ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Low Dose Valganciclovir Prophylaxis Following Renal Transplantation With Steroid Free Immunosuppression

    J. Chen,1 A. Shah,2 M. Sauer,1 T. Taber,3 A. Sharfuddin,3 M. Yaqub,3 D. Mishler,3 J. Powelson,4 W. Goggins.4

    1Pharmacy, IU Health, Indianapolis; 2Surgery, Thomas Jefferson University, Philadelphia; 3Nephrology, Indiana University School of Medicine, Indianapolis; 4Surgery, Indiana University School of Medicine, Indianapolis.

    AST ID guidelines recommend a valganciclovir (VGCV) prophylaxis dose of 900 mg daily for patients with CrCL > 60 mL/min with reduced dose for renal…
  • 2015 American Transplant Congress

    Utilization of Medicare Part D Among Transplant Recipients

    M. Chisholm-Burns, C. Spivey.

    University of Tennessee College of Pharmacy, Memphis, TN.

    Purpose: As cost is a critical barrier to medication access among transplant recipients, Medicare Part D represents a key strategy in medication acquisition. Due to…
  • 2015 American Transplant Congress

    Impact of Pretransplant Pregnancy On Immunization and Immunologic Outcome in Kidney Transplantation

    O. Staeck,1 D. Khadzhynov,1 S. Kreimer,1 E. Rajakangas,1 C. Schönemann,2 N. Lachmann,2 K. Budde,1 F. Halleck.1

    1Nephrology, Charité Universitätsmedizin, Berlin, Germany; 2Zentrum für Transfusionsmedizin, Charité Universitätsmedizin, Berlin, Germany.

    BACKGROUND:The detailed impact of pretransplant pregnancy on HLA alloimmunization and outcome after kidney transplantation is so far not well known.PATIENTS AND METHODS:A retrospective single center…
  • 2015 American Transplant Congress

    Clinical Subclassifiation of ABMR Phenotypes: Recognizing Variation in Presentation

    P. Halloran, M. Lopez, I. Salazar, J. Chang.

    Alberta Transplant Applied Genomics Centre, Edmonton, Canada.

    The diagnosis of ABMR in kidney transplants is based on ptc-, g- and cg-lesions in biopsies and donor-specific antibody (DSA). To recognize the actual phenotypes…
  • 2015 American Transplant Congress

    Pediatric Liver Transplantation for Metabolic Diseases: Analysis of Children's Hospital of Pittsburgh (CHP) and United Network for Organ Sharing (UNOS) Databases

    A. Ganoza, B. Shneider, R. Sindhi, K. Soltys, G. Bond, G. Vockley, Q. Sun, G. Mazariegos.

    Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.

    Purpose: To analyze long term patient survival outcomes after primary LTx for metabolic disease in children <21 years at CHP (1981-2014) and the multi-center UNOS…
  • 2015 American Transplant Congress

    A Single Center Study of the Implementation Costs of the New Kidney Allocation System

    C. Bostic, T. Stern, S. Niederhaus, J. Bromberg, D. Leeser.

    Transplantation, University of Maryland Medical Center, Baltimore, MD.

    Background: Changes to the Kidney Allocation System (KAS) required transplant programs to utilize resources to prepare for its implementation. A complex strategy was developed which…
  • 2015 American Transplant Congress

    Passive Administration of Antibodies to Cardiac Myosin Immediately Following Syngenic Cardiac Transplantation Result in Rejection

    M. Sharma, M. Gunasekaran, N. Benshoff, W. Liu, A. Gelman, T. Mohanakumar.

    Surgery, Washington Univ Sch of Med, St. Louis, MO.

    Introduction: Auto-immune responses to cardiac myosin, a heart specific protein has been proposed to be a target auto-antigen resulting in cardiac allograft vasculopathy following transplantation.…
  • 2015 American Transplant Congress

    Renal Tubular Dysfunction Following Donor Nephrectomy and Its Impact On Residual Kidney Function

    Z. Ahmed,1 C. Rooney,3 C. Turner,2 N. Dalton,2 N. Kessaris,1 N. Mamode.1

    1Renal and Pancreatic Transplantation, Guy's Hospital, London, United Kingdom; 2Wellchild Laboratory, St Thomas' Hospital, London, United Kingdom; 3Faculty of Medicine, King's College London, London, United Kingdom.

    Background: Recent publications have described an increasing incidence of end stage renal disease amongst kidney donors. This highlights the paucity of knowledge which exists in…
  • 2015 American Transplant Congress

    Engagement of the Vasopressin Receptor On Hepatocytes Protects Liver from Ischemia-Reperfusion Injury Via the WNT-β-Catenin-SGK1-FOXO Pathway

    X. Liu,1 T. Billiar,2 R. Tao.1

    1Department of Hepatobiliary-Pancreatic Surgery, Zhejiang Provincial Peoples' Hospital, Hangzhou, Zhejiang Province, China; 2Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.

    The synthetic vasopressin analogue, terlipressin, has been extensively used in the management of certain complications associated with end-stage liver diseases (ESLDs), however concerns have been…
  • 2015 American Transplant Congress

    Long-Term Efficacy and Safety of an EVR- Vs. an MMF-Based Regimen After Pediatric Kidney Transplantation (KTX): A Case-Control Study Within the CERTAIN Registry

    L. Pape,1 T. Ahlenstiel-Grunow,1 B. Hoecker,2 M. Bald,3 K. Kruppka,2 B. Toenshoff,2 L. Brunkhorst.1

    1Pediatric Nephrology, Hannover Medical School, Hannover, NDS, Germany; 2Pediatric Nephrology, University Children's Hospital, Heidelberg, BW, Germany; 3Pediatric Nephrology, Olgahospital, Stuttgart, BW, Germany.

    Background: Only short-term trials using everolimus (EVR) in children after KTX have been published. Hereby we present 4 year data on low-dose ciclosporin A (CsA),…
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