2015 American Transplant Congress
Influence of CYP3A5 and ABCB1 Genotypes on Pharmacokinetics of Immediate and Prolonged Release Tacrolimus Preparations
Background. Tacrolimus is available in two formulations, immediate-release, (Prograf®) and prolonged -release formulation of tacrolimus (Advagraf®). Tacrolimus has a narrow therapeutic index with wide variation…2015 American Transplant Congress
Calcineurin Inhibitors (CNI) Minimization Associated With Mammalian Target of Rapamycin Inhibitors (i-mTOR) to Improve Renal Function in Renal Grafts from Uncontrolled Donation After Cardiac Death Donors (UDCDD)
INTRODUCTION: Ischemia injury in kidneys grafts from UDCDD could produce a poor renal function. Minimized blood levels of CNI associated with i-mTOR therapy could avoid…2015 American Transplant Congress
Significance of an Isolated Elevated PRA in Renal Transplantation
Houston Methodist Hospital, Houston, TX.
Transplant centers have traditionally discerned a patient's immunologic risk based on peak panel reactive antibody (PRA) levels. However, in a given patient, pre-transplant PRA may…2015 American Transplant Congress
Alpha-Fetoprotein as a Modifier of Anatomic Criteria for Transplantation of HCC Patients
Background:The current listing criteria (Milan, UCSF) for Orthotropic Liver Transplants (OLT) in hepatocellular carcinoma (HCC) patients emphasize the anatomic features of the tumor such as…2015 American Transplant Congress
Clinical Impact of 18F-FDG-PET/CT in Living Donor Liver Transplantation for Advanced Hepatocellular Carcinoma
Liver Cancer Center, National Cancer Center, Goyang, Korea.
Background: The relevant number of patients with hepatocellular carcinoma (HCC) beyond the Milan criteria has undergone living donor liver transplantation (LDLT). However, the prognostic factors…2015 American Transplant Congress
Eosinophilic Gastrointestinal Disease in Pediatric Liver and Kidney Transplant Recipients
1Pediatrics, Northwestern University, Chicago; 2Pathology, Northwestern University, Chicago.
Eosinophilic gastrointestinal disease (EGID) has been associated with immunosuppression use in solid organ transplant recipients. However, its relationship to the post-transplant clinical course is unknown.…2015 American Transplant Congress
Is There a Difference in Patient and Graft Survival in Children Weighing <20 kg Versus Those Weighing >20 kg at the Time of Renal Transplantation?
Introduction: Renal transplantation (RTx) is the gold standard treatment modality for end-stage kidney disease. There are increased challenges in pediatric renal transplant recipients (pRTR) under…2015 American Transplant Congress
Rituximab: Summarizing the Intracacies of the Black Box Warning and Expenses in Transplantation
Department of Pharmacy, NewYork-Presbyterian Hospital, New York, NY.
Post-transplant use of rituximab has become common, yet is associated with significant safety concerns and cost. Hepatitis B virus (HBV) reactivation following rituximab therapy poses…2015 American Transplant Congress
Long-Term Results After Heart Transplantation – A Randomized Trial Comparing Tacrolimus Versus Cyclosporine A in Combination With Mycophenolate Mofetil After a Mean Duration of 15 Years
Purpose. Development of cardiac allograft vasculopathy (CAV), renal dysfunction and malignancies are the main risks due to long-term immunosuppressive therapy after heart transplantation (HTx). We…2015 American Transplant Congress
Low Dose Valganciclovir Prophylaxis Following Renal Transplantation With Steroid Free Immunosuppression
AST ID guidelines recommend a valganciclovir (VGCV) prophylaxis dose of 900 mg daily for patients with CrCL > 60 mL/min with reduced dose for renal…
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