ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Moderate Rejection Episode of Face Transplant After mTOR Conversion to Preserve Renal Function

    R. Barth,1 B. Bojovic,1 J. Woodall,1 M. Uluer,1 C. Drachenberg,1 C. Shaffer,1 N. Kelly,1 E. Rodriguez,2 S. Bartlett.1

    1University of Maryland School of Medicine, Baltimore; 2New York Medical University, New York City.

    Face and hand vascularized composite allografts (VCA) have demonstrated durable graft survivals with conventional immunosuppression but with the appearance of renal dysfunction. Management strategies that…
  • 2015 American Transplant Congress

    Glomerulosclerosis Patterns Are Non-Uniform Throughout the KDPI Spectrum With Impact on Biopsy Evaluation of Kidneys for Transplant

    M. Jendrisak,1 K. Mulawa,1 M. Harmon,1 D. Cimbaluk.2

    1Gift of Hope Organ & Tissue Donor Network, Itasca, IL; 2Rush University, Chicago, IL.

    Background: The kidney donor profile index (KDPI) stratifies kidney quality with direct bearing on organ allocation and utilization. Procurement biopsy is commonly performed and factored…
  • 2015 American Transplant Congress

    T-Cell Depletion Versus Interleukin-2 Antagonists in a Kidney Transplant Model of Sensitized Rhesus Macaques

    C. Burghuber,1,2 J. Kwun,1 E. Page,1 F. Leopardi,3 A. Gibby,1 A. Farris,1 N. Iwakoshi,1 S. Knechtle.1

    1Emory University, Atlanta, GA; 2Medical University Vienna, Vienna, Austria; 3Duke University, Durham, NC.

    [Background] Sensitized patients comprise up to a third of the kidney waiting list. Preformed and newly formed alloantibodies post transplantation (TX) deteriorate graft survival, recall…
  • 2015 American Transplant Congress

    Racial Disparities in Access to Kidney Re-Transplantation in the United States

    C. Garrett, R. Patzer, R. Zhang, A. Adams.

    Surgery, Emory Transplant Center, Atlanta, GA.

    Introduction: The number of patients with a failed kidney transplant who are being considered for re-transplantation has steadily increased over the past few years. It…
  • 2015 American Transplant Congress

    Utilization and Characteristics of Kidney Donors in the US by OPTN-Defined Increased Risk Donor Status

    M. Ison,1,2 B. Ho,2 J. Leventhal,2 D. Ladner.2

    1Infectious Diseases, Northwestern University, Chicago; 2Organ Transplantation, Northwestern University, Chicago.

    Background: The number of candidates in need of kidney transplantation is far larger than the number of organ donors. To expand the organ pool, there…
  • 2015 American Transplant Congress

    Early Hospital Readmission and Distance from Transplant Center

    E. King,1 L. Kucirka,1 M. McAdams-DeMarco,1,2 A. Massie,1,2 D. Segev.1,2

    1Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD; 2Epidemiology, Johns Hopkins University, School of Public Health, Baltimore, MD.

    Background: Early hospital readmission occurs in 31% of kidney transplant (KT) recipients and may be associated with mechanistic factors not previously captured in patient-level risk…
  • 2015 American Transplant Congress

    Incidence and Clinical Severity of Hypogammaglobulinemia (Hypo-IgG) in Highly-HLA Sensitized Patients (HS) Undergoing Desensitization (DES)

    A. Vo,1 S. Ge,2 A. Petrosyan,2 M. Toyoda,2 J. Choi,1 J. Kahwaji,1 A. Peng,1 R. Villicana,1 S. Jordan.1

    1Kidney Transplant, Cedars-Sinai Medical Center, LA; 2Transplant Immunology Laboratory, Cedars-Sinai Medical Center, LA, CA.

    Introduction: Desensitization therapies (DES) have dramatically improved rates of transplantation among HS patients. However, antibody-reduction and B-cell/plasma cell directed therapies could have implications for humoral…
  • 2015 American Transplant Congress

    Impact of Baseline and Postoperative Isoagglutinin Titer on Clinical Outcomes in ABO-Incompatible Living Donor Kidney Transplantation

    E. Shin,1 H. Cho,1 H. Kim,1 C. Baeck,1 H. Yu,1 D. Han,2 S.-K. Park.1

    1Internal Medicine, Asan Medical Center, Seoul, Republic of Korea; 2General Surgery, Asan Medical Center, Seoul, Republic of Korea.

    Background : ABO-incompatible (ABO-i) kidney transplantation (KT) has expanded in consequence of the development of desensitization protocol. However, the impact of baseline and postoperative isoagglutinin…
  • 2015 American Transplant Congress

    Induction Therapy With either Anti-Thymocyte Antibodies or Il2 Receptor Inhibitors Appears to Decrease the Risk of Graft Loss in DCD Liver Transplantation Compared to No Induction Therapy

    S. Rayhill, J. Haldorson, A. Dick, S. Nazarian, L. Sibulesky, M. Montenovo, L. Yu, I. Javid, T. Pearson, R. Bakthavatsalam, P. Healey, J. Perkins, J. Reyes.

    University of Washington, Seattle.

    An analysis of our center's outcomes in DCD liver transplants suggested that induction with anti-thymocyte antibody preparations (ATG) may reduce the risk of graft loss…
  • 2015 American Transplant Congress

    Impact of Donor Post-Extubation O2 Delivery on Recipient Hypoxic Cholangiopathy in Donation After Circulatory Death Liver Transplantation: The University of Colorado Experience

    T. Chirichella,1 C. Dunham,2 M. Zimmerman,4 K. Conzen,1 S. Kelley,3 E. Phelan,1 T. Steinberg,1 T. Nydam,1 T. Bak,1 I. Kam,1 M. Wachs.1

    1Transplant Surgery, University of Colorado Hospital, Aurora, CO; 2Department of Surgery, St. Elizabeth Health Center, Youngstown, OH; 3Donor Alliance Organ Procurement Organization, Denver, CO; 4Transplant Surgery, Medical College of Wisconsin, Milwaukee, WI.

    The critical shortage of deceased organ donors has led to increased utilization of DCD liver grafts. The purpose of this study was to evaluate DCD…
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