ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    The Effect of Preformed and De Novo Donor-Specific Antibodies (DSA) in Acute Rejection (AR) After Liver Transplantation (LTX)

    M. Koch,1 M. Runnebaum,1 M. Goebel,2 H. Thude,1 M. Sterneck,1 M. Marget,2 B. Nashan.1

    1Hepatobiliary Surgery and Transplantation, University Medical Centre, Hamburg, Germany; 2HLA-Laboratory, University Medical Centre, Hamburg, Germany.

    BACKGROUND: The role of preformed and den novo formed DSA in LTX is not fully revealed. The aim of our study was to determine if…
  • 2015 American Transplant Congress

    Graft-Versus-Host Disease After Orthotopic Liver Transplantation: Multivariate Analysis of Risk Factors

    M. Elfeki, P. Genco, S. Pungpapong, J. Nguyen, D. Harnois.

    Transplantation, Mayo Clinic, Jacksonville, FL; Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, FL.

    Introduction:Acute graft versus host disease (GVHD) is a rare fatal complication following orthotopic liver transplantation (OLT). It involves activation of donor T lymphocytes by antigen…
  • 2015 American Transplant Congress

    Effect of 2007 CMS Conditions of Participation on High Risk Renal Transplantation: A Study of the United States Renal Data System

    D. John, A. Brar, F. Tedla, N. Sumrani, E. Timpo, M. Salifu.

    Division of Transplantation, SUNY Downstate Medical Center, Brooklyn, NY.

    BACKGROUND: On June 28, 2007, CMS introduced new Conditions of Participation (CoP) for Transplant Centers- the impact of these regulations on adult patients at high…
  • 2015 American Transplant Congress

    Aging Enhances Immunosuppressives Capacities of Tacrolimus By Functional Changes of CD4+ T-Cells

    F. Krenzien,1 M. Quante,1 A. ElKhal,1 H. Uehara,1 R. Abdi,2 B. Slegtenhorst,1 H. Biefer,1 S. Tullius.1

    1Transplant Surgery Research Laboratory and Division of Transplant Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; 2Transplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

    Immunosenescence has broad consequences on alloimmunity and immunosuppression in the elderly may require age-adaptation. Here, we investigated the influence of aging on the effectivity of…
  • 2015 American Transplant Congress

    Impact of HMOX1 Genetic Variation in Pancreas Transplant Recipients On Long-Term Graft Outcome

    C. Duff,1 A. Hamilton,1 S. Mittal,2,3,4 M. Barnardo,2,3 S. Fuggle,2,3 P. Friend,2,3 S. Gough,1,4 M. Simmonds.1

    1Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), University of Oxford, Oxford, United Kingdom; 2Oxford Transplant Centre, Oxford University Hospitals NHS Trust, Oxford, United Kingdom; 3Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom; 4Oxford National Institute for Health Research Biomedical Research Centre, Oxford, United Kingdom.

    Variation within the heme oxygenase 1 (HMOX1) gene, essential for heme catabolism and a known inflammatory and immune regulator, is proposed to play a role…
  • 2015 American Transplant Congress

    Treatment of Hypertrophic Osteoarthropathy in an Intestinal Transplant Patient After Acute Cellular Rejection

    M. Keck.

    Department of Pharmaceutical and Nutrition Care, Nebraska Medicine, Omaha, NE.

    Background:Hypertrophic osteoarthropathy involves abnormal proliferation of bone at distal extremities. It involves clubbing, periostitis of tubular bones and synovial effusions. Some causes of secondary hypertrophic…
  • 2015 American Transplant Congress

    Predictive Value of Regadenoson Scans After Heart Transplant

    J. Kawano, M. Kittleson, J. Patel, B. Azarbal, F. Liou, S. Siddiqui, D. Wong, D. Chang, D. Ramzy, L. Czer, J. Kobashigawa.

    Cedars-Sinai Heart Institute, Los Angeles, CA.

    Purpose: Cardiac allograft vasculopathy (CAV) is one of the major factors limiting long-term survival after heart transplantation. The use of annual coronary angiograms is an…
  • 2015 American Transplant Congress

    Reduced Urinary Uromodulin (UMOD)-Levels Are associated With Urinary Tract Infections (UTI) After Renal Transplantion

    K. Stahl, J. Beneke, H. Haller, W. Gwinner, M. Schiffer.

    Nephrology, Hannover Medical School, Hannover, Germany.

    Background:Urinary tract infection (UTI) following renal transplantation remains the most common post transplant bacterial infection and appears to be closely linked to reduced allograft and…
  • 2015 American Transplant Congress

    Persistent Expansion of DX5- Memory NK Cells in the Liver After Intraportal Islet Transplantation

    Y. Saeki, K. Ishiyama, N. Ishida, Y. Tanaka, H. Ohdan.

    Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.

    Introduction: We have previously demonstrated that liver NK cells play a pivotal role in islet graft loss during the early phase after intraportal islet transplantation…
  • 2015 American Transplant Congress

    Lifor Organ Preservation Solution Protects Pulmonary Microvasculature in a Rat Model of Ex Vivo Lung Perfusion and Transplantation

    T. Okamoto,1,3 A. Yasuda,1,2 D. Mathisen,1,3 H. Ott.1,3

    1Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA; 2Department of Anesthesiology, Massachuetts General Hospital, Boston, MA; 3Department of Surgery, Massachuetts General Hospital, Boston, MA.

    A. Ex Vivo Lung Perfusion (EVLP) has emerged as an innovative method for lung preservation. Microvascular dysfunction and breakdown of endothelial barrier during EVLP are…
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