Am J Transplant, Volume 5, Suppl 3 Archives - Page 101 of 170 - ATC Abstracts

2015 American Transplant Congress
Clinical Consequences of Immune-Mediated Allograft Arteriosclerosis: A Population Based Study
A. Loupy, Vernerey, Viglietti, Aubert, Duong van Huyen, Bruneval, Empana, Suberbielle, Glotz, Jouven, Legendre, Lefaucheur.
Paris Translational Research Center for organ Transplantation, Paris, France.
BACKGROUNDThe role of circulating antibodies and alloimmune response beyond traditional cardiovascular risk factors in the development of accelerated arteriosclerosis and its long-term clinical consequences is…
2015 American Transplant Congress
Serial Changes in Body Composition After Kidney Transplantation
S. Deger,¹ A. Bian,² G. Chen,² T. Ikizler,¹ K. Birdwell.¹
¹Medicine, Vanderbilt University Medical Center, Nashville, TN; ²Biostatistics, Vanderbilt University Medical Center, Nashville, TN.
BACKGROUND: A significant long-term nutritional problem after kidney transplantation is obesity. We examined the changes in body composition after transplantation and its determinants.METHODS: A total…
2015 American Transplant Congress
End of Treatment Liver Biopsy With Sofosbuvir: Histologic Changes Suggestive of Hepatitis C Activity in Liver Transplant Recipients With Achieved SVR
B. Ismail,¹ X. Zervos,¹ P. Bejarano,² M. Waton,¹ D. Beltran,³ D. Sears,¹ A. Tzakis.¹
¹Liver Transplant, Cleveland Clinic Florida, Weston, FL; ²Pathology, Cleveland Clinic Florida, Weston, FL; ³Pharmacy, Cleveland Clinic Florida, Weston, FL.
Background: Interferon (IFN) free HCV regimens are associated with better tolerability and efficacy. The majority of studies report biochemical and virological response; however limited information…
2015 American Transplant Congress
Does Smoking Lead to Increased Rates of Acute Cellular Rejection in Liver Transplant Recipients?
B. Rao,¹ D. Montezuma-Calvo,² K. Tosch,² S.-M. Jafri.²
¹Internal Medicine, Henry Ford Hospital, Detroit, MI; ²Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI.
Introduction: Prior studies of liver transplant recipients who smoke have shown associations between mortality and adverse outcomes. We investigated if smoking status at the time…
2015 American Transplant Congress
Trends in Transplant Patient Safety Situation Reporting
T. Daly,¹ H. Neil,² D. Stewart,² S. Tlusty,² A. Harper,² D. Marshman,³ M. Green.⁴
¹NY-Presbyterian Hosp., New York, NY; ²UNOS, Richmond, VA; ³LifeNet Health, Roanoke, VA; ⁴Children's Hosp. of Pittsburgh, Pittsburgh, PA.
Background: The OPTN Operations & Safety Committee is charged with reviewing aggregated, de-identified safety situation data reported through both the UNet Improving Patient Safety (IPS)…
2015 American Transplant Congress
DNA Methytransferase 1 Inhibition Potently Suppresses T Cell Cycle Progression Through Demethylation of the Key Cell Cycle Inhibitors p15, p16, p21 and p27
T. Ma, Y. Pei, R. Tao.
Department of Hepatobiliary-Pancreatic Surgery, Zhejiang Provincial Peoples' Hospital, Hangzhou, Zhejiang Province, China.
Background: Epigenetic mechanisms like acetylation and methylation have been gradually appreciated to play a critical role in the generation and function of various immune cells.…
2015 American Transplant Congress
A Novel Post-Transplant High-Dose Cyclophosphamide-Based Regimen to Promote Immune Tolerance After VCA
G. Furtmüller,¹ M. Fryer,¹ B. Oh,¹ S. Ganguly,² J. Izzi,³ D. Cooney,¹ G. Raimondi,¹ W. Lee,¹ L. Luznik,² G. Brandacher.¹
¹Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD; ²Immunology - Sydney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD; ³Department of Research Animal Resources, Johns Hopkins University, Baltimore, MD.
Background: VCA has become a viable treatment option for devastating tissue defects. However, the life-long need of immunosuppressive medications curtails the wider use of VCA.…
2015 American Transplant Congress
Tacrolimus Trough Concentrations Increase in Intestinal Transplant Recipients During Episodes of Acute Cellular Rejection
A. Lichvar,¹ D. Deen,² H. Johnson,¹ J. Bonner,³ G. Bond,⁴ G. Costa,⁴ R. Cruz,⁴ K. Abu-Elmagd,⁵ R. Venkataramanan.^6,7
¹Department of Pharmacy and Therapeutics, University of Pittsburgh Medical Center, Pittsburgh, PA; ²Department of Pharmacy, Memorial University Medical Center, Savannah, GA; ³Northern Institute for Cancer Research at Newcastle University, Tyne and Wear, United Kingdom; ⁴Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA; ⁵Center for Gut Rehabilitation and Transplantation, Cleveland Clinic, Cleveland, OH; ⁶Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA; ⁷Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Introduction: Acute cellular rejection (ACR) in small bowel transplant recipients is expected to increase intestinal permeability and to reduce intestinal CYP3A/p-glycoprotein activity. These changes may…
2015 American Transplant Congress
Responsiveness to Rituximab, Plasmapheresis and Intravenous Immunoglobulins in Antibody Mediated Rejections After Kidney and Pancreas – Kidney Transplantation
E. Minué,¹ L. León,¹ P. Uva,¹ A. Dotta,¹ J. Walther,¹ O. Casanova,¹ F. Togniolo,¹ O. Guardia,¹ M. Rial,¹ E. Chuluyan,² D. Casadei.¹
¹Instituto de Nefrologia, Nephrology, Buenos Aires, Argentina; ²CEFYBO, Universidad de Buenos Aires-CONICET, Buenos Aires, Argentina.
The antibody-mediated rejection (AMR) has become clinically critical because this form of rejection is usually unresponsive to conventional anti-rejection therapy. Therefore, it has been recognized…
2015 American Transplant Congress
Social Support After Heart Transplant
E. Stimpson, T. Kao, L. Kim, S. Morrison, J. Patel, M. Kittleson, F. Liou, S. Siddiqui, J. Yabuno, L. Czer, J. Kobashigawa.
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: Social support of patients awaiting heart transplant is mandatory to secure acceptable outcomes after heart transplantation. The types of social support that we have…