ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    The Outcome of Carbapenemase-Producing Enterobacteriaceae (CPE) Infection in Adult Solid Organ Transplant Population at a University Teaching Hospital

    H. Sharma, A. El-Bakry, V. Venkat, S. Papachristos, P. Otilla, R. Dhanda, B. Forgacs, A. Tavakoli, R. Pararajasingam.

    Transplant Surgery, Manchester Royal Infirmary, Manchester, United Kingdom.

    BACKGROUND:Over the last decade CPE infection has been reported globally and is now endemic in healthcare facilities in many countries. There has been no report…
  • 2015 American Transplant Congress

    Pancreatic Islet Survival Under Confinement

    A. Rodriguez, S. Sigrist, E. Maillard.

    UMR DIATHEC EA 7294, Centre Européen d'Etude du Diabète, Strasbourg, France.

    The main advantage of cell therapy is the possibility to immune-isolate the graft in a device to avoid immune suppressive regimen. In islet transplantation field,…
  • 2015 American Transplant Congress

    Immune Rejection of iPS Cells Is Triggered By Gamete-Associated Proteins (GAPs)

    E.-M. Kim, G. Manzar, N. Zavazava.

    Internal Medicine, University of Iowa, Iowa City, IA; Internal Medicine, University of Iowa, Iowa City, IA; Internal Medicine, University of Iowa, Iowa City, IA.

    Induced pluripotent stem (iPS) cells have emerged as a new source for cell based therapies. However, the safety of iPS cells in autologous recipients has…
  • 2015 American Transplant Congress

    A Randomized Cross-Over Phase 3b Study of the Pharmacokinetics of Once-Daily Extended Release MeltDose® Tacrolimus (Envarsus® XR) Versus Twice-Daily Tacrolimus in African-Americans (ASERTAA)

    J. Trofe-Clark,1,2 D. Brennan,3 P. West-Thielke,4 M. Milone,5 M. Lim,2 R. Bloom.2

    1Pharmacy Services, Hospital of the University of Pennsylvania, Philadelphia; 2Renal Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia; 3Renal Division, Washington University, St. Louis; 4University of Illinois at Chicago, Chicago; 5Penn Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

    The CYP3A5*1 genotype, highly prevalent in African Americans (AA), commonly necessitates higher tacrolimus (tac) dose requirements and may hinder efforts to obtain therapeutic drug levels.…
  • 2015 American Transplant Congress

    Histology of Renal Allografts With DGF Provides Limited Prognostic Information

    S. Balasubramanian,1 A. Cherukuri,2 P. Prasad,1 R. Baker.1

    1Transplantation, Leeds Teaching Hospital, Leeds, United Kingdom; 2University of Pittsburgh, Pittsburgh.

    DGF has been shown to be associated with adverse graft outcomes in renal transplantation. However DGF is heterogeneous histologically and the impact of various histological…
  • 2015 American Transplant Congress

    Inflammation in Regions of Tubular Atrophy (IATR) Predicts Adverse Graft Outcome in Patients With Late Graft Dysfunction: A Multicenter Study

    J. Grande,1 R. Leduc,3 A. Matas.2

    1Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN; 2Surgery, University of Minnesota, Minneapolis, MN; 3Biostatistics, University of Minnesota, Minneapolis, MN.

    Purpose: Inflammation in regions of tubular atrophy (IATR) is a risk factor for late graft loss. However, IATR is associated with inflammation in non-atrophic regions…
  • 2015 American Transplant Congress

    Interstitial Fibrosis Is the Critical Determinant of Impaired Renal Function in Transplant Glomerulopathy

    D. Toki,1 H. Ishida,1 M. Okumi,1 T. Shimizu,1 H. Shirakawa,1 M. Inui,1 K. Omoto,1 K. Unagami,1 T. Kanzawa,1 K. Honda,2 J. Koike,3 K. Tanabe.1

    1Urology, Tokyo Women's Medical University, Tokyo, Japan; 2Pathology, Tokyo Women's Medical University, Tokyo, Japan; 3Pathology, Tama Hospital, Kanagawa, Japan.

    PURPOSE: Transplant glomerulopathy (TGP) represents chronic antibody-mediated injury in the glomerular capillaries after renal transplantation, and is the main cause of graft failure. TGP is…
  • 2015 American Transplant Congress

    A Retrospective Review of a Renal Sparing Protocol in Orthotopic Liver Transplantation

    B. Pierce,2 J. Levitsky,1,3 M. McLaughlin,2 C. Richardson.2

    1Department of Medicine, Northwestern Medicine, Chicago, IL; 2Pharmacy, Northwestern Medicine, Chicago, IL; 3Hepatology, Northwestern Medicine, Chicago, IL.

    Liver transplant recipients with pre-existing renal insufficiency are placed on a renal sparing protocol (RSP) consisting of delayed initiation of low-dose tacrolimus in addition to…
  • 2015 American Transplant Congress

    The Product of Donor Age and Preoperative MELD, D-MELD, Predicts Surgical Outcomes After LDLT, When Using Small Graft

    A. Tanemura, S. Mizuno, H. Kato, Y. Murata, N. Kuriyama, Y. Azumi, M. Kishiwada, M. Usui, H. Sakurai, S. Isaji.

    Hepatobiliary Pancreatic and Transplant Surgery, Mie University Graduate School of Medicine, Tsu, Japan.

    Background:Donor-recipient match is recognized as the factor well predicting recipient outcome in deceased donor liver transplantation. The aim of the present study is to evaluate…
  • 2015 American Transplant Congress

    Hispanic/Latino Disparities in Living Donor Kidney Transplantation – Role of a Culturally Competent Transplant Program

    E. Gordon, J. Lee, R. Kang, D. Ladner, A. Skaro, J. Holl, D. French, M. Abecassis, J. Caicedo.

    Northwestern University Feinberg School of Medicine, Chicago, IL.

    Background and objectives: Hispanic Americans face disparities in access to kidney transplantation, particularly living donor kidney transplantation (LDKT).Design, setting, participants, and measurements: Northwestern Medicine's® (NM)…
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