Am J Transplant, Volume 5, Suppl 3 Archives - Page 166 of 170 - ATC Abstracts

2015 American Transplant Congress
The Synergistic Effect of Class II HLA Epitope-Mismatch and Non-Adherence on Acute Rejection and Graft Survival
C. Wiebe,^1,2 T. Nevins,³ W. Robiner,^3,4 W. Thomas,⁵ A. Matas,⁶ P. Nickerson.^1,2,8
¹Medicine, University of Manitoba, Winnipeg, MB, Canada; ²Transplant Immunology, Diagnostic Services of Manitoba, Winnipeg, MB, Canada; ³Pediatrics, University of Minnesota, Minneapolis, MN; ⁴Medicine, University of Minnesota, Minneapolis, MN; ⁵Public Health, University of Minnesota, Minneapolis, MN; ⁶Surgery, University of Minnesota, Minneapolis, MN; ⁷Immunology, University of Manitoba, Winnipeg, MB, Canada.
Predicting long-term outcomes in renal transplant recipients is essential to optimize medical therapy and determine the frequency of post-transplant pathologic and serologic monitoring. Non-adherence and…
2015 American Transplant Congress
Analysis of Causes of Graft Loss Among Kidney Transplant Patients Receiving Tacrolimus Vs Cyclosporine
M. Kamel,¹ M. Posadas Salas,¹ D. Taber,² M. Kadian,¹ M. Salazar,¹ P. Mohan,¹ T. Srinivas.¹
¹Department of Medicine, Medical University of South Carolina, Charleston, SC; ²Department of Surgery, Medical University of South Carolina, Charleston, SC.
Tacrolimus (FK) has surpassed cyclosporine (CYA) as the calcineurin inhibitor (CNI) of choice for the vast majority of kidney transplant (KTX) programs. Yet, CYA continues…
2015 American Transplant Congress
A Joint Survival Longitudinal Approach to Better Assess the Etiological Role of Risk Factors of Kidney Transplant Graft Failure
M.-C. Fournier,^1,2 E. Dantan,¹ Y. Foucher,^1,2 M. Giral.²
¹EA 4275 - SPHERE - Biostatistique, Pharmacoépidémiologie et Mesures Subjectives en Santé, Université de Nantes, Nantes, France; ²INSERM CR1064 Centre pour la Recherche en Transplantation et Immunointervention (CRTI), Institut Transplantation-Urologie-Néphrologie (ITUN), Nantes, France.
Background. Although risk factors of graft failure after renal transplantation have been widely considered, it is difficult to distinguish their etiological role: a direct association…
2015 American Transplant Congress
Split and Living Donor Versus Whole Liver Transplantation for Hepatocellular Carcinoma in Adult Recipients: A Single Center Analysis
O. Boillot, O. Guillaud, J. Dumortier.
Liver Transplant Unit, Edouard Herriot Hospital, lyon, France.
INTRODUCTIONThe use of partial liver grafts in the context of hepatocellular carcinoma (HCC) remains a matter ofdebate because of a supposed higher risk of cancer…
2015 American Transplant Congress
Prehypertension and Abnormal Fasting Glucose Are the Main Factors Associated With Progressive Deterioration of Renal Function in Kidney Donors
J. Arreola-Guerra,¹ M. Arvizu-Hernandez,² R. Correa-Rotter,² L. Morales-Buenrostro,² J. Alberu.¹
¹Transplantation, National Institute of Nutrition and Medical Sciences Salvador Zubirán, Mexico City, Mexico; ²Nephrology and Mineral Metabolism, National Institute of Nutrition and Medical Sciences Salvador Zubirán, Mexico City, Mexico.
Background: For reasons unclarified, some kidney donors (KD) are patients (pts) that throughout its evolution remain with the same renal function (RF) or even continue…
2015 American Transplant Congress
Living Kidney Donation in the Elderly: The United Kingdom Experience
Z. Ahmed,¹ R. Tamburrini,¹ L. Pankhurst,² N. Kessaris,¹ N. Mamode.¹
¹Renal and Pancreatic Transplantation, Guy's Hospital, London, United Kingdom; ²Department of Clinicsl Trials and Statistics, NHS Blood and Transplant, Bristol, United Kingdom.
Introduction: The increasing demand for organs has led many institutions to accept elderly patients onto their living donor programmes. However no large UK based datasets…
2015 American Transplant Congress
Induction Avoidance in 2-Haplotype-Matched White Living Kidney Transplantation
Z. Brifkani,¹ T. Alhamad,¹ T. Horwedel,² R. Delos Santos,¹ T. Maw,¹ D. Brennan.¹
¹Transplant Nephrology, Washington University in St. Louis, St. Louis, MO; ²Barnes Jewish Hospital, St. Louis, MO.
Background: We hypothesize that 2-haplotype matched white living kidney transplant recipients carry a low immunologic risk for rejection, and therefore do not give induction therapy…
2015 American Transplant Congress
The Preservation Technique Modulates the Immunological Milieu in Lung Transplantation and Affects the Pro-/ Anti-Inflammatory Balance
M. Seyda,¹ B. Wiegmann,³ B. Mueller,² C. Neudoerfl,¹ A. Akhdar,¹ K. Daemen,¹ A. Haverich,^3,4 G. Warnecke,^3,4 C. Falk.^3,5
¹Inst. of Transplant Immunology, IFB-Tx, Hanover Medical School, Hanover, Germany; ²MorphoSys, Munich, Germany; ³Cardiothoracic, Transplantation and Vascular Surgery, Hanover Medical School, Hanover, Germany; ⁴German Center for Lung Research, Gießen, Germany; ⁵German Center for Infection Research, Braunschweig, Germany.
Little is known regarding the influence of different preservation techniques (i.e. cold static storage with Perfadex® or Celsior® solution) on the immunological milieu, especially lung-resident…
2015 American Transplant Congress
Change in Frailty Status Over Time Among In-Center Hemodialysis ESRD Patients in the ACTIVE/ ADIPOSE Study
B. Tao, J. Gander, N. Kutner, S. Pastan, R. Zhang, R. Patzer.
Emory University, Atlanta, GA.
Introduction: Frailty among End Stage Renal Disease (ESRD) is associated with poor health outcomes, including delayed graft function and hospitalization following transplantation. Although frailty is…
2015 American Transplant Congress
Highly Accurate High-Resolution HLA Imputation Using Dense Genotyping Data
B. Keating,¹ Y. Li,¹ T. Guettouche,² K. Olthoff,¹ A. Shaked.¹
¹Surgery (Division of Transplantation), University of Pennsylvania, Philadelphia, PA; ²Genetics, Children's Hospital of Philadelphia, Philadelphia, PA.
HLA similarity between donors (D) and recipients (R) of solid organ transplantation (SOT) plays a central role in determining the risk of rejection or graft-versus-host…