Am J Transplant, Volume 5, Suppl 3 Archives - Page 20 of 170 - ATC Abstracts

2015 American Transplant Congress
Divergence in Risk Factors for Graft Loss and Death Across Race May Mediate Kidney Transplant Outcome Disparity
M. Posadas Salas,¹ D. Taber,² M. Kamel,¹ M. Kadian,¹ M. Salazar,¹ P. Mohan,¹ T. Srinivas.¹
¹Department of Medicine, Medical University of South Carolina, Charleston, SC; ²Department of Surgery, Medical University of South Carolina, Charleston, SC.
Differences in outcomes between African American and non-African American kidney transplant recipients may reflect disparate access to health care. Minimizing this disparity demands a deeper…
2015 American Transplant Congress
Effect of Distinct Immunosuppressive Protocols On the Profile of Cytokines Expression in Renal Transplant Recipients of Extended Criteria Donor Kidneys
C. Montoro Mazeti,¹ C. Zangrossi Dezotti,¹ I. Fernandes-Charpiot,^1,2 H. Caldas,¹ M. Baptista,^1,2 M. Abbud Filho.^1,2,3
¹Laboratory of Immunology and Experimental Transplantation, Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto, SP, Brazil; ²Department of Medicine, Division of Nephrology, Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto, SP, Brazil; ³Urology and Nephrology Institute, Urology and Nephrology Institute, Sao Jose do Rio Preto, SP, Brazil.
Background: Transplant recipients (RTx) of kidneys classified as extended criteria (ECD) seems to have worst outcomes when compared with RTx of standard kidneys (SCD) and…
2015 American Transplant Congress
Hepatic Stellate Cells Inhibit T Cells Through Active TGFβ1 from a Cell-Surface-Bound Latent TGFβ1/GARP Complex
Y. Li, B.-G. Kim, S. Qian, J. Letterio, J. Fung, L. Lu, F. Lin.
Immunology, Lerner Research Institute, Cleveland Clinic; 2Pediatric Hematology-Oncology, Case Western Reserve University; 3General Surgery, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH.
Nonparenchymal cells appear to be critical to maintain the immunoprivileged status of liver as whole liver allografts are well-tolerated in mice, but allo-hepatocytes are rapidly…
2015 American Transplant Congress
Phenotype of Renal Tubular Cell Death During Delayed Graft Function
S. Jain,¹ R. Plenter,¹ T. Nydam,¹ C. Ruller,¹ C. Edelstein,^1,2 A. Jani.^1,2
¹University of Colorado, Aurora, CO; ²Veterans Affairs Medical Center, Denver, CO.
Background: Delayed graft function (DGF) independently predicts reduced 5 yr kidney transplant survival. Treatments of DGF are lacking. Cold ischemia (CI) is a significant risk…
2015 American Transplant Congress
Calcineurin-Inhibitor Conversion to mTOR Inhibitor in Renal Transplant Recipients Leads to Worse Long Term Clinical Outcomes
A. Alvarado,¹ A. Shetty,¹ O. Traitanon,¹ J. Leventhal,¹ V. Mas,² D. Chhabra,³ J. Matthews,¹ L. Gallon.¹
¹Comprehensive Transplant Center, Northwestern University, Chicago, IL; ²University of Virgina, Charlottesville, Va; ³Advocate Christ Medical Center, Chicago, IL.
We previously reported the short-term feasibility of Calcineurin-Inhibitor (CNI) elimination in kidney transplant recipients. We now report the long-term clinical impact on renal allograft function…
2015 American Transplant Congress
NFAT Regulated Cytokine Gene Expression for Immune Monitoring in Kidney Transplant Recipients
V. Tatapudi, A. Webber, C. Leung, F. Vincenti.
Div. of Nephrology, Dept. of Medicine, University of California, San Francisco Medical Center, San Francisco, CA.
Purpose of Study:To demonstrate that profiling kidney transplant recipients (KTR) on Tacrolimus (Tac) based immunosuppression based on quantitative analysis of NFAT (nuclear factor of activated…
2015 American Transplant Congress
12-Month Athena Study: Everolimus Vs. Standard Regimen in De Novo Renal Transplant Recipients
C. Sommerer,¹ B. Suwelack,¹ D. Dragun,¹ I. Hauser,¹ P. Schenker,¹ D. Bäumer,² B. Nashan,¹ F. Thaiss.¹
¹Athena Study Group, Germany; ²Novartis, Pharma, Germany.
Background: Post-kidney transplant (KTx) long-term and full dose/standard calcineurin inhibitor (CNI) use is associated with an increased risk for malignancies, cardiovascular disease, and renal failure.…
2015 American Transplant Congress
The Clinical Outcome of Plasma Cell-Rich Rejection of Kidney Allograft
J. Hasegawa,¹ K. Honda,² S. Wakai,¹ H. Shirakawa,³ M. Okumi,³ K. Omoto,³ H. Ishida,³ K. Tanabe.³
¹Nephrology, Ohkubo Hospital, Tokyo, Japan; ²Pathology, Tokyo Women's Medical University, Tokyo, Japan; ³Urology, Tokyo Women's Medical University, Tokyo, Japan.
Background: Plasma cell-rich rejection (PCRR) is a rare type of allograft rejection characterized by the presence of mature plasma cells. This type of rejection has…
2015 American Transplant Congress
SBRT(Stereotactic Body Radiotherapy) to Bridge or Down-Size HCC for Liver Transplantation
N. Thai,¹ K. Tom,¹ M. Szramowski,¹ P. Abrams,¹ J. Oliva,³ D. Monga,⁴ M. Raj,⁴ D. Parda,² A. Kirichenko.²
¹Transplant Surgery, Allegheny Health Network, Pittsburgh, PA; ²Radiation Oncology, Allegheny Health Network, Pittsburgh, PA; ³Hepatology, Allegheny Health Network, Pittsburgh, PA; ⁴Medical Oncology, Allegheny Health Network, Pittsburgh, PA.
Twenty seven (27) pts with HCC and cirrhosis have been treated with SBRT with intent for liver transplantation since 2010 at Allegheny Health Network. Nineteen…
2015 American Transplant Congress
Severe Sarcopenia and Increased Fat Stores in Pediatric Patients With Liver, Kidney and Intestine Failure
W. Bush, C. Miller, C. Kubal, J. Fridell, A. Tector, R. Mangus.
Transplant Division, Dept of Surgery, Indiana University School of Medicine, Indianapolis, IN.
Background: Recent research suggests that measures of frailty, such as nutrition status, may be important predictors of surgical and transplant outcomes. The objectively calculated degree…