Am J Transplant, Volume 5, Suppl 3 Archives - Page 134 of 170 - ATC Abstracts

2015 American Transplant Congress
Establishment of Diabetes Modeling in Common Marmoset
W. Yuan,¹ S. Fukuda,¹ T. Inoue,² D. Chujo,¹ H. Okochi,¹ E. Sasaki,² M. Shimoda.¹
¹National Center for Global Health and Medicine, Tokyo, Japan; ²Central Institute for Experimental Animals, Kawasaki, Japan.
Background:Diabetic nonhuman primates (NHPs) are considered as the good models for both diabetes mellitus research and islet transplantation research safely into clinical applications. However, there…
2015 American Transplant Congress
Ischemia-Induced Endoplasmic Reticulum Stress Regulates Autophagy to Determine the Severity of Liver Ischemia Reperfusion Injury
H. Zhou,^1,2 J. Zhu,¹ S. Yue,¹ R. Busuttil,¹ J. Kupiec-Weglinski,¹ Y. Zhai.¹
¹The Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA; ²Liver Transplant Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Both endoplasmic reticulum (ER) stress and autophagy have been implicated in the pathogenesis of ischemia and reperfusion injury (IRI). As essential cellular stress responses against…
2015 American Transplant Congress
Enhancing Kidney Function Following DCD Donation With Thrombolytic Therapy: A Preliminary Report of a Multicenter Prospective Quasi-Blinded Randomized Trial
K. Woodside,¹ D. Goldfarb,² J. Rabets,² E. Sanchez,¹ D. Lebovitz,³ J. Schulak,¹ J. Fung,² B. Eghtesad.²
¹Transplant Institute, University Hospitals Case Medical Center, Cleveland, OH; ²Transplant Center, Cleveland Clinic, Cleveland, OH; ³LIfebanc, Cleveland, OH.
Kidneys from donors following cardiac death (DCD) are at risk for inferior outcomes, possibly due to microthrombi and additional warm ischemia. We describe an organ…
2015 American Transplant Congress
100 Protocol Renal Allograft Biopsies at 10 Years: First Look at the Tacrolimus Era
M. Stegall,¹ W. Park,¹ F. Cosio,² L. Cornell.³
¹Transplant Surgery, Mayo Clinic, Rochester, MN; ²Medicine, Mayo Clinic, Rochester, MN; ³Laboratory Medicine, Mayo Clinic, Rochester, MN.
This study examined late renal allograft injury in the Tacrolimus era in 10-yr protocol biopsies (Bx).Methods One hundred 10-yr protocol allograft bx were assessed using…
2015 American Transplant Congress
Morphometry of the Epithelial-Mesenchymal Transition (EMT) in Subsequent Biopsies from Transplanted Kidney
R. Świder, A. Perkowska-Ptasińska, A. Stachurska, J. Fabijańska-Mitek, R. Zagożdżon, S. Gruca, J. Gołąb, M. Durlik.
Department of Transplantation Medicine, Medical University, Warsaw, Poland; Department of Transplantation Medicine, Medical University, Warsaw, Poland; Department of Immudohaematology, Centre of Postgraduate Medical Education, Warsaw, Poland; Department of Immudohaematology, Centre of Postgraduate Medical Education, Warsaw, Poland; Department of Immunology, Medical University, Warsaw, Poland; Department of Immunology, Medical University, Warsaw, Poland; Department of Immunology, Medical University, Warsaw, Poland; Department of Transplantation Medicine, Medical University, Warsaw, Poland.
EMT plays the principal role in the pathogenesis of IF/TA as a consequence in the failure of a transplanted kidney. Many facts suggest that the…
2015 American Transplant Congress
Down-Regulation of Autophagy Correlates With Increased Apoptosis in the Kidney, But Not in the Liver, of Brain Dead Rats
A. van Erp,¹ R. Rebolledo,³ P. Ottens,¹ J. Pirenne,² H. Leuvenink,¹ J.-P. Decuypere.²
¹Department of Surgery, University Medical Center Groningen, Groningen, Netherlands; ²Department of Microbiology and Immunology, Catholic University Leuven, Leuven, Belgium; ³Department of Surgery, University of Chile, Santiago, Chile.
Organs from brain dead donors have inferior quality and show higher rejection rates after transplantation compared to living donors. Brain death (BD) in the donor…
2015 American Transplant Congress
Short-Term QOL After Live Liver Donation: A New York Center for Liver Transplantation (NYCLT) Report
D. LaPointe Rudow,¹ S. DeLair,² S. Florman,¹ J. Guarrera,³ M. Kinkhabwala,⁴ M. Orloff,⁵ Y. Wu,⁶ L. Teperman.⁷
¹Mount Sinai Medical Center, New York, NY; ²New York Center for Liver Transplantation, Albany, NY; ³New York Presbyterian Hosptial, New York, NY; ⁴Montefiore Medical Center, Bronx, NY; ⁵University of Rochester Medical Center, Rochester, NY; ⁶Westchester Medical Center, Valhala, NY; ⁷New York University Hospitals Center, New York, NY.
Introduction: LDLT is an option for selective patients, especially in regions with less opportunity for deceased donors. New York State (NYS) has the most LDLT…
2015 American Transplant Congress
Incisional Herniation Following Hand Assisted Laparoscopic Donor Nephrectomy: Incidence, Impact and Aetiology
Z. Ahmed, I. Mosca, M. Dirix, R. Tamburrini, N. Kessaris, N. Mamode.
Renal and Pancreatic Transplantation, Guy's Hospital, London, United Kingdom.
Introduction: Living kidney donor demographics, perioperative outcomes and data on renal function is recorded by national mandate. However other longer term and potentially significant surgical…
2015 American Transplant Congress
Evaluation of Geographically Distant Living Kidney Donors: A Barrier to Living Donation?
F. Weng, N. Dhillon, L. Davis, R. Goldberg, A. Patel, K. Tibaldi, M. Morgievich, S. Mulgaonkar.
Renal & Pancreas Transplant Division, Saint Barnabas Medical Center, Livingston, NJ.
Introduction: Living kidney donors often live far from the recovering transplant center where they donate. We sought to determine (1) characteristics of these geographically distant,…
2015 American Transplant Congress
Acute Kidney Injury After Lung Transplantation – Incidence, Risk Factors and Mechanisms
F. Gueler,¹ G. Warnecke,⁵ M. Peperhove,² M.-S. Jang,¹ C. Schroeder,³ S. Tewes,² B. Wiese,⁶ C. Fegbeutel,⁵ R. Lichtinghagen,⁷ B. Jüttner,⁸ F. Wacker,² D. Hartung,² B. Akerstrom,⁴ M. Gram,⁴ H. Haller,¹ A. Haverich,⁹ K. Hueper.²
¹Nephrology, Hannover Medical School, Hannover, Germany; ²Radiology, Hannover Medical School, Hannover, Germany; ³Proteomics, German Research Cancer Center, Heidelberg, Germany; ⁴Physiology, Lund University, Lund, Sweden; ⁵Thoracic and Cardiac Surgery, Hannover Medical School, Hannover, Germany; ⁶Medical Statistics, Hannover Medical School, Hannover, Germany; ⁷Laboratory Medicine, Hannover Medical School, Hannover, Germany; ⁸Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany; ⁹Cardiothoracic, Transplant and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Background: Acute kidney injury (AKI) is a frequent and severe complication after solid organ transplantation. In a retrospective analysis and afterwards in a prospective clinical…