ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Stem Cell and Novel Biologic Therapies to Enhance Functional Recovery in Limb Transplantation

    K. Kniery, M. DeHart, T. Brown, S. Salgar.

    Surgery/Clinical Investigation, Madigan Army Medical Center, Tacoma, WA.

    Introduction: Unlike visceral organ transplants, vascular composite allotransplantation such as limb and face require successful nerve regeneration and reinnervation of graft motor and sensory targets…
  • 2015 American Transplant Congress

    Surgical Error: A Common, Preventable Threat to Deceased Donor Organs

    A. Friedman,1 T. Diflo,2 S. Florman,3 L. Ratner,4 E. Marquez,1 W. Tajik.1

    1New York Organ Donor Network, New York, NY; 2Westchester Medical Center, Valhalla, NY; 3Mount Sinai School of Medicine, New York, NY; 4Columbia Presbyterian Medical Center, New York, NY.

    Deceased donor procurements (N = 340) performed through a single organ procurement organization during a 19 month period from 7/1/13 - 11/30/14 were reviewed through…
  • 2015 American Transplant Congress

    Histology and Not Donor Specific Antibody Helps Predict 5-Year Kidney Transplant Failure Using 1 Year Post-Transplant Data

    M. Moreno Gonzales,1 A. Bentall,2,3 M. Stegall,1 R. Borrows.2

    1Department of Transplant Surgery, Mayo Clinic, Rochester, MN; 2Department of Nephrology, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom; 3School of Immunity and Infection, University of Birmingham, Birmingham, United Kingdom.

    Introduction: The objective of this study was to validate the RISK score (Am J Kid D 2014; 63[4]:643) for renal allograft failure using a different…
  • 2015 American Transplant Congress

    Is Transplant Volume Associated With Survival in Pediatric Liver Transplants?

    W. Cherikh,1 H. Kim,2 A. Wilk,1 C. Flavin,1 E. Brewer.3

    1United Network for Organ Sharing, Richmond, VA; 2Boston Children's Hospital, Boston, MA; 3Baylor Coll Med & Texas Children's Hosp, Houston, TX.

    Background. Center specific volume has been shown to correlate with outcomes for many procedures in the adult population. The current study was conducted to determine…
  • 2015 American Transplant Congress

    No Significant Outcome Benefit for Brand-Name Versus Generic Tacrolimus in Kidney Transplant Recipients: SRTR Analysis

    D. Goldfarb,1 E. Poggio,1 S. Flechner,1 R. Fatica,1 J. Schold.2

    1Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH; 2Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.

    IntroGeneric formulations of tacrolimus have been available for maintenance immunosuppression since 2009. Our aim was to evaluate the frequency of use of generic tacrolimus and…
  • 2015 American Transplant Congress

    Rise in Deceased Donors Labeled "Increased Risk for Disease Transmission" Under New Guidelines

    L. Kucirka, M. Bowring, A. Massie, L. Nicholas, X. Luo, D. Segev.

    JHU, Baltimore.

    Deceased donors are labeled increased infectious risk (IRD) if they meet certain criteria; however, stigma, legal and regulatory burden to centers, and decreased organ utilization…
  • 2015 American Transplant Congress

    APOL1 High-Risk Genotype in African American Live Kidney Donors Is Not Associated With Post-Donation Development of Hypertension and Kidney Disease

    M. Doshi,1 M. Goggines,2 C. Winkler,3 J. Kopp.4

    1Wayne State University, Detroit, MI; 2Henry Ford Transplant Institute, Detroit, MI; 3NCI and Leidos, Frederick, MD; 4NIDDK, Bethseda, MD.

    African Americans (AA) with two apolipoprotein L1 (APOL1) risk alleles have more kidney disease than compared to those with one or zero risk alleles. A…
  • 2015 American Transplant Congress

    Notch Signaling Mediates Epithelial-to-Mesenchymal Transition in the Development of Marginal Liver Graft Fibrosis

    X. Liu, K. Man, K. Ng, C. Lo.

    Depatment of Surgery, The University of Hong Kong, Hong Kong, China.

    Background and aims:Although graft size and chronic liver diseases have been proposed as risk factors for post-transplantation liver fibrosis, the underlying mechanisms remained unclear. Our…
  • 2015 American Transplant Congress

    Steroid Free Immunosuppression Protocol in Pediatric Kidney Transplant Recipients Using Alemtuzumab: A Retrospective Single Center Study

    R. Shah,1 Z. Kadry,1 S. Wassner,2 D. Kees-Folts,2 M. Freeman,2 P. Freeman,1 B. Olenowski,1 A. Jain.1

    1Surgery, Hershey Medical Center, Hershey, PA; 2Pediatric Nephrology, Hershey Medical Center, Hershey, PA.

    Background: Steroid free immunosuppression is attractive in pediatric kidney transplantation (KTx). Aim of the present study is to examine the patient survival, graft survival, rate…
  • 2015 American Transplant Congress

    Allograft Class II MHC and CD40 Expression Are Required for Endogenous Memory CD8 T Cell Proliferation in Cardiac Allografts Subjected to Prolonged Cold Ischemic Storage

    T. Tanaka,1,2 H. Tsuda,1,3 N. Kohei,1,4 D. Kish,1 W. Baldwin,1 A. Valujskikh,1 R. Fairchild.1

    1Immunology, Cleveland Clinic, Cleveland, OH; 2Urology, Sapporo Medical University, Sapporo, Japan; 3Urology, Osaka University, Osaka, Japan; 4Urology, Kidney Center, Tokyo Women's Medical University, Tokyo, Japan.

    Endogenous memory CD8 T cells infiltrate MHC-mismatched cardiac allografts and produce IFN-γ in response to donor class І MHC within 24 hrs after graft reperfusion…
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