2015 American Transplant Congress
Non-Chimeric HLA-Identical Renal Transplant Tolerance: Regulatory Immunophenotypic/Genomic Biomarkers
Background. We previously described 3-year results of a non-chimeric tolerance protocol in HLA-identical living donor renal transplant (RT) recipients and now report on longer term,…2015 American Transplant Congress
Controlling Alloreactive B Cell Responses in Sensitized Recipients With CTLA-4Ig
Sensitized recipients are defined by the presence of pre-transplant donor-specific antibodies and have significantly poorer graft outcomes compared to unsensitized recipients despite efforts to desensitize.…2015 American Transplant Congress
Effect of Patient Functional Status on the Associations Between Kidney Transplant Waitlisting, Race, and U.S. Region
Background: Black race and Southeastern residence at the start of end-stage renal disease (ESRD) are associated with reduced access to the U.S. kidney transplant waitlist,…2015 American Transplant Congress
Thymoglobulin Versus IL2RA: Three Year Results of a Randomized Controlled Trial
Transplant, MUSC, Charleston, SC.
This is a three year follow-up of a prospective, randomized controlled trial (RCT) to determine the safety and efficacy of induction with rabbit antithymocyte globulin…2015 American Transplant Congress
Impact of Abdominal Aortic Calcification in Living Kidney Donors
Introduction: To assess the association between abdominal aortic calcification (AAC) and renal function of living kidney donor and to evaluate the value of an AAC…2015 American Transplant Congress
Predictors of Time to Recurrence and Mortality Associated With Recurrent Hepatocellular Carcinoma After Liver Transplantation
Transplantation, UCLA, Los Angeles, CA.
Background: While recurrent hepatocellular carcinoma (HCC) after liver transplantation (LT) portends a poor prognosis, adjuvant therapy may prolong survival. We sought to identify factors that…2015 American Transplant Congress
Blocking CD4 T Cell Helper Functions Improves Efficacy of ATG Treatment in Sensitized Transplant Recipients
Immunology, Cleveland Clinic, Cleveland, OH.
Antibody mediated lymphocyte depletion is used in clinical transplantation to improve graft function. While the presence of donor-reactive memory T cells is the primary rationale…2015 American Transplant Congress
Rat Forelimb Allotransplantation: A Novel Microsurgical Model for Optimized Functional Assessment After Reconstructive Transplantation
Background:Functional outcomes following vascularized composite allotransplantation (VCA) have been promising, but there is still room for improvement. Studies to investigate strategies to overcome this obstacle…2015 American Transplant Congress
Effective Control of Anti-Xenogeneic IL-17 Response for Tolerance Induction in Xenogeneic Islet Cell Transplantation
We have previously shown that peri-transplant infusion of donor cells treated with 1-ethyl-3-(3'-dimethylaminopropyl)-carbodiimide (ECDI) in combination with peri-transplant anti-CD20 and rapamycin induce permanent porcine islet…2015 American Transplant Congress
Cardiac Troponin T (cTNT) in the Assessment of Kidney Transplant (KTx) Benefit and Risk
1Nephrology, Mayo Clinic, Rochester, MN; 2Surgery, Mayo Clinic, Rochester, MN.
Introduction. Compared to waiting list (WL) KTx improves patient survival. However, mortality may increase early post-KTx. cTNT level at candidate evaluation is a strong, independent…
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