ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Losartan Benefits Are Mediated Through SIRT1 Activation in Rat Reduced Size Orthotopic Liver Transplantation

    E. Pantazi,1 M. Bejaoui,1 M. Zaouali,1 E. Folch-Puy,1 A. Rolo,2,3 A. Panisello,1 C. Palmeira,2 J. Rosello-Catafau.1

    1Experimental Pathology, Institute of Biomedical Research of Barcelona (IIBB-CSIC), Barcelona, Spain; 2Department of Life Sciences, Faculty of Science and Technology, University of Coimbra, Coimbra, Portugal; 3Center for Neurosciences and Cell Biology, Department of Zoology, University of Coimbra, Coimbra, Portugal.

    Background: Silent Information Regulator 1 (SIRT1) is a histone deacetylase that has been associated with protective mechanisms against IRI, but its role in liver transplantation…
  • 2015 American Transplant Congress

    Prediction of Delayed Graft Function By Means of a Web-Based Calculator in Living Related Kidney Transplant: Mexican Single Center Experience

    G. Martinez-Mier,1 E. Soto-Miranda,1 M. Mendez Lopez,1 L. Budar Fernandez,1 M. Trujillo-Martinez,2 A. Uscanga-Montesano,2 D. Avila y Falfan.2

    1Organ Transplantation, IMSS UMAE189/HRAEV Nefrologia y Trasplantes de Veracruz, Veracruz, Mexico; 2Research, IMSS UMAE 189, Veracruz, Mexico.

    Background: Delayed graft function (DGF) is associated with, poor graft survival. Irish validated a model to predict DGF for deceased donor transplants. The model was…
  • 2015 American Transplant Congress

    Change in Health-Related Quality of Life Between Evaluation for Kidney Transplantation and Transplantation

    M. McAdams-DeMarco, E. King, N. Desai, N. Dagher, B. Lonze, R. Montgomery, D. Segev.

    Johns Hopkins, Baltimore.

    BACKGROUND: Kidney transplantation (KT) recipients have been found to have higher Health-related quality of life (HRQOL) than patients undergoing other forms of renal replacement therapy.…
  • 2015 American Transplant Congress

    Predictors of Deceased Donor Lung Utilization in the United States

    L. Edwards,1 L. Robbins Callahan,1 J. Rogers,2 K. Chan.3

    1United Network for Organ Sharing, Richmond, VA; 2Duke University Medical Center, Durham, NC; 3University of Michigan Health System, Ann Arbor, MI.

    Background: Lung utilization rates for deceased donor (DD) are far lower than most solid organs. For DD recovered in 2013, 22% had at least one…
  • 2015 American Transplant Congress

    Similar Outcomes Can Be Expected Among HIV (+) Kidney Transplant Recipients (HIV+ Tx) Vs. HIV (-) Kidney Transplant Recipients (HIV- Tx) Receiving Similar Immunosuppression Protocols

    L. Panarey,1 G. Malat,2,3 A. Sharma,1 K. Ranganna,1 D. Reich,2 G. Xiao,2 A. Doyle.1

    1Dept of Medicine, Drexel University College of Medicine, Philadelphia; 2Dept of Surgery, Drexel University College of Medicine, Philadelphia; 3Dept of Pharmacy, Hahnemann University Hospital, Philadelphia, PA.

    Outcomes among HIV+ Tx continue to improve despite the established risk of rejection and calcineurin-nephrotoxicity. We sought to compare outcomes among HIV+ Tx vs. HIV-…
  • 2015 American Transplant Congress

    Donor Selection and Prophylactic IVIg for Induction Immunosuppression Improves Outcomes for HIV+ Kidney Transplant Recipients (HIV+ Tx)

    G. Malat,1,2 L. Panarey,3 A. Sharma,3 K. Ranganna,3 D. Reich,2 G. Xiao,2 A. Doyle.3

    1Dept of Pharmacy, Hahnemann University Hospital, Philadelphia; 2Dept of Surgery, Drexel University College of Medicine, Philadelphia; 3Dept of Medicine, Drexel University College of Medicine, Philadelphia, PA.

    HIV+ Tx recipients are noted to have higher rates of allorecognition through cellular and humoral mediated pathways. Since 2010, our program instituted IVIg use as…
  • 2015 American Transplant Congress

    NK-Cell Subset Distribution, Renal Function and Biopsy Findings in Kidney Transplant Recipients With HLA Donor-Specific Antibodies

    M. Crespo,1 D. Redondo,1 J. Gimeno,2 J. Yelamos,3 A. Muntasell,3 A. Faura,1 M. Pérez-Sáez,1 M. López-Montañes,4 A. Torío,5 C. García,6 M. Mir,1 J. Hernandez,6 M. López-Botet,3,4 J. Pascual.1

    1Nephrology Unit, Hospital del Mar, Barcelona, Spain; 2Servicio de Anatomía Patológica, Hospital del Mar, Barcelona, Spain; 3Servicio de Inmunología, Institut Mar d'Investigacions Mediques, Barcelona, Spain; 4Universitat Pompeu Fabra, Barcelona, Spain; 5Laboratori de Referencia de Catalunya, Barcelona, Spain; 6Immunology Department, Hospital de Alicante, Alicante, Spain.

    Background: Detection of post-transplant donor-specific anti-HLA antibodies(DSA) constitutes a risk factor for kidney transplant (KT) loss. NK-cell antibody-dependent cell mediated cytotoxicity(ADCC) has been proposed to…
  • 2015 American Transplant Congress

    Cyclophosphamide as a Salvage Therapy for Combined Intravenous Immunoglobulins and Plasmapheresis Refractory Antibody-Mediated Rejection

    W. Habhab,1 A. Dada,2 M. Alwassia,1 N. Baz,2 N. Zabani,1 A. Fahmy,1 A. Abdul Malik.1

    1Nephrology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia; 2Pathlogy, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.

    Acute antibody-mediated rejection (AMR) poses a significant risk to graft survival. Current or standard treatment (ST) of AMR currently consists of plasmapheresis (PP), intravenous immunoglobulin…
  • 2015 American Transplant Congress

    Kidney Patients at High Immunological Risk Can Be Safely Transplanted With a Novel Induction Regimen Using Anti-Thymocyte Globulin (Rabbit) (rATG) Plus Basiliximab

    D. Halleran,1 J. Melancon,2 V. Whittaker.1

    1Surgery, State University New York Upstate Medical University, Syracuse, NY; 2Surgery, George Washington University, Washington, DC.

    Purpose: We report the outcomes from our single center experience with the novel induction regimen using rATG (3 mg/kg) in divided doses given on operative…
  • 2015 American Transplant Congress

    Effect of Induction in Renal Transplant Recipients Aged 70 and Over

    M. Lubetzky, M. Ajaimy, L. Kamal, G. DeBoccardo, E. Akalin.

    Transplantation, Montefiore Medical Center, Bronx, NY.

    While there is a significant survival advantage to transplanting patients 70 years of age and older versus staying on dialysis, it is unclear whether sensitized…
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