ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Acute Kidney Injury in the Early Post Kidney Transplant Period: Frequency, Etiology and Significance

    B. Kiberd,1 S. Cimen,1 K. Tennankore.2

    1Surgery, Dalhousie University, Halifax, NS, Canada; 2Medicine, Dalhousie University, Halifax, NS, Canada.

    Acute kidney injury (AKI) post kidney transplant has not been well described using current diagnostic criteria. The frequency and etiology of AKI in the first…
  • 2015 American Transplant Congress

    Recurrent IgA Nephropathy in Kidney Transplant Recipients Receiving a Steroid Sparing Immunosuppression Protocol

    K. Koutroutsos,1 R. Charif,1 D. Goodall,1 C. Roufosse,2 J. Galliford,1 T. Cook,2 D. Taube,1 M. Loucaidou.1

    1Kidney and Transplant Centre, Imperial Healthcare NHS Trust, London, United Kingdom; 2Department of Histopathology, Imperial Healthcare NHS Trust, London, United Kingdom.

    Background: Steroid sparing immunosuppression is increasingly used in order to avoid the many well-known side effects of steroids. It has been argued that steroid use…
  • 2015 American Transplant Congress

    Nomogram for Predicting Patient Survival After Withdrawal of Life-Sustaining Treatment in Patients With Devastating Neurological Injury

    G. Xu, X. He.

    Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, guangzhou, China; Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, guangzhou, China.

    Objective:Reliable prediction of time of death after withdrawal of life-sustaining treatment in patients with devastating neurological injury is crucial to successful donation after circulatory death.…
  • 2015 American Transplant Congress

    “Unexpected” Positive Crossmatchs in Zero-HLA-A-B-DR Mismatched or HLA-DR-Matched Organs

    K. Haarberg,1 M. Cusick,1 M. Abecassis,1 A. Jaramillo,2 B. Kaplan,3 A. Tambur.1

    1Transplant Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL; 2Gift of Hope Organ and Tissue Donor Network, Itasca, IL; 3Center for Transplantation, University of Kansas Medical Center, Kansas City, KS.

    Deceased donor kidney allocation is currently prioritized by HLA-A,-B and-DR serologic matching, which disregards both specificity at the allele level, and the contributions of HLA-C,-DQ,…
  • 2015 American Transplant Congress

    Improving ABMR Diagnostics Through Advanced Anti-HLA Antibody Screening Techniques

    R. Ponsirenas,1,2 H. Cazarote,1,2 S. Shimakura,3 J. Valdameri,1 F. Contieri,4 C. von Glehn,1,2 M. Susin.1,2

    1Transplant Immunology Laboratory, Pontifícia Universidade Católica do Paraná, Curitiba, Parana, Brazil; 2Medicine School, Pontifícia Universidade Católica do Paraná, Curitiba, Parana, Brazil; 3Departament of Statistics, Universidade Federal do Parana, Curitiba, Parana, Brazil; 4Kidney Transplant Unit, Hospital Evangélico de Curitiba, Curitiba, Parana, Brazil.

    The identification of low-level antibodies by single antigen bead methodology has brought advancements in risk evaluation of kidney transplants recipients. However, the use of the…
  • 2015 American Transplant Congress

    Kidney Transplantation (KTx) With Positive Crossmatch (XM) but No Donor Specific Antibody (DSA)

    J. Verbesey, O. Timofeeva, L. Dong, B. Javaid, G. Monica, A. Gilbert, J. Moore, P. Weems, S. Ghasemian, S. Rosen-Bronson, M. Cooper.

    MedStar Georgetown Transplant Institute, Washington, DC.

    Purpose: Prior to KTx, a XM is performed between the intended recipient and donor. This XM can be positive despite no DSA. It can be…
  • 2015 American Transplant Congress

    Novel Flow Cytometry Method for Detecting Complement-Fixing Blood Group IgG Antibody in ABO-Incompatible Renal Transplantation

    T. Ishizuka,1 M. Yasuo,1 Y. Ishida,1 H. Miura,1 K. Iwadoh,2 T. Murakami,2 K. Kitajima,2 I. Nakajima,2 S. Fuchinoue.2

    1Transplant Immunology, Tokyo Women's Medical University, Shinjuku ward, Tokyo, Japan; 2Surgery III, Tokyo Women's Medical University, Shinjuku ward, Tokyo, Japan.

    【Background】We experienced a hyperacute rejection (HAR) in ABO-incompatible renal transplantation (ABO-I RTx) on POD 0. We hypothesized that complement-fixing IgG anti-A/B blood group antibody (anti-A/B…
  • 2015 American Transplant Congress

    Immune-Mediated Injury in Kidney Transplant Recipients Treated With Alemtuzumab Induction and a Steroid Avoidance Protocol

    R. Sapir-Pichhadze, T. Mahbub, C. Saw, D. Baran.

    McGill University Health Centre, Montreal, Canada.

    Study purpose: We evaluated short-term clinical and immunological outcomes of kidney transplant recipients who received alemtuzumab induction and a steroid-avoidance protocol.Methods: This is a retrospective…
  • 2015 American Transplant Congress

    Clinical Consequences of Immune-Mediated Allograft Arteriosclerosis: A Population Based Study

    A. Loupy, Vernerey, Viglietti, Aubert, Duong van Huyen, Bruneval, Empana, Suberbielle, Glotz, Jouven, Legendre, Lefaucheur.

    Paris Translational Research Center for organ Transplantation, Paris, France.

    BACKGROUNDThe role of circulating antibodies and alloimmune response beyond traditional cardiovascular risk factors in the development of accelerated arteriosclerosis and its long-term clinical consequences is…
  • 2015 American Transplant Congress

    Serial Changes in Body Composition After Kidney Transplantation

    S. Deger,1 A. Bian,2 G. Chen,2 T. Ikizler,1 K. Birdwell.1

    1Medicine, Vanderbilt University Medical Center, Nashville, TN; 2Biostatistics, Vanderbilt University Medical Center, Nashville, TN.

    BACKGROUND: A significant long-term nutritional problem after kidney transplantation is obesity. We examined the changes in body composition after transplantation and its determinants.METHODS: A total…
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