Am J Transplant, Volume 5, Suppl 3 Archives - Page 21 of 170 - ATC Abstracts

2015 American Transplant Congress
Everolimus Plus Reduced-Exposure Calcineurin Inhibitor Versus Mycophenolate Mofetil Plus Standard-Exposure Calcineurin Inhibitor: 2-Year Results in Living Donor Kidney Transplant Recipients
Y. Watarai,¹ N. Akutsu,² K. Saito,³ Y. Nakagawa,³ O. Kamisawa,⁴ T. Kenmochi.⁵
¹Transplant Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan; ²Surgery, Chiba-East Hospital, Chiba, Japan; ³Urology, Niigata University, Niigata, Japan; ⁴Medical Division, Novartis Pharma K.K., Tokyo, Japan; ⁵Transplant Surgery, Fujita Health University, Toyoake, Japan.
Purpose: To evaluate the long-term efficacy and safety of everolimus (EVR) plus reduced cyclosporine (rCsA) compared to mycophenolate mofetil (MMF) plus standard cyclosporine at 24…
2015 American Transplant Congress
Safety and Efficacy of Low Dose and Very Low Dose Extended-Release Tacrolimus / MMF in De Novo Kidney Transplant Recipients
Y. Watarai,¹ M. Okada,¹ K. Futamura,¹ K. Ito,¹ T. Yamamoto,¹ M. Tsujita,¹ T. Hiramitsu,¹ N. Goto,¹ S. Narumi,¹ T. Kobayashi.²
¹Transplant Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan; ²Applied Immunology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Recently, once-daily tacrolimus extended-release formulation (TACER) has been accepted in kidney transplantation, however its optimal dosing are not well evaluated. We have validated low dose…
2015 American Transplant Congress
Histological Analysis in ABO-Compatible and Incompatible Kidney Transplantation By Performing 3-Month and 1-Year Protocol Biopsies
K. Masutani,¹ A. Tsuchimoto,¹ Y. Matsukuma,¹ K. Kurihara,² Y. Okabe,² H. Kitada,² M. Tanaka,² T. Kitazono,¹ K. Tsuruya.¹
¹Department of Medicine and Clinical Science, Kyushu University, Fukuoka, Japan; ²Department of Surgery and Oncology, Kyushu University, Fukuoka, Japan.
Background. ABO incompatible kidney transplantation (ABO-I KTx) is nowadays a well-established procedure to expand living donor source. Graft and patient survivals of ABO-I KTx were…
2015 American Transplant Congress
Outcomes of Patients With Hepatocellular Carcinoma Receiving a Donation After Cardiac Death Liver Graft
W. Goldkamp,¹ J. Vanatta,^2,3 S. Nair,^2,3 E. Wong,³ N. Dbouk.^2,3
¹Internal Medicine, The Universty of Tennessee Health Science Center, Memphis, TN; ²Surgery, The Universty of Tennessee Health Science Center, Memphis, TN; ³Methodist Universty Hospital Transplant Institute, Memphis, TN.
Background: Recent data suggests that patients with Hepatocellular carcinoma (HCC) who receive a donation after cardiac death (DCD) graft have inferior graft and patient survival…
2015 American Transplant Congress
Does Higher Cost Improve Outcome in Pediatric Liver Transplantation?
J. Minneman, J. Grijalva, S. Rangel, H. Kim, K. Vakili.
Surgery, Boston Children's Hospital, Boston, MA.
Examine the relationship between transplant-related total cost and 1-year graft failure and patient mortality rate for liver transplantation at freestanding children's hospitals.Using the Pediatric Health…
2015 American Transplant Congress
New Insights in Clinical and Genetic Determinants of Longitudinal Dose-Corrected CNI Exposure in Children After Renal Transplantation
N. Knops,¹ M. van Dyck,¹ E. Levtchenko,¹ D. Kuypers,² J. Herman.¹
¹Pediatric Nephrology and Solid Organ Transplantation, University Hospitals Leuven, Leuven, Belgium; ²Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium.
Purpose: Calcineurin-inhibitors (CNI) have a narrow therapeutic index and dosing is difficult due to inter- and intra-individual variation in pharmacokinetics (PK). Polymorphisms in genes involved…
2015 American Transplant Congress
Living Donor Transplant Rates in Children Are Declining
D. Keith, A. Nishio Lucar, G. Vranic.
University of Virginia, Charlottesville, VA.
Living donor (LD) transplant rates have been declining since 2004 in adult candidates. We sought to determine if this trend is also occurring in pediatric…
2015 American Transplant Congress
The Explore Transplant Program in GA: Is Historical Access to Transplantation Associated With Kidney Transplant Knowledge and Preparedness to Educate ERSD Patients?
J. Gander,¹ C. Isenhour,¹ L. McPherson,¹ M. Basu,¹ B. Tao,¹ K. Smtih,¹ S. Pastan,¹ A. Waterman,² R. Patzer.¹
¹Emory University, Atlanta; ²University of California, Los Angeles.
IntroductionDialysis facilities play a key role in educating end stage renal disease patients on kidney transplantation (KTx). We aimed to investigate the association between historical…
2015 American Transplant Congress
Can Gene-Expression Profiling Score Help Explain the Adverse Clinical Outcomes Seen in Gender-Mismatched Heart Transplants?
N. Sulemanjee,¹ P. Prasad,² T. Wolf,² V. Thohan,¹ J. Teuteberg.³
¹Aurora Research Institute, St. Luke's Medical Center, Milwaukee, WI; ²CareDx, Inc., Brisbane, CA; ³University of Pittsburgh Medical Center, Pittsburgh, PA.
Background: Gene-expression profiling (GEP) testing, in conjunction with clinical assessment, is an established laboratory test intended to aid in the identification of acute cellular rejection…
2015 American Transplant Congress
Boosting the Adaptive Immune Response Prevents the High Incidence of Herpes Zoster After Lung or Heart Transplantation
N. van Besouw,¹ S. Roest,² J. Zuijderwijk,¹ R. de Kuiper,¹ J. van Weezel,³ A. van der Eijk,⁴ W. Weimar,¹ P. Hal,³ O. Manintveld.²
¹Internal Medicine - Transplantation, Erasmus MC, Rotterdam, Netherlands; ²Cardiology, Erasmus MC, Rotterdam, Netherlands; ³Respiratory Medicine, Erasmus MC, Rotterdam, Netherlands; ⁴Viroscience, Erasmus MC, Rotterdam, Netherlands.
Purpose Primary varicella zoster virus (VZV) infection causes varicella and lifelong latent infection in ganglia from which it may reactivate leading to herpes zoster (HZ).…