Am J Transplant, Volume 5, Suppl 3 Archives - Page 156 of 170 - ATC Abstracts

2015 American Transplant Congress
Ten-Year Follow-Up After Live Kidney Donation – A Prospective Cohort Study
S. Janki,¹ K. Klop,¹ I. Dooper,² W. Weimar,³ J. IJzermans,¹ N. Kok.¹
¹Department of Surgery, Division of HPB and Transplant Surgery, Erasmus MC, University Medical Center, Rotterdam, Netherlands; ²Department of Nephrology, Radboud University Medical Center, Nijmegen, Netherlands; ³Department of Nephrology, Erasmus MC, University Medical Center, Rotterdam, Netherlands.
BACKGROUNDPreviously reported short-term results after live kidney donation, show no negative consequences for the donor. The occurrence of e.g. cardiovascular diseases takes years to emerge,…
2015 American Transplant Congress
Pre-Existing Coronary Artery Disease in Lung Transplantat Recipients: Does It Impact Outcomes?
S. Khandhar,¹ L. Tefera,² E. Volz,² F. Selzer,³ R. Kormos,² C. Bermudez.²
¹Heart and Vascular Institute at Penn-Presbyterian Medical Center, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA; ²Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA; ³Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Womens Hospital, Boston, MA.
INTRODUCTION:In patients undergoing lung transplantation (LTx), the impact of pre-existing coronary artery disease (CAD) on long-term outcomes is not well understood. This study examines the…
2015 American Transplant Congress
Elderly Transplant Recipients Have Improved Graft Survival
S. Reule,¹ R. Foley,¹ A. Matas,² H. Ibrahim.¹
¹Department of Medicine, University of Minnesota, Minneapolis, MN; ²Department of Surgery, University of Minnesota, Minneapolis, MN.
Background: The upper age limit to receive a kidney transplant has progressively risen, but the outcomes of elderly (ages > 70) transplant recipients remain understudied.…
2015 American Transplant Congress
BK Virus-Specific Polyfunctional CD8+ T Cells Predicts Successful Control of BK Viremia After Kidney Transplantation
J. Schaenman,¹ Y. Korin,² T. Sidwell,² F. Kandarian,² N. Harre,² P.-T. Pham,³ S. Bunnapradist,³ G. Danovitch,³ J. Veale,⁴ H. Gritsch,⁴ E. Reed.²
¹Medicine/Infectious Diseases, David Geffen School of Medicine (DGSOM) at UCLA, Los Angeles, CA; ²UCLA Immunogenetics Center, DGSOM at UCLA, Los Angeles, CA; ³Medicine/Nephrology, DGSOM at UCLA, Los Angeles, CA; ⁴Urology, DGSOM at UCLA, Los Angeles, CA.
Introduction: BK Virus associated nephropathy (BKN) remains an important cause of graft loss after kidney transplantation. We hypothesized that analysis of the anti-BK virus immune…
2015 American Transplant Congress
The Association Between Donor & Recipient Gene Variants and Tacrolimus Safety & Efficacy in a Diverse Cohort of Kidney Transplant Recipients
D. Taber, T. Srinivas, N. Pilch, M. Gebregziabher, L. Egede, P. Baliga, K. Chavin.
Medical University of South Carolina, Charleston, SC.
Previous studies have associated donor P-glycoprotein (PGP) gene variants (ABCB1) with risk of developing CNI-toxicity, while also establishing recipient CYP3A5*1 and ABCB1 gene variants are…
2015 American Transplant Congress
DNA Methylation Classifier Associates With Long-Term Graft Function Post-Kidney Transplantation
J. Suh,¹ D. Maluf, K. Archer,² T. Lee,¹ L. Gallon,³ V. Mas.¹
¹UVA, Charlottesville, VA; ²VCU, Richmond, VA; ³Noerthwestern University, Chicago, IL.
"Background. Late graft failure is a major problem after kidney transplantation (KT) mainly due to chronic renal allograft dysfunction (CRAD). Data about common pathways of…
2015 American Transplant Congress
Inhibition of mTOR Modulates SLPI Expression: A Potential Role in Kidney Transplant Patients
N. Ambrosi,¹ A. Dotta,² C. Pizarro,² D. Guerrieri,¹ A. Gonzalez,² C. Leiva,² L. Leon,² J. Mendiberri,³ M. Rial,² C. Incardona,⁴ E. Chuluyan,¹ D. Casadei.²
¹CEFYBO, UBA, Buenos Aires, Argentina; ²Fundacion 3er Milenio, INBA, Buenos Aires, Argentina; ³UNICEN, Olavarria, Argentina; ⁴Fundación GADOR, Buenos Aires, Argentina.
Secretory leukocyte protease inhibitor (SLPI) is a serine protease inhibitor secreted by inflammatory and epithelial cells. It functions as an endogenous immunomodulatory, with antiinflammatory and…
2015 American Transplant Congress
Clinical and Biochemical Results of BK Virus Nephropathy in Kidney Allograft Recipients
B. Canbakan,¹ I. Akdağ,¹ ö. Merhametsiz,¹ ö. Yayar,² E. Oğuz,¹ M. Kiliç,³ D. Ayli.¹
¹Nephrology, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey; ²Nephrology, Atatürk Training and Research Hospital, Ankara, Turkey; ³General Surgery, Atatürk Training and Research Hospital, Ankara, Turkey.
BK virus (BKV) nephropathy has emerged as a significant cause of graft dysfuction in kidney allograft recipients after using powerful immunosupressive treatment protocols in recent…
2015 American Transplant Congress
Distinct Subtypes of Rejection in a Novel Non Human Primate Model of Sensitization
C. Burghuber,^1,2 J. Kwun,^1,3 F. Leopardi,³ A. Gibby,¹ A. Farris,¹ N. Iwakoshi,¹ S. Knechtle.^1,3
¹Emory University, Atlanta, GA; ²Medical University Vienna, Vienna, Austria; ³Duke University, Durham, NC.
[Background] Preformed and newly formed alloantibody post transplantation (TX) can significantly deteriorate graft survival. Patterns of humoral rejection in sensitized patients varies significantly due to…
2015 American Transplant Congress
Racial/Ethnic Differences in the Association Between Hospitalization and Kidney Transplantation Among Waitlisted End Stage Renal Disease (ESRD) Patients: A Multi-Level Mixed Modeling Approach
K. Newman,¹ S. Fedewa,¹ M. Jacobson,¹ A. Adams,² R. Zhang,² R. Patzer.^1,2
¹Emory University Rollins School of Public Health, Atlanta; ²Emory University School of Medicine, Atlanta.
Background: Racial disparities in access to kidney transplantation exist among End Stage Renal Disease (ESRD) patients, even after placement on the deceased donor waitlist. One…