2015 American Transplant Congress
Validation of a Blood and Biopsy Gene Expression-Based Molecular Diagnostics for Subclinical Acute Rejection: Comparing DNA Microarrays Vs. Next-Generation RNA Sequencing
1The Scripps Research Institute, La Jolla, CA; 2Northwestern University, Chicago, IL.
Background: Microarray-based gene expression signatures for clinical diagnostics are well described. However, microarrays lack advantages offered by newer technologies such as Next Generation Sequencing (NGS):…2015 American Transplant Congress
Urinary Cell-Free DNA Is a Sensitive Marker of Early Renal Transplant Injury
Surgery, UC San Francisco, San Francisco, CA.
Introduction:Circulating donor-derived cell-free DNA (dd-cfDNA) has been reported as a surrogate of transplant injury in the blood but requires expensive donor and recipient DNA sequencing.Method:…2015 American Transplant Congress
Mononuclear Cell Infiltrates Characterization in Scar Tissue from a Bilateral Forearm Transplant Patient: Findings to Think
Herein we report the cell infiltrating pattern in scar tissue resected at the junction of the VCA and the tissue corresponding to the recipient arm,…2015 American Transplant Congress
The Predictive Value of the Proliferation Marker Ki-67 in Patients With Fulminant Hepatic Failure
This study aimed to evaluate the prognostic significance of the cellular proliferation marker Ki-67 in the liver biopsies of patients with fulminant hepatic failure.Under IRB…2015 American Transplant Congress
IgM+ Antigen Binding B Cells in Peripheral Blood Regulate IFNγ Production in Response to HLA Proteins
Chronic antibody mediated rejection (CAMR) is a major cause of graft loss in renal transplant recipients. Previous work utilising an IFNγ ELISPOT assay revealed two…2015 American Transplant Congress
Association Between the Timed Up and Go Test and Waitlisting for Kidney Transplantation
Introduction: The Timed Up and Go Test (TUGT) is a test of balance, mobility and functional capacity. Longer times on the TUGT are associated with…2015 American Transplant Congress
Kidney Transplantation from Expanded Criteria Deceased Donors With Terminal Acute Kidney Injury
We investigated clinical outcomes of kidney transplantation (KT) from deceased donors with terminal acute kidney injury (AKI) defined acute kidney injury network (AKIN) criteria and…2015 American Transplant Congress
Alemtuzumab Induction Is Associated With a Lower Risk of Early Rehospitalization After Kidney Transplant
Early rehospitalizations within the first 30 days (R-30D) are common after kidney transplant. R-30D are costly and associated with an increased risk of graft failure…2015 American Transplant Congress
Does Infection Impact On Tacrolimus Blood Levels in Kidney Transplant Recipients?
Background Tacrolimus (Tac) is the cornerstone of immunosuppressive therapy in kidney transplant recipients. It is metabolized by members of the cytochrome p450 (CYP) 3A subfamily…2015 American Transplant Congress
Efficacy and Safety of Desensitization Protocol Based On Rituximab Plus MMF in ABO-Incompatible Kidney Transplantation Without Splenectomy
Purpose: An open-label, single arm, multicenter clinical study has been conducted in Japan for prospective examination of the efficacy and safety of desensitization protocol with…
American Transplant Congress abstracts