplant Congress
Detection of Donor Specific HLA-Ab (DSA) Against Native HLA Molecules Expressed On Donor Cell Surface to Eliminate False Positive DSA in Luminex Single Antigen Beads (LMX-SAB)
G. Chen, L. Lin, D. Tyan.
Pathology, Stanford University, Palo Alto, CA.
Introduction:The LMX-SAB has been extensively used for DSA virtual crossmatch (VXM) to predict actual crossmatch (AXM). The extreme pH and harsh chemical reaction conditions used…