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American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Outcomes of Live Kidney Donors Who Develop End Stage Renal Disease

    A. Muzaale, A. Massie, L. Kucirka, D. Segev.

    Johns Hopkins, Baltimore.

    Kidney donors can develop ESRD after donation, but the outcomes of those who do remain poorly characterized.Methods: Using USRDS and SRTR data, we compared access…
  • 2015 American Transplant Congress

    MELD/PELD 35+ Candidates Benefit from Regional Sharing

    E. Edwards,1 A. Harper,1 R. Hirose,2 D. Mulligan.3

    1Research, UNOS, Richmond, VA; 2Divsion of Transplant, UCSF Medical Center, San Francisco, CA; 3Department of Surgery, Yale New Haven Hospital, New Haven, CT.

    Background: Based on a proposal from the Liver and Intestinal Organ Transplantation Committee, the OPTN implemented regional sharing for MELD/PELD 35+ candidates on June 18,…
  • 2015 American Transplant Congress

    Psychiatric Recommendations for Patients Pursing Kidney Transplantation

    M. Jesse, A. Eshelman, T. Rosetti, M. Abouljoud, J. Denny, A. Patel, D. Kim.

    Transplant Institute, Henry Ford Health System, Detroit, MI.

    Introduction: End-stage renal disease patients have high rates of psychiatric and cognitive pathologies. Despite this, renal transplant candidates do not routinely undergo comprehensive psychiatric evaluation.…
  • 2015 American Transplant Congress

    Belatacept-Treated Patients Had Better Graft Survival at 7-Years Post-Transplant Compared With Cyclosporine-Treated Patients: Final Results from BENEFIT

    F. Vincenti,1 J. Grinyó,2 L. Rostaing,3 K. Rice,4 S. Steinberg,5 M. Moal,6 M. Polinsky,7 U. Meier-Kriesche,7 C. Larsen.8

    1Univ of Calif, San Francisco; 2Univ Hosp Bellvitge, Barcelona, Spain; 3Univ Hosp and INSERM U563,IFR-BMT, Toulouse, France; 4Baylor Univ Med Ctr, Dallas; 5Sharp Memorial Hosp, San Diego; 6Hôp de La Cavale Blanche, Brest, France; 7BMS, Lawrenceville; 8Emory Univ Transpl Ctr, Atlanta.

    Background: At 3yrs, improvement in renal function was seen in kidney transplant recipients treated with belatacept (bela) vs cyclosporine (CsA) in BENEFIT. Here we report…
  • 2015 American Transplant Congress

    Epigenetic Reprogramming of Murine Cytomegalovirus Immediate Early Genes Induced By Renal Transplantation

    M. Hummel,1 X.-F. Liu,1 C. Jie,1 Z. Zhang,1 S. Yan,1 J.-J. Wang,1 S. Kurian,2 D. Salomon,2 M. Abecassis.1

    1Comprehensive Transplant Center, Northwestern University, Chicago, IL; 2Dept of Molecular and Experimental Medicine, The Scripps Research Institute, LaJolla, CA.

    Background: Reactivation of latent CMV is a significant infectious complication in solid organ transplant recipients. MCMV is a valuable model for studying molecular mechanisms controlling…
  • 2015 American Transplant Congress

    Correlates of Clinical Course of Polyomavirus BK Infection With Long-Term Outcome of BK Virus-Associated Nephropathy in Renal Transplant Patients

    G. Huang, C.-X. Wang, J.-G. Fei, J. Qiu, S.-X. Deng, J. Li, G.-D. Chen, Q. Fu, R.-H. Deng, L.-Z. Chen.

    Department of Organ Transplantation, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

    Background: Identification of risk factors for the long-term outcome of BK virus (BKV) -associated nephropathy(BKVAN) may improve renal transplant outcome. Methods: Between 2006 and 2014,…
  • 2015 American Transplant Congress

    Histologic Findings in Pre-transplant AT1Rab + ve Patients Point to an Increase in Sub-Intimal Fibrosis During Acute Rejection and in 12 mo. Protocol Renal Graft Biopsies

    A. González-Almada, J. Arreola-Guerra, E. Cuevas, M. Vilatoba, A. Contreras, A. Sanchez-Cedillo, J. Alberu, N. Uribe-Uribe.

    1Transplantation, 1aNephrology-Mineral Metabolism, 1bPathology, Inst Nal de Ciencias Medicas y Nutricion SZ, Mexico City, Distrito Federal, Mexico.

    Previous reports have described an increase in arteritis during acute rejection (AR) in angiotensin II type 1 receptor antibody (AT1Rab) positive (ve+) kidney transplant recipients…
  • 2015 American Transplant Congress

    Post-Transplant Recurrence of Calcium Oxalate Crystals in Primary Hyperoxaluria Type 1 Detected by Surveillance Biopsies: Incidence, Risk Factors, and Effect on Graft Function

    L. Cornell, N. Pamidi, R. Mehta, M. Stegall, E. Lorenz, J. Heimbach, D. Milliner.

    Mayo Clinic, Rochester, MN.

    Background: Primary hyperoxaluria type 1 (PH1) is a rare metabolic defect that results in oxalate over-production by the liver and leads to renal disease due…
  • 2015 American Transplant Congress

    Pediatric Living Donor Liver Transplantation at KFSH&RC – Implementation of the Laparoscopic Retrieval in a High Volume Center

    M. Boehnert, M. Shagrani, T. Al Goufi, D. Broering.

    Organ Transplant Centre, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.

    Since the first successful pediatric liver transplantation was performed in 1967 the survival rate increased from 30 % to currently above 90 %. This is…
  • 2015 American Transplant Congress

    Isolated Microcirculation Inflammation Negatively Impacts Renal Graft Function at 5 Years

    A. Chapelet,1 M. Touzot,1 M. Fournier,2 A. Cesbron,3 K. Renaudin,4 A. Moreau,4 E. Morelon,5 D. Anglicheau,6 M. Giral.1

    1Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France; 2EA 4275 SPHERE—Biostatistics, Pharmacoepidemiology and Subjective Measures in Health Sciences, University of Nantes, Nantes, France; 3Etablissement Français du Sang (EFS), Nantes, France; 4Service d'Anatomie et Cytologie Pathologiques, CHU Nantes, Nantes, France; 5Service de Néphrologie, Transplantation et Immunologie Clinique, Hôpital Edouard Herriot, Lyon, France; 6Service de Transplantation Rénale et de Soins Intensifs, Hôpital Necker, Paris, France.

    BACKGROUND: Microcirculation inflammation (MI, ie: glomerulitis (g) and peritubular capillaritis (ptc)) associated with anti-HLA Donor Specific Antibody (DSA) with or without C4d deposits in ptc…
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