2015 American Transplant Congress
Epigenetic Reprogramming of Murine Cytomegalovirus Immediate Early Genes Induced By Renal Transplantation
Background: Reactivation of latent CMV is a significant infectious complication in solid organ transplant recipients. MCMV is a valuable model for studying molecular mechanisms controlling…2015 American Transplant Congress
Correlates of Clinical Course of Polyomavirus BK Infection With Long-Term Outcome of BK Virus-Associated Nephropathy in Renal Transplant Patients
Background: Identification of risk factors for the long-term outcome of BK virus (BKV) -associated nephropathy(BKVAN) may improve renal transplant outcome. Methods: Between 2006 and 2014,…2015 American Transplant Congress
Histologic Findings in Pre-transplant AT1Rab + ve Patients Point to an Increase in Sub-Intimal Fibrosis During Acute Rejection and in 12 mo. Protocol Renal Graft Biopsies
Previous reports have described an increase in arteritis during acute rejection (AR) in angiotensin II type 1 receptor antibody (AT1Rab) positive (ve+) kidney transplant recipients…2015 American Transplant Congress
Post-Transplant Recurrence of Calcium Oxalate Crystals in Primary Hyperoxaluria Type 1 Detected by Surveillance Biopsies: Incidence, Risk Factors, and Effect on Graft Function
Background: Primary hyperoxaluria type 1 (PH1) is a rare metabolic defect that results in oxalate over-production by the liver and leads to renal disease due…2015 American Transplant Congress
Pediatric Living Donor Liver Transplantation at KFSH&RC – Implementation of the Laparoscopic Retrieval in a High Volume Center
Organ Transplant Centre, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.
Since the first successful pediatric liver transplantation was performed in 1967 the survival rate increased from 30 % to currently above 90 %. This is…2015 American Transplant Congress
Isolated Microcirculation Inflammation Negatively Impacts Renal Graft Function at 5 Years
BACKGROUND: Microcirculation inflammation (MI, ie: glomerulitis (g) and peritubular capillaritis (ptc)) associated with anti-HLA Donor Specific Antibody (DSA) with or without C4d deposits in ptc…2015 American Transplant Congress
Correlation Between C3d-Binding De Novo Donor Specific HLA Antibodies and Rejection in Kidney Transplant Recipients
Comprehensive Transplant Center, Northwestern University, Chicago, IL.
Donor specific antibodies (DSA) directed against HLA arising de novo post-kidney transplant are a major cause of graft loss, termed antibody mediated rejection (AMR). Currently,…2015 American Transplant Congress
Preformed Anti-HLA DP Donor Specific Antibodies Are Clinically Significant in Renal Transplantation
Renal and Transplant Medicine, Imperial Healthcare NHS Trust, London, United Kingdom.
Background: Whilst preformed [PF] anti-HLA A, B, DR and DQ donor specific antibodies [DSAbs] are associated with poorer allograft outcomes secondary to antibody mediated injury,…2015 American Transplant Congress
Octogenarian Kidney Transplant Recipients: A Single Center Experience
University of Maryland Medical Center, Baltimore, MD.
Background: Elderly patients are the fastest growing population requiring kidney transplantation internationally. Previous studies have shown a survival benefit for kidney transplantation when compared to…2015 American Transplant Congress
Induction With an Interleukin-2 Receptor Antagonist in Sensitized Adult Kidney Transplant Recipients Is Highly Effective and Safe
Background: The effectiveness and safety of induction with basiliximab (IL2RA) in sensitized kidney transplant recipients is not clearly established. The aim of this study was…
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