ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Histologic Findings in Pre-transplant AT1Rab + ve Patients Point to an Increase in Sub-Intimal Fibrosis During Acute Rejection and in 12 mo. Protocol Renal Graft Biopsies

    A. González-Almada, J. Arreola-Guerra, E. Cuevas, M. Vilatoba, A. Contreras, A. Sanchez-Cedillo, J. Alberu, N. Uribe-Uribe.

    1Transplantation, 1aNephrology-Mineral Metabolism, 1bPathology, Inst Nal de Ciencias Medicas y Nutricion SZ, Mexico City, Distrito Federal, Mexico.

    Previous reports have described an increase in arteritis during acute rejection (AR) in angiotensin II type 1 receptor antibody (AT1Rab) positive (ve+) kidney transplant recipients…
  • 2015 American Transplant Congress

    Post-Transplant Recurrence of Calcium Oxalate Crystals in Primary Hyperoxaluria Type 1 Detected by Surveillance Biopsies: Incidence, Risk Factors, and Effect on Graft Function

    L. Cornell, N. Pamidi, R. Mehta, M. Stegall, E. Lorenz, J. Heimbach, D. Milliner.

    Mayo Clinic, Rochester, MN.

    Background: Primary hyperoxaluria type 1 (PH1) is a rare metabolic defect that results in oxalate over-production by the liver and leads to renal disease due…
  • 2015 American Transplant Congress

    Pediatric Living Donor Liver Transplantation at KFSH&RC – Implementation of the Laparoscopic Retrieval in a High Volume Center

    M. Boehnert, M. Shagrani, T. Al Goufi, D. Broering.

    Organ Transplant Centre, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.

    Since the first successful pediatric liver transplantation was performed in 1967 the survival rate increased from 30 % to currently above 90 %. This is…
  • 2015 American Transplant Congress

    Isolated Microcirculation Inflammation Negatively Impacts Renal Graft Function at 5 Years

    A. Chapelet,1 M. Touzot,1 M. Fournier,2 A. Cesbron,3 K. Renaudin,4 A. Moreau,4 E. Morelon,5 D. Anglicheau,6 M. Giral.1

    1Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France; 2EA 4275 SPHERE—Biostatistics, Pharmacoepidemiology and Subjective Measures in Health Sciences, University of Nantes, Nantes, France; 3Etablissement Français du Sang (EFS), Nantes, France; 4Service d'Anatomie et Cytologie Pathologiques, CHU Nantes, Nantes, France; 5Service de Néphrologie, Transplantation et Immunologie Clinique, Hôpital Edouard Herriot, Lyon, France; 6Service de Transplantation Rénale et de Soins Intensifs, Hôpital Necker, Paris, France.

    BACKGROUND: Microcirculation inflammation (MI, ie: glomerulitis (g) and peritubular capillaritis (ptc)) associated with anti-HLA Donor Specific Antibody (DSA) with or without C4d deposits in ptc…
  • 2015 American Transplant Congress

    Correlation Between C3d-Binding De Novo Donor Specific HLA Antibodies and Rejection in Kidney Transplant Recipients

    M. Cusick, K. Haarberg, J. Friedewald, A. Tambur.

    Comprehensive Transplant Center, Northwestern University, Chicago, IL.

    Donor specific antibodies (DSA) directed against HLA arising de novo post-kidney transplant are a major cause of graft loss, termed antibody mediated rejection (AMR). Currently,…
  • 2015 American Transplant Congress

    Preformed Anti-HLA DP Donor Specific Antibodies Are Clinically Significant in Renal Transplantation

    V. Dibbur, M. Willicombe, P. Brookes, R. Sergeant, A. Wardle, D. Taube.

    Renal and Transplant Medicine, Imperial Healthcare NHS Trust, London, United Kingdom.

    Background: Whilst preformed [PF] anti-HLA A, B, DR and DQ donor specific antibodies [DSAbs] are associated with poorer allograft outcomes secondary to antibody mediated injury,…
  • 2015 American Transplant Congress

    Octogenarian Kidney Transplant Recipients: A Single Center Experience

    B. Ravichandran, T. Sparkes, B. Thomas, F. Rasetto, M. Gillespie, M. Moss, S. Bartlett, B. Masters.

    University of Maryland Medical Center, Baltimore, MD.

    Background: Elderly patients are the fastest growing population requiring kidney transplantation internationally. Previous studies have shown a survival benefit for kidney transplantation when compared to…
  • 2015 American Transplant Congress

    Induction With an Interleukin-2 Receptor Antagonist in Sensitized Adult Kidney Transplant Recipients Is Highly Effective and Safe

    J. Casale, J. Fleming, D. Taber, C. Staino, K. Boyle, K. Covert, N. Pilch, H. Meadows, C. Mardis, K. Chavin, C. Bratton, J. McGillicuddy, P. Baliga.

    MUSC, Charleston, SC.

    Background: The effectiveness and safety of induction with basiliximab (IL2RA) in sensitized kidney transplant recipients is not clearly established. The aim of this study was…
  • 2015 American Transplant Congress

    Negative Exercise Myocardial Perfusion Scintigraphy Discards Silent Coronary Artery Disease in High Cardiovascular Risk Patients Awaiting for Kidney Transplantation

    E. Melilli,1 V. Navarro,2 O. Bestard,1 A. Gomez,3 J. Cruzado.1

    1Kidney Transplantation Unit, Hospital de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain; 2Nephrology Service, Hospital San Juan de Dios, San Jose, Costa Rica; 3Cardiac Intensive Care Unit, Hospital de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.

    Study Purpose:Screening for silent coronary artery disease (SCAD) in patients awaiting kidney transplantation is still controversial. Indeed, guidelines of some scientific societies show important discrepancies.…
  • 2015 American Transplant Congress

    Impact of Proton Pomp Inhibitors on Hypomagnesemia and Arterial Stiffness in Renal Transplant Recipients

    S. Sezer,1 B. Gurlek Demirci,1 M. Erkmen Uyar,1 S. Uyanik,2 M. Haberal.3

    1Department of Nephrology, Baskent University Faculty of Medicine, Ankara, Turkey; 2Department of Intrenal Medicine, Baskent University Faculty of Medicine, Ankara, Turkey; 3Department of General Surgery, Baskent University Faculty of Medicine, Ankara, Turkey.

    Purpose: Hypomagnesemia predicts cardiovascular morbidity and mortality in the general population and accelerated loss of kidney function in renal transplant recipients (RTRs). Proton pomp inhibitors…
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