Am J Transplant, Volume 5, Suppl 3 Archives - Page 142 of 170 - ATC Abstracts

2015 American Transplant Congress
Resolution of Glomerular Fibrin Thrombi in Deceased Donor Kidneys
R. Batra,¹ M. Smith,³ L. Thomas,² H. Khamash,² A. Moss,² J. Huskey,² A. Singer,¹ A. Mathur,¹ N. Katariya,¹ K. Reddy,¹ R. Heilman.²
¹Transplant Surgery, Mayo Clinic, Phoenix, AZ; ²Transplant Nephrology, Mayo Clinic, Phoenix, AZ; ³Pathology, Mayo Clinic, Phoenix, AZ.
BackgroundDeceased donor kidneys with Glomerular Fibrin Thrombi (GFT) are frequently discarded, but these kidneys may offer an opportunity to increase deceased donor organs. Our aim…
2015 American Transplant Congress
Regional Variations: Liver Transplant Tourism Within the US
C. Frenette,¹ A. Harper,² R. Schaffer,¹ J. Fisher,¹ A. Baquerizo,¹ C. Marsh.¹
¹Department of Organ Transplantation, Scripps Clinic/Green Hospital, La Jolla, CA; ²United Network for Organ Sharing, Richmond, VA.
Aim: Given the current geographic disparities in average MELD scores at liver transplantation (OLT), there is increasing interest in patients who travel for OLT and…
2015 American Transplant Congress
"In-House" Controlled Oxygenated Rewarming After Initial Static Cold Storage: First Clinical Application in Marginal Donor Livers
D. Hoyer,¹ Z. Mathé,¹ A. Gallinat,¹ A. Canbay,² J. Treckmann,¹ U. Rauen,³ A. Paul,¹ T. Minor.⁴
¹General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany; ²Gastroenterology and Hepatology, University Hospital Essen, Essen, Germany; ³Institute of Physiological Chemistry, University Hospital Essen, Essen, Germany; ⁴Surgical Research Division, University Hospital Bonn, Bonn, Germany.
IntroductionControlled oxygenated rewarming of cold stored livers by machine perfusion demonstrated a strong protective effect in preclinical studies. Here we report on the first clinical…
2015 American Transplant Congress
AAV-Mediated TIMP-1 Gene Therapy Ameliorates Hepatic Ischemia/Reperfusion Injury
S. Duarte, T. Fujii, G. Lipshutz, R. Busuttil, A. Coito.
The Dumont-UCLA Transplant Center, Los Angeles.
Matrix metalloproteinase-9 (MMP-9) is a key mediator of leukocyte migration across vascular barriers in hepatic ischemia/reperfusion injury (IRI). Tissue inhibitor of metalloproteinase-1 (TIMP-1) is the…
2015 American Transplant Congress
Can MitoQ Improve Renal and Mitochondrial Function Following Cold Storage and Transplantation?
L. MacMillan-Crow,¹ N. Parajuli,¹ D. Borja-Cacho.
¹Pharmacology/Toxicology, Univ. of Arkansas for Medical Sciences, Little Rock, AR; ²Surgery, Univ. of Arkansas for Medical Sciences, Little Rock, AR.
The overall goal of this study is to further evaluate the effectiveness of a potential new therapy designed to minimize damage during cold preservation, increase…
2015 American Transplant Congress
A Single Center Comparison of Various BK Viremia Elimination Protocols
Y. Qazi, K. Lee, B. Duong, R. Dhawan, L. Shinn, L. Aguirre, C. Parke, C. Wong, S. Alexopoulos, D. Olson, M. Smogorzewski.
Division of Transplantation, University Of Southern California. Keck Med Center, Los Angeles, CA.
Aim BK infection remains a significant complication post kidney transplantation. Best practices in BK management have evolved over time. The purpose of the study was…
2015 American Transplant Congress
hTERT, BICD1 and Chromosome 18 Polymorphisms Affecting Telomere Length Are Associated With Kidney Transplantation Outcome
L. Domanski,¹ K. Kloda,¹ K. Safranow,² A. Drozd,³ K. Ciechanowski,¹ A. Ciechanowicz.⁴
¹Clinical Department of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland; ²Department of Biochemistry and Medical Chemistry, Pomeranian Medical University in Szczecin, Szczecin, Poland; ³Department of Biochemistry and Human Nutrition, Pomeranian Medical University in Szczecin, Szczecin, Poland; ⁴Department of Laboratory Diagnostics and Molecular Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland.
Telomere length (TL) has been analyzed in regard to cell senescence and ageing of animals and humans, including age-related diseases. There have been also attempts…
2015 American Transplant Congress
Incorporating Markers of Donor Organ Intrinsic Biology Into Donor Quality Evaluation
J. Suh, K. Archer, L. Gallon, I. McConell, A. King, D. Maluf, V. Mas.
UVA, Charlottesville, VA; Northwestern University, Chicago, IL; VCU, Richmond, VA.
Background. We aimed to identify a reliable composite scoring system (clinical / biological) to evalute organ quality and predict outcomes post-kidney transplantation (KT).Methods. 233 deceased…
2015 American Transplant Congress
Perioperative Bacterial Colonization and Postoperative Urinary Tract Infection in Kidney Transplant Recipients
A. Han,¹ C. Choi,¹ S.-I. Min,¹ S.-K. Min,¹ S. Kim,² M. Park,³ J. Ha.¹
¹Department of Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea; ²Department of Surgery, Myongji Hospital, Goyang-si, Gyeonggi-do, Republic of Korea; ³Korean Organ Donation Agency, Seoul, Republic of Korea.
Background. Urinary tract infection (UTI) is the most common infection after kidney transplantation, and one of the source of the infection is thought to be…
2015 American Transplant Congress
The Differential Effect of HLA-DQ Mismatching on Renal Allograft Survival in Zero HLA-A,B,DR Mismatched Deceased Donor Transplants
M. Casey,¹ X. Wen,¹ S. Rehman,¹ A. Santos,¹ S. Goldstein,¹ K. Andreoni,¹ B. Kaplan,² K. Womer.¹
¹University of Florida, Gainesville; ²University of Kansas, Kansas City.
The role of HLA-DQ matching in renal graft survival is not well understood and difficult to interpret in the presence of other HLA antigen mismatches.…