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American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Are AT1R Antibodies as Dangerous as HLA-DSAs in Renal Allografts?

    E. Cuevas, J. Arreola-Guerra, E. Hernandez-Mendez, I. Salcedo, M. Vilatoba, A. Contreras, A. Sanchez-Cedillo, J. Ramirez, D. de Rungs, J. Granados, L. Morales-Buenrostro, J. Alberu.

    1Transplantation, 1aNephrology-Mineral Metabolism, Inst Nal de Ciencias Medicas y Nutricion SZ, Mexico City, Distrito Federal, Mexico.

    Angiotensin II type 1 receptor antibodies (AT1Rab) have been associated with a significantly lower graft survival and a higher risk of acute rejection after kidney…
  • 2015 American Transplant Congress

    Repeat Donor HLA Mismatch Antigens and Kidney Transplant Outcome

    P. Lokhandwala,1 M. Wang,2 Z. Kadry,3 R. Shah,3 A. Jain,3 J. Gaspari,1 N. Ghahramani,4 C. Abendroth,1 H. Shike.1

    1Pathology, Penn State Hershey Medical Center, Hershey, PA; 2Public Health Sciences, Penn State College of Medicine, Hershey; 3Transplant Surgery, PSHMC, Hershey; 4Nephrology, PSHMC, Hershey.

    Background: Historically, poorer outcome has been reported in kidney re-transplant patients with repeat HLA mismatch antigens. Transplant practice has evolved. Risk of repeat mismatch antigen…
  • 2015 American Transplant Congress

    Impact of Pre-Transplant Panel Reactive Antibody Levels On Renal Graft Survival in Patients With Negative Cross-Match and No Donor Specific Antibody

    K. Jun,1 M. Kim,1 H. Kim,1 K. Park,2 S. Ahn,1 J. Hwang,1 S. Kim,1 S. Park,1 S. Kim,1 J. Kim,1 I. Moon.1

    1Vascular and Transplant Surgery, The Catholic University of Korea, Seoul, Korea; 2Vascular Surgery, Inha University, Incheon, Korea.

    Purposes: This study was conducted to investigate the impact of pre-transplant PRA level on rejection and graft survival after kidney transplantation in patients with negative…
  • 2015 American Transplant Congress

    Outcomes in Kidney Transplant Recipients Over Age of 55 by Donor Source: LD, SCD, ECD

    V. Kirchner, K. Gillingham, A. Matas, The Div of Tx and Tx Nephrology.

    University of Minnesota, Mpls.

    Background: Outcomes in older kidney transplant recipients from SCD and ECD have been studied; however, comparative outcomes between older recipients of LD, SCD and ECD…
  • 2015 American Transplant Congress

    Infections After Alemtuzumab Induction: A Non Issue?

    A. Smith, M. John, I. Dortonne, A. Paramesh, M. Killackey, R. Zhang, B. Lee, J. Buell.

    Transplant Institute, Tulane University, New Orleans, LA.

    Background: Alemtuzumab is a powerful induction agent that depletes multiple lymphocyte cell lines resulting in leukopenia and/or neutropenia with concerns over infectious complications. This study…
  • 2015 American Transplant Congress

    Effect of Everolimus Versus Tacrolimus On Left Ventricular Hypertrophy in Renal Transplant Patients On Maintenance

    J. Morales,1 J. Pascual,2 A. Sánchez-Fructuoso,3 D. Serón,4 J. Díaz,5 F. Oppenheimer,6 M. Rengel,7 D. Hernández,8 J. Cruzado,9 On Behalf of Evita Study Group.

    1Fund. Investigación, H. 12 Octubre, Madrid, Spain; 2S. Nefrología, H. del Mar, Barcelona, Spain; 3S. Nefrología, H. Clínico San Carlos, Madrid, Spain; 4S. Nefrología, H. Vall Hebrón, Barcelona, Spain; 5S. Nefrología, Fund. Puigvert, Barcelona, Spain; 6Unidad Trasp. Renal, H. Clínic i Provincial Barcelona, Barcelona, Spain; 7S. Urología, H. Gregorio Marañón, Madrid, Spain; 8S. Nefrología, H. Carlos Haya, Málaga, Spain; 9S. Nefrología, H. Bellvitge. IDIBELL, Barcelona, Spain.

    PURPOSE: To compare the efficacy of everolimus (EVL) in improving LVH in a regimen with mycophenolic acid (MPA) vs tacrolimus (TAC)+MPA in maintenance renal transplant…
  • 2015 American Transplant Congress

    Efficacy of Sofosbuvir Based Therapy for Recurrent Hepatitis C After Liver Transplantation

    A. Weick,1 K. George,1 S.-M. Jafri,2 D. Moonka.2

    1Internal Medicine, Henry Ford Hospital, Detroit, MI; 2Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI.

    Purpose: Evaluate outcomes of sofosbuvir-based hepatitis C therapy in liver transplant patients in a single center clinical setting, including interferon-free regimens.Methods: All patients with history…
  • 2015 American Transplant Congress

    Clinical Utility of Allospecific CD154+T-Cells in Children With Liver Or Intestine Transplantation (LTx, ITx)

    K. Soltys, G. Bond, G. Mazariegos, C. Ashokkumar, K. Dirling, L. O'Toole, P. Kachmar, T. Hartle, D. Martin, C. Trautz, R. Sindhi.

    Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.

    Background: Allospecific CD154+T-cytotoxic memory (CD154+TcM) have completed investigational evaluation as predictors of acute cellular rejection in children with LTx or ITx.Purpose: To evaluate CD154+TcM** as…
  • 2015 American Transplant Congress

    Declaring a Patient Brain Dead on Extracorporeal Membrane Oxygenation (ECMO): Are There Guidelines or Misconceptions?

    K. Kreitler,1 N. Cavarocchi,1 H. Hirose,1 S. West,2 R. Hasz,2 M. Ghobrial,3 R. Bell.3

    1Department of Surgery, Thomas Jefferson University Hospital, Philadelphia, PA; 2Gift of Life Donor Program, Philadelphia, PA; 3Department of Neurology, Thomas Jefferson University Hospital, Philadelphia, PA.

    Purpose: With the rapid growth of ECMO and the accumulating evidence that organs from ECMO donors can be safely transplanted, we reviewed the practice variations…
  • 2015 American Transplant Congress

    Primary and Secondary Vaccine Responses in a Non-Human Primate Model of Cardiac Allotransplantation

    S. Dahi,1 E. Kang,1 T. Zhang,1 B. Vanhove,2 A. Azimzadeh,1 R. Pierson III.1

    1Department of Surgery, University of Maryland School of Medicine, Baltimore, MD; 2INSERM, Nantes, France.

    Purpose: To compare the effect of calcineurin- versus costimulation-based immunosuppression on primary and secondary vaccine responses in non-human primate heart transplant recipients.Background: Antibody response following…
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