ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Avoiding Futility in Simultaneous Liver-Kidney Transplantation (SLKT): Analysis of 331 Consecutively Listed Patients

    K. Lunsford, A. Bodzin, D. Reino, A. Zarrinpar, F. Kaldas, H. Gritsch, J. Veale, G. Lipshutz, D. Farmer, G. Danovitch, H. Yersiz, J. Hiatt, R. Busuttil, V. Agopian.

    Departments of Surgery, Urology, and Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA.

    Without well-established listing guidelines for SLKT, MELD prioritization of liver recipients with renal dysfunction potentially risks scarce renal allografts. We sought to evaluate short-term predictors…
  • 2015 American Transplant Congress

    Heart Transplant for Amyloid Patients in the Current Era of Bortezomib

    J. Patel, R. Vescio, M. Kittleson, S. Siddiqui, F. Liou, J. Yabuno, L. Piponniau, B. Kearney, M. Hamilton, L. Czer, J. Kobashigawa.

    Cedars-Sinai Heart Institute, Los Angeles, CA.

    Purpose: Both amyloid light chain (AL) amyloidosis and transthyretin-related (TTR) amyloid have been viewed with reluctance to proceed with heart transplant. AL amyloid in particular…
  • 2015 American Transplant Congress

    Microvascular Inflammation in Early Protocol Biopsies of Renal Allografts in Cases of Chronic Active Antibody-Mediated Rejection

    T. Tsuji,1 M. Yanai,1 H. Itami,1 Y. Ishii,1 M. Akimoto,1 N. Fukuzawa,2 H. Harada,2 Y. Fukasawa.1

    1Demartment of Pathology, Sapporo City General Hospital, Sapporo, Japan; 2Department of Kidney Transplant Surgery, Sapporo City General Hospital, Sapporo, Japan.

    Aim:Chronic active antibody-mediated rejection (chronic ABMR) is one important cause of late-stage renal allograft loss. However, few reports have used protocol biopsy to observe changes…
  • 2015 American Transplant Congress

    Determinants and Sequelae of Hepatic Artery Thrombosis After Liver Transplantation: A Registry Study of Recipient Diagnosis and Coagulopathy

    J. Garonzik Wang,1 M. Doyle,1 K. Collins,1 J. Lowell,1 Y. Lin,1 S. Shenoy,1 J. Wellen,1 W. Chapman,1 D. Segev.2

    1Washington University, Barnes Jewish Hospital, Saint Louis, MO; 2Johns Hopkins University, Johns Hopkins Hospital, Baltimore, MD.

    Hepatic artery thrombosis (HAT) is a dreaded complication following liver transplantation. Despite improvements in technique and procurement, HAT still occurs in approximately 2-5% of recipients.…
  • 2015 American Transplant Congress

    Results of Broader Sharing of Young Pediatric Donor Lungs and Priority Allocation System for Young Pediatric Lung Candidates

    W. Cherikh,1 A. Wilk,1 L. Edwards,1 G. Visner,2 Y. Cheng,1 S. Sweet.3

    1United Network for Organ Sharing, Richmond, VA; 2Boston Children's Hospital, Boston, MA; 3Washington Univ, St. Louis, MO.

    Background. Two major changes for allocation of young pediatric (ped) lung (LU) donors and young ped candidates were implemented on 9/12/10. LUs from 0-11 year…
  • 2015 American Transplant Congress

    Iron Deficiency Impairs Regulatory T Cell Induction

    R. Danger,1 E. Bonaccorsi-Riani,1 E. Kodela,1 H. Collins,2 R. Hider,3 M. Martínez-Llordella,1 A. Sánchez-Fueyo.1

    1Department of Liver Sciences, Faculty of Life Sciences & Medicine, MRC Transplant Centre, King's College London, London, United Kingdom; 2Department of Immunology, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom; 3Institute of Pharmaceutical Science, King's College London, London, United Kingdom.

    In a recent clinical trial of immunosuppression withdrawal in adult liver transplant recipients, operational tolerance was associated with development of a transient lymphocyte infiltration rich…
  • 2015 American Transplant Congress

    Induction With ATG Is Not Associated With Increased Infections After Kidney Transplant Among HIV Positive Patients: Results of a National Study

    L. Kucirka,1 C. Durand,1 S. Bae,1 J. Locke,2 D. Segev.1

    1JHU, Baltimore; 2UAB, Birmingham.

    Anti-thymocyte globulin (ATG) is widely used for induction, particularly for those at high risk for rejection. HIV+ kidney transplant (KT) recipients have 3 fold higher…
  • 2015 American Transplant Congress

    The Use of Eculizumab to Treat the Highly Sensitized Patient Awaiting Heart Transplant

    J. Patel, D. Dilibero, M. Kittleson, S. Sana, F. Liou, D. Chang, A. Hage, L. Czer, A. Trento, N. Reinsmoen, J. Kobashigawa.

    Cedars-Sinai Heart Institute, Los Angeles, CA.

    Purpose: Highly sensitized patients (pts) awaiting heart transplantation remain a significant challenge due to prolonged often prohibitive wait times for suitable organs and increased rejection…
  • 2015 American Transplant Congress

    Kidney Double Negative TCR αβ + Cells: Newly Described Intra-Renal Kidney Lymphocytes That Respond to Ischemia Reperfusion in Mice

    M. Martina,1 S. Bandapalle,2 S. Noel,2 A. Saxena,1 A. Hamad,1 H. Rabb.2

    1Pathology, Johns Hopkins University, Baltimore, MD; 2Medicine, Johns Hopkins University, Baltimore, MD.

    Background TCRαβ+CD4-CD8- double negative (DN) T cells with immunoregulatory function are a significant component of T cells residing in the kidney. The exact role of…
  • 2015 American Transplant Congress

    Metrics of Global Health Status Signal Early Hospital Readmission Risk After Kidney Transplantation

    M. Harhay,1 A. Hill,2 W. Wang,2 O. Even-Shoshan,2 A. Mussell,1 J. Karlawish,3 R. Bloom,1 H. Feldman,1 J. Silber,2 P. Reese.1

    1Medicine, Division of Nephrology, University of Pennsylvania, Philadelphia, PA; 2Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; 3Medicine, Division of Geriatrics, University of Pennsylvania, Philadelphia, PA.

    Background: Early (≤30 days) hospital readmission (EHR) after kidney transplantation (KT) is common, with diverse causes that likely include poor pre-KT health status. Transplant providers…
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