ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    First Dose Tacrolimus Level Is Better Than CYP3A5 Genotyping in Prediction of Target Tacrolimus Dose

    N. Townamchai,1 W. Chancharoenthana,1 S. Wattanatorn,1 S. Vadcharavivad,2 P. Chariyavilaskul,3 A. Leelahavanichkul,4 Y. Avihingsanon,1 K. Praditpornsilpa.1

    1Department of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand; 2Department of Pharmacy Practice, Chulalongkorn University, Bangkok, Thailand; 3Pharmacokinetic Research Unit, Chulalongkorn University, Bangkok, Thailand; 4Department of Microbiology, Chulalongkorn University, Bangkok, Thailand.

    Background: Tacrolimus dose highly varies among Asian kidney transplant recipients. This can be explained by variety of CYP3A5 expression. CYP3A5 genotyping is highly recommended for…
  • 2015 American Transplant Congress

    Liver Fabrication Using Whole Organ Scaffold for Transplantable Graft in Large Animal

    K. Inomata,1 H. Yagi,1 K. Tazima,1 K. Sugiyama,1 M. Hieda,1 T. Hibi,1 Y. Abe,1 M. Kitago,1 M. Shinoda,1 O. Itano,1 T. Akaike,2 Y. Kitagawa.1

    1Surgery, Keio University, Tokyo, Japan; 2Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Tokyo, Japan.

    Background and aims: Orthotopic liver transplantation is only effective treatment for end-stage liver disease, however it is limited by shortage of donor livers. Therefore, novel…
  • 2015 American Transplant Congress

    The Association of Basiliximab and Antithymocyte Globulin Induction With Delayed Graft Function

    D. Felix,1 B. Astor,2 D. Hager,1 A. Djamali.2

    1Department of Pharmacy, University of Wisconsin Hospital and Clinics, Madison, WI; 2Department of Medicine - Division of Nephrology, University of Wisconsin Hospital and Clinics, Madison, WI.

    The impact of selection of induction immunosuppression agent on incidence of delayed graft function (DGF) remains unclear. A total of 1,980 deceased donor kidney transplant…
  • 2015 American Transplant Congress

    Blocking CD40/CD154 Co-Stimulation Prevents Acute Antibody-Mediated Renal Allograft Rejection Induced by Memory CD4 T Cells

    V. Gorbacheva, R. Fan, A. Valujskikh.

    Immunology, The Cleveland Clinic, Cleveland, OH.

    Immunosuppression-resistant alloreactive memory CD4 T cells induce robust responses against organ transplants. In murine heart allograft recipients donor-reactive memory CD4 T cells provide help for…
  • 2015 American Transplant Congress

    Controlling for Socioeconomic Barriers Reduces Racial Disparities in Transplant Pursuit

    A. Waterman,1 J. Peipert,1 C. Kynard-Amerson,1 A.-M. McSorley,1 A. Paiva,2 M. Robbins,2 L. Peace.3

    1David Geffen School of Medicine, UCLA, Los Angeles, CA; 2University of Rhode Island, Kingston, RI; 3Missouri Kidney Program, Columbia, MO.

    Compared to White dialysis patients, Black patients experience more socioeconomic barriers (SEBs) including higher financial insecurity and worse health insurance. To examine how SEBs affect…
  • 2015 American Transplant Congress

    Moderate KDPI (35-85) and High KDPI (>85) Grafts Yield Similar Graft Function and Survival

    A. Gupta,2 G. Francos,2 C. Gorn,3 A. Shah.1

    1Surgery, Thomas Jefferson University, Philadelphia, PA; 2Nephrology, Thomas Jefferson University, Philadelphia, PA; 3Transplantation, Thomas Jefferson University, Philadelphia, PA.

    Purpose – To study the impact of donor KDPI on post-transplant kidney function and survival.Methods – We reviewed the records of 309 deceased donor kidney…
  • 2015 American Transplant Congress

    Risks for Readmission Post-Renal Transplant: A Co-Morbid Condition

    M. John, A. Smith, I. Dortonne, A. Paramesh, M. Killackey, B. Lee, R. Zhang, J. Buell.

    Transplant Institute, Tulane University, New Orleans, LA.

    Background: Recently CMS addressed “excessive” readmission rates with a punitive 5% cut in reimbursement. For decades renal transplantation has been highly regulated with published outcomes…
  • 2015 American Transplant Congress

    Kidney Transplant Outcomes in Marijuana Users

    P. Shrivastava,1 A. Naik,1 A. Sakhuja,1 Y. Lu,1 Y. Huang,1 F. Barrantes,2 F. Luan,3 S. Kulshrestha,4 M. Samaniego.1

    1Dept of Internal Medicine, University of Michigan, Ann Arbor, MI; 2Presbyterian Kidney Transplantation, Albuquerque, NM; 3Dept of Kidney and Pancreas Transplantation, St. Barnabas Medical Center, Livingston, NJ; 4Dept of Internal Medicine, University of Iowa, Iowa City, IA.

    Introduction: As Marijuana use is gaining social acceptance, many transplant centers face questions regarding candidacy of users for kidney transplantation. Currently its impact on post-transplantation…
  • 2015 American Transplant Congress

    Desensitization Protocol Including Concomitant Bortezomib and Rituximab Did Not Reduce Calculated PRA Nor Mean MFI Values Among Waitlisted Patients for Deceased Donor Kidney Transplantation

    S. Kang,1 H. Lim,1 J. Jeong,1 E. Song,2 I. Yun,3 C. Ahn,1 J. Yang.1

    1Transplantation Center, Seoul National University Hospital, Seoul, Korea; 2Department of Laboratory Medicine, Seoul National University Hospital, Seoul, Korea; 3Department of Surgery, Konkuk University, Seoul, Korea.

    Highly sensitized (HS) patients (pts) seldom have chance to receive deceased donor kidney transplant (DDKT). A desensitization (DES) program including bortezomib was employed to facilitate…
  • 2015 American Transplant Congress

    National Outcomes of Donation After Cardiac Death (DCD) Liver Transplantation Are Equivalent to Donation After Brain Death (DBD) Liver Transplantation Using Older (DBD) Donor Livers

    R. Redfield, M. Rizzari, J. Scalea, L. Fernandez, A. D'Alessandro, J. Mezrich, D. Foley.

    University of Wisconsin, Madison, WI.

    Background: Multiple studies have demonstrated that outcomes of DCD liver transplantation (LTx) are inferior to DBD LTx. Thus DCD liver transplantation represents only 7% of…
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