ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Excellent Outcomes With Deceased Donor Kidney Transplants With a Terminal Creatinine >= 3

    L. Matsuoka,1 E. Alicuben,1 K. Woo,1 H. Shidban,1 Y. Qazi,2 M. Smogorzewski,2 S. Alexopoulos.1

    1Department of Surgery, USC Keck School of Medicine, Los Angeles, CA; 2Department of Nephrology, USC Keck School of Medicine, Los Angeles, CA.

    Purpose: Kidneys from deceased donors with elevated creatinine are frequently discarded due to concerns about poor post-transplant outcomes. In this study we sought to determine…
  • 2015 American Transplant Congress

    Liver Allograft Utilization Within the United States: 2003-2013

    J. Renz,1 G. Diaz,1 L. Ratner,2 H. Yersiz,3 M. Millis,1 J. Matthews.1

    1Department of Surgery, University of Chicago, Chicago, IL; 2Department of Anesthesia/Critical Care, University of Chicago, Chicago, IL; 3Department of Surgery, Columbia University, New York, NY; 4Department of Surgery, University of California Los Angeles, Los Angeles, CA.

    Objectives: 1) Evaluate liver allograft availability, utilization, and failure probability utilizing the liver donor risk index(LDRI) 2) Correlate allograft utilization with waitlist mortality and incidence…
  • 2015 American Transplant Congress

    Hypothermic Machine Preservation Reduces Inflammatory, Hypoxic and Apoptotic Injuries in Human Liver Transplantation

    J. Guarrera, C. Bae, S. Henry.

    Center for Liver Disease and Transplantation, Columbia University Medical Center, New York, NY.

    Introduction: Hypothermic machine perfusion (HMP) is in its infancy in Liver Transplantation. We analyzed all molecular samples from our cumulative clinical experience at Columbia University.Methods:…
  • 2015 American Transplant Congress

    Interim Results of a Phase 1 Trial of Treg Adoptive Cell Transfer (TRACT) in Living Donor Kidney Transplant Recipients

    J. Leventhal,1 A. LeFever,2 A. Skaro,1 L. Gallon,1 J. Mathew,1 D. Stare,1 I. Konieczna,1 J. He,1 G. Johnson.3

    1Northwestern University, Chicago; 2Northwestern Memorial Hospital, Chicago; 3TRACT Therapeutics Inc., Chicago.

    Therapeutic cell transfer using regulatory T cells (Tregs) in transplant recipients may reduce the need for drug based immunosuppression (IS) and improve long term graft…
  • 2015 American Transplant Congress

    Glucose Chemical Exchange Saturation Transfer MRI of Acute Renal Allograft Rejection

    D. Kentrup,1 A. Busch,2 H. Pawelski,1 V. Hoerr,2,3 S. Reuter.1

    1Department of Medicine D, University Hospital Münster, Münster, Germany; 2Department of Clinical Radiology, University Hospital Münster, Münster, Germany; 3Institute of Medical Microbiology, Jena University Hospital, Jena, Germany.

    Purpose: During acute rejection episodes large amounts of immune cells infiltrate renal grafts, leading to inflammation accompanied by an increased glucose metabolism.Given these circumstances we…
  • 2015 American Transplant Congress

    Evaluation of the Use of Leflunomide for the Prevention of BK Nephropathy in Renal Transplant Recipients- A Single Center Experience

    S. Jonchhe, E. Hollinger, S. Jensik, O. Olaitan, A. Hodowanec, M. Hertl, S. Fayek, E. Chan, C. Pullum, N. Alvey.

    Rush University Medical Center, Chicago, IL.

    Objective: The purpose of this study was to compare the efficacy of leflunomide in combination with reduced immunosuppression versus reduction of immunosuppression alone for the…
  • 2015 American Transplant Congress

    Superior Outcomes of Kidney Transplantation Compared With Dialysis in Korea: A Propensity–Matched Analysis of a National Population-Based Cohort Study Between 2005 and 2008

    K. Yoo,1 C. Kim,2 J. Lee,3 M.-H. Kim,4 H. Cho,1 K. Kim,5 H. Kim,6 D.-R. Ryu,7 D. Kim,1 C. Lim,8 Y. Kim,1 J. Lee.8

    1Internal Medicine, Seoul National University Hospital, Seoul, Korea; 2School of Public Health, Seoul National University, Seoul, Korea; 3Internal Medicine, Hallym University Hangang Sacred Heart Hospital, Seoul, Korea; 4Dental Hygiene, College of Health Science, Eulji University, Daejeon, Korea; 5Public Health, Graduate School, Korea University, Seoul, Korea; 6Internal Medicine, Wonkwang University College of Medicine Sanbon Hospital, Sanbon, Korea; 7Internal Medicine, Ewha Womans University Hospital, Seoul, Korea; 8Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea.

    Background: Kidney transplantation (KT) can improve clinical outcomes in patients with end-stage renal disease. However, the data about KT outcome comparing with dialysis is rare…
  • 2015 American Transplant Congress

    Anti-Apoptotic But Not Mitotic Effects of 3,3',5-triiodo-l-thyronine in the Liver of Brain Dead Rats

    A. van Erp,1 R. Rebolledo,2 J. Wiersema-Buist,1 P. Ottens,1 H. Leuvenink,1 P. Romanque.2

    1Department of Surgery, University Medical Center Groningen, Groningen, Netherlands; 2Department of Surgery, University of Chile, Santiago, Chile.

    Thyroid hormone treatment in brain dead organ donors has been extensively studied and applied in the clinical setting. However, its effectiveness remains controversial due to…
  • 2015 American Transplant Congress

    Transport Perfusion Fluid Analysis from Deceased Donor Kidney Transplants (DD KT) and Pancreas Transplants (SPK; PAK; PTA)

    C. Taylor, Y. Tabbakh, C. van Nispen tot Pannerden, D. Yershov, F. Calder, C. Callaghan, M. Drage, N. Karydis, N. Kessaris, I. Loukopoulos, N. Mamode, J. Olsburgh.

    Renal and Transplant, Guys Hospital, London, United Kingdom.

    INTRODUCTION: Candida cultured in transplant perfusion fluid (TPF) may have adverse consequences (Mai 2006). TPF culture rates, frequency of positive culture results and associated clinical…
  • 2015 American Transplant Congress

    Chronic Active Antibody Mediated Rejection (cABMR): Treatment, Outcomes and Predictors of Graft Loss in a Large Case Series

    R. Redfield,1 T. Ellis,1 W. Zhong,1 T. Zens,1 M. Rizzari,1 J. Scalea,1 L. Jacobson,1 D. Mandelbrot,1 S. Parajuli,1 B. Muth,1 M. Mohamed,1 S. Panzer,1 B. Astor,1 M. Samaniego,2 D. Kaufman,1 A. Djamali.1

    1University of Wisconsin, Madison, WI; 2University of Michigan, Ann Arbor, MI.

    Background: CABMR is a barrier to long-term kidney allograft survival. There is little information on the treatment and outcomes of kidney transplant recipients with cABMR.Methods:…
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