Am J Transplant, Volume 5, Suppl 3 Archives - Page 136 of 170 - ATC Abstracts

2015 American Transplant Congress
Birth Weight as a Marker of Nephron Mass: Predicting Living Kidney Donor Outcomes
T. Schachtner,^1,2 P. Reinke.^1,2
¹Nephrology and Internal Intensive Care, Charité Campus Virchow Clinic, Berlin, Germany; ²Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany.
It has been demonstrated that low birth weights give rise to a reduction in nephron number and low glomerular size in the postnatal kidney. Oligonephropathy…
2015 American Transplant Congress
Matching of Recipient and Donor Age Is the Most Powerful Risk Factor Affecting to Long-Term Graft Survival and Function
J. Lee,^1,2 Y. Lee,² J. Lee,^1,2 D. Joo,^1,2 K. Huh,^1,2 S. Kim,^1,2 Y. Kim,^1,2 M. Kim.^1,2
¹Department of Tranplantation Surgery, Yonsei University Health System, Seoul, Republic of Korea; ²The Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Republic of Korea.
Recipient age and donor age were typical non-immunologic parameters affecting to graft survival rate (GSR). Using more than 3,000 cases of living donor transplantation database…
2015 American Transplant Congress
Anti-Thymocyte Globulin Induction in Infected Mechanical Circulatory Support Patients: Is It Safe?
G. Jamero, J. Moriguchi, L. Czer, M. Kittleson, S. Siddiqui, F. Liou, D. Arman, L. Lam, D. Chang, P. Zakowski, J. Kobashigawa.
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: The use of mechanical circulatory assist devices (MCSD) have been increasing over the past several years. Driveline infections (DLI) are one of the most…
2015 American Transplant Congress
Effect of Donor Age On Pancreas Transplantation Outcome
A. Rathnasamy Muthusamy,¹ G. Vrakas,¹ S. Mittal,¹ S. Reddy,¹ I. Quiroga,¹ J. Gilbert,¹ R. Ploeg,² E. Sharples,¹ S. Sinha,¹ A. Vaidya,¹ P. Friend.²
¹Transplant Surgery, Churchill Hospital, Oxford, United Kingdom; ²Nuffield Department of Surgery, University of Oxford, Oxford, United Kingdom.
The global increase in the average donor age over the last decade has resulted in widespread acceptance of pancreases from older donors for transplantation. This…
2015 American Transplant Congress
Endovascular Salvage of a Pancreas Allograft Having Developed a Large AV Fistula and Aneurysm
N. Katariya,¹ R. Batra,¹ A. Moss,¹ K. Reddy,¹ A. Mathur,¹ E. Huettl,² S. Naidu,² A. Singer.¹
¹Surgery, Mayo Clinic, Phoenix, AZ; ²Radiology, Mayo Clinic, Phoenix, AZ.
We present an unusual case of a late, large pancreas allograft arteriovenous fistula and aneurysm rescued from threatened rupture or need for transplant pancreatectomy by…
2015 American Transplant Congress
Application of the Clavien Classification of Surgical Complications to Robotic Kidney Transplantation
R. Garcia Roca, C. Martinez Parra, I. Tzvetanov, H. Jeon, E. Benedetti, J. Oberholzer.
Surgery, Transplant Division, University of Illinois Hospital and Health Sciences, Chicago, IL.
INTRODUCTIONThe Clavien-Dindo Classification of complications after a surgical procedure is an objective measure of outcomes and serves as a comparison tool to evaluate procedure safety…
2015 American Transplant Congress
DNA Methylation of the IFNγ Promoter in CD8+ T Cell Subsets Is Modulated by CMV Infection but not by Alloreactivity in Kidney Transplantation Patients
K. Boer,¹ E. de Wit,¹ L. Hofland,² M. Betjes,¹ C. Baan.¹
¹Internal Medicine - Nephrology and Transplantation, Erasmus University Medical Center, Rotterdam, Netherlands; ²Internal Medicine - Endocrinology, Erasmus University Medical Center, Rotterdam, Netherlands.
Introduction DNA methylation plays a critical role in the function of cells, including cells of the immune system. Little is known about the methylation status…
2015 American Transplant Congress
Frequencies of CD4⁺25^hiFoxp3⁺T Cells in Long-Term Follow-Up of Sirolimus-Converted Kidney Transplant Recipients
O. Traitanon,^1,2 A. Alvarado,¹ E. Tantisattamo,^1,2 A. Shetty,^1,2 M. Ansari,^1,2 J. Mathew,¹ J. Leventhal,¹ V. Mas,³ L. Gallon.^1,2
¹Comprehensive Transplant Center, Northwestern University, Chicago, IL; ²Medicine-Nephrology, Northwestern University, Chicago, IL; ³Surgery, University of Virginia, Charlottesville, VA.
Background: Tacrolimus(TAC) and Sirolimus(SRL) are commonly used immunosuppressive drugs in kidney transplantation. SRL has been shown to induce the expansion of regulatory T cells in…
2015 American Transplant Congress
Development and Validation of a Genotype Guided Tacrolimus Dosing Equation for African American (AA) Kidney Transplant Recipients
K. Sanghavi,¹ R. Brundage,¹ M. Miller,² D. Schaldt,³ A. Israni,³ W. Guan,⁴ W. Oetting,¹ R. Mannon,⁵ R. Remmel,¹ A. Matas,⁶ P. Jacobson.¹
¹College of Pharmacy, University of MN, Minneapolis, MN; ²Dept of Psychology, University of MN, Minneapolis, MN; ³Minneapolis Medical Research Foundation, Hennepin County Medical Center, Minneapolis, MN; ⁴Dept of Biostatistics, University of MN, Minneapolis, MN; ⁵Dept of Nephrology, University of AL, Birmingham, AL; ⁶Dept of Surgery, University of MN, Minneapolis, MN.
Tacrolimus (tac) has a strong exposure-response relationship with high inter-individual variability in troughs and dose. Tac dose requirements for AA patients are higher than Caucasians,…
2015 American Transplant Congress
CMV prevalence in Mauritian and Indonesian Cynomolgus Macaques: Significance in Transplantation and CMV Disease Models
K. Premanand,¹ E. Szilagyi,¹ J. Yu,¹ R. Patel,¹ A. Antony,¹ M. Willman,² D. Berman-Weinberg,² D. Han,² A. Vaidya,³ E. Silva,³ K. McHenry,³ D. Salomon,⁴ N. Kenyon,² A. Bartholomew.¹
¹University of Illinois, Chicago; ²Univerisity of Miami, Miami; ³University of Illinois, Urbana; ⁴Scripps, San Diego.
Despite the finding that most macaques express high serologic titers of anti-CMV antibody, susceptibility to disease appears to be variable post-transplant. This observation led us…