2015 American Transplant Congress
HCV Treatment in Liver Transplantation: Changes in Center Attitudes and Practices in the DAA Era
Surgery, Johns Hopkins University, Baltimore, MD.
Chronic hepatitis C virus infection (HCV) is the leading indication for liver transplantation (LT) in the US. Safe and effective directly acting antivirals (DAAs) are…2015 American Transplant Congress
Hepatic T Cells Derived from Normothemic Machine Perfused Grafts Contained More Regulatory T Cells and Fewer Proinflammatory Cytokines Producing T Cells Than Those from Cold Storage Grafts
Background & aim:In liver transplantation, ischemia reperfusion (I/R) injury is associated with an inflammatory response affecting graft and patient outcomes. Ex-vivo normothermic machine perfusion (NMP)…2015 American Transplant Congress
Assessment of Actual Pediatric Organ Donation Potential: Neurologic and Circulatory Determination of Death at a Children's Hospital
BACKGROUND AND OBJECTIVES: Organ donation after circulatory determination of death (DCDD) is increasing. DCDD offers potential for additional abdominal organ donation. We evaluated all dying…2015 American Transplant Congress
Attitudes and Beliefs About Organ Donation: Focus Group Study in Arabic-Speaking Communities in Australia
Background: The demand for transplantable organs continues to outweigh supply across the globe, especially in the provision of deceased donor organs from ethnic minority populations.…2015 American Transplant Congress
Human Adipose Derived Mesenchymal Stem Cells Enhance Bone Marrow Engraftment and Induce Immunological Tolerance
1UMASS, Worcester; 2Alpert Medical School of Brown University, Providence.
Organ transplantation currently requires long-term immunosuppression. This is associated with multiple complications including infection, malignancy and other toxicities. Immunologic tolerance is considered the optimal solution…2015 American Transplant Congress
Relative In Vitro Immunoregulatory Effects of Everolimus, Sirolimus, Tacrolimus, Mycophenolic Acid and Drug Combinations
Everolimus (EVL) is a modified form of the mTOR-inhibitor Sirolimus (SRL) and is used clinically in combination with Mycophenolate (MMF) and/or Tacrolimus (TAC). The purpose…2015 American Transplant Congress
Chimerism for Early Detection of Graft Versus Host Disease in Intestinal Transplantation
Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, FL.
Graft versus host disease (GVHD) is a potentially fatal complication after multivisceral transplantation (MVT). By definition, donor cells must be present in the blood of…2015 American Transplant Congress
Acute Kidney Injury and Outcome After Cardiac Transplantation
Background:Chronic kidney disease (CKD) is a frequently seen complication after cardiac transplantation and is partly explained by the prolonged use of calcineurin inhibitors. However, few…2015 American Transplant Congress
Epidemiology and Outcomes of Pre-Transplant Methicillin Resistant Staphylococcus Aureus Screening in Pediatric Solid Organ Transplant Candidates
Purpose: Infection following pediatric solid organ transplantation (SOT) is a major cause of morbidity and mortality. Peri-operative antibiotic prophylaxis is commonly used to reduce the…2015 American Transplant Congress
Hypothermic Machine Perfusion Improves the Quality of Marginal Donor Pancreata
Introduction. Pancreas or islet transplantation is considered the most effective treatment for patients with type 1 diabetes mellitus. Due to the persistent organ shortage, pancreata…
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