Am J Transplant, Volume 5, Suppl 3 Archives - Page 137 of 170 - ATC Abstracts

2015 American Transplant Congress
Outcome of Bortezomib/Plasmapheresis for the Sensitized Patient Awaiting Heart Transplant
J. Patel, N. Reinsmoen, M. Kittleson, D. Dilibero, F. Liou, D. Chang, M. Hamilton, L. Czer, F. Esmailian, J. Kobashigawa.
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: Allosensitization of patients (pts) awaiting heart transplantation is a significant challenge as it prolongs the time to transplant, increases wait-list mortality and increases risk…
2015 American Transplant Congress
Aquaporin 4 Blockade Is a Novel Strategy Targeting Ischemia/Reperfusion Injury in Heart Transplantation
K. Ayasoufi,¹ N. Kohei,¹ G. Farr,² P. McGuirk,² M. Pelletier,² R. Fairchild,¹ A. Valujskikh.¹
¹Immunology, Cleveland Clinic, Cleveland, OH; ²Aeromics, LLC, Cleveland, OH.
Aquaporin 4 (AQP4) belongs to the family of small integrin transmembrane proteins that are highly permeable to water. It was recently shown that human and…
2015 American Transplant Congress
Impact of Community Risk on Early Hospital Readmission Following Kidney Transplant
E. King,¹ L. Kucirka,¹ M. McAdams-DeMarco,^1,2 A. Massie,^1,2 J. Schold,³ D. Segev.^1,2
¹Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD; ²Epidemiology, Johns Hopkins University, School of Public Health, Baltimore, MD; ³Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.
Background: Early hospital readmission (EHR) is associated with increased morbidity, mortality, and cost in kidney transplantation (KT). Community risk may be associated with EHR above…
2015 American Transplant Congress
Robotic Kidney Transplantation With Regional Hypothermia: Results from a Prospective Two-Arm Non-Randomized Controlled Trial (Ideal Phase 2b)
R. Ahlawat,¹ A. Sood,² P. Ghosh,¹ V. Kher,¹ M. Bhandari,² M. Menon.²
¹Institute of Kidney and Urology, Medanta, the Medicity, Gurgaon, Haryana, India; ²Vattikuti Urology Institute, Henry Ford Hospital, Detroit, MI.
ObjectivesMinimally-invasive approaches to kidney transplantation are up-coming. We recently developed and described a novel technique of robotic KT (RKT) using intra corporeal graft cooling. Here,…
2015 American Transplant Congress
Donor Specific Antibodies (DSA) Increase the Risk for Rejection After Pancreas Transplantation Qithout Negatively Impacting Survival
M. Marquez, M. Dib, G. Sapisochin, J. Laurence, A. Barbas, F. Bazerbachi, A. Norgate, M. Selzner, P. Greig, I. McGilvray, M. Cattal.
Multi-Organ Transplant, University Health Network, Toronto, ON, Canada.
Donor-specific antibodies (DSA) have been associated with increased rejection and lower kidney transplant survival. The impact of DSA on pancreas transplant outcomes in patients with…
2015 American Transplant Congress
TGFβ Production By B Cells Is Critical for Transplant Tolerance Induction
J. Kim,¹ W. Liu,^1,2 L. Liu,^1,2 K. Lee,¹ R. Stott,¹ H. Yeh,¹ J. Markmann.¹
¹Surgery, Massachusetts General Hospital / Harvard Medical School, Boston, MA; ²Surgery, Chengdu Military General Hospital, Chengdu, Sichuan, China.
Regulatory B cells (Bregs) have been shown to play a critical role in immune homeostasis and in autoimmunity models. We have recently demonstrated that combined…
2015 American Transplant Congress
Process Deviation Tracking and Analysis in an Organ Procurement Organization
B. Schleich,¹ S. Yoon,¹ M. Khasawneh,¹ K. Srihari,¹ H. Irving,² A. Friedman.
¹Systems Science and Industrial Engineering, State University of New York at Binghamton, Binghamton, NY; ²New York Organ Donor Network, New York, NY.
"It is common practice for Organ Procurement Organizations (OPOs) to report, collect and track issues and problems occurring during the organ donation process. We labeled…
2015 American Transplant Congress
MicroRNA let-7i Targeting IL-10 Via JAK1-STAT3 Signal Pathway Regulates Dendritic Cells Maturation Subsequently Induces Cardiac Allograft Tolerance
J. Wu,^2,3 X. Jin,¹ Y. Sun,^2,3 X. Liu,^2,3 D. Chi,^2,3 B. Yu.^2,3
¹Thoracic Surgery, The Third Affiliated Hospital of Harbin Medical University, Harbin, China; ²Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China; ³Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Background: Our previous study demonstrated that microRNA (MiR) let-7i could regulate dendritic cells (DCs) maturation and functional state via targeting SOCS1. In this study, we…
2015 American Transplant Congress
Development of a Targeted Genetic Renal Disease Panel With NexGen Sequencing for Unbiased Testing of Living Kidney Donors for Genetic Kidney Disease
C. Thomas,¹ Z. Stewart,³ A. Mansilla,² S. Mason,² A. Kwitek,² C. Campbell,² R. Smith,^1,2 R. Smith.^1,2
¹Internal Medicine, University of Iowa, Iowa City, IA; ²Institute of Human Genetics, University of Iowa, Iowa City, IA; ³Surgery, University of Iowa, Iowa City, IA.
Recent studies indicate that living donors biologically related to their transplant recipient may be at higher risk of ESRD compared to unrelated donors, possibly secondary…
2015 American Transplant Congress
The Extended Toronto Criteria for Transplantation for Hepatocellular Carcinoma. A Validation Study
G. Sapisochin, N. Goldaracena, J. Laurence, M. Dib, A. Barbas, A. Ghanekar, L. Lilly, E. Renner, M. Selzner, M. Cattral, I. McGilvray, D. Grant, P. Greig.
Multi-Organ Transplant, Toronto General Hospital. University of Toronto, Toronto, ON, Canada.
Liver transplant (LT) listing criteria for patients with hepatocellular cancers (HCC) that exceed the Milan criteria are still controversial. At the University of Toronto, we…