ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Do Community-Solicited NDDs Experience More Coercion to Donate a Kidney Than Traditional NDD Donors?

    D. Serur, G. Bretzlaff, P. Christos, F. Desrosiers, M. Charlton.

    New York Presbyterian Weill Cornell, New York, NY.

    BACKGROUND:Studies of non-directed donors (NDDs) have shown comparable psychosocial functioning to traditional donors. Within NDDs there are some that come forward in response to community…
  • 2015 American Transplant Congress

    Donor Obesity Impact on Simultaneous Kidney-Pancreas Transplantation Outcomes

    T. Alhamad,1 A. Malone,1 H. Chakkera.2

    1Transplantation Nephrology, Renal Division, Washington University, St Louis; 2Renal Division, Mayo Clinic, Phoenix, AZ.

    Background: Donor obesity has been reported as a risk factor for early pancreas allograft failure. The relationship between donor obesity and long-term pancreas allograft survival…
  • 2015 American Transplant Congress

    Import Pancreas Transplants: Good from Far or Far from Good?

    J. Rogers, A. Farney, G. Orlando, A. Reeves-Daniel, A. Palanisamy, H. El-Hennawy, M. Khan, M. Gautreaux, S. Iskandar, R. Stratta.

    General Surgery-Transplantation, Wake Forest Baptist Medical Center, Winston-Salem, NC.

    Background: Many transplant (tx) programs are reluctant to import pancreas allografts because of concerns that outcomes might be inferior to locally procured organs. Methods: Single…
  • 2015 American Transplant Congress

    A Discrete Choice Experiment to Explore Patients' Preferences for Kidney Transplant Monitoring by Video-Conferencing

    S. Brunet-Houdard,1 M. Giral,2 S. Gaboriau,2 A. Meurette,2 P. Daguin,2 P. Tessier.3

    1UEME, SIMEES, Tours University Hospital, Tours, France; 2Nantes University Hospital, Nantes, France; 3EA 4275, Nantes University, Nantes, France.

    INTRODUCTIONAn experiment to assess the clinical outcomes and the economic efficiency of a videoconferencing system for the renal transplant patient's monitoring is currently under way…
  • 2015 American Transplant Congress

    Does Transversus Abdominis Plane Block Reduce Opioid Analgesic Requirements in the Post-Operative Period in Renal Transplant Recipients?

    F. Afridi,1 R. Coates,1 S. Wright,2 J. French,1 D. Talbot,1 S. Rita.2

    1Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, Tyne and Wear, United Kingdom; 2Department of Anesthesia, Freeman Hospital, Newcastle upon Tyne, Tyne and Wear, United Kingdom.

    Introduction: Renal transplant recipients are a challenge where pain management is concerned. The theory that transversus abdominis plane (TAP) block provides additional analgesic benefit reducing…
  • 2015 American Transplant Congress

    Identification of miRNAs Associated With Induced Tolerance to Allografts

    M. Vitalone, L. Wei, C. Esquivel, S. Busque, O. Martinez, S. Krams.

    Surgery-Transplantation, Stanford University School of Medicine, Stanford, CA.

    Introduction: Although the liver is less immunogenic than other solid organs, most liver transplant recipients receive lifelong immunosuppression. Total lymphoid irradiation (TLI) is part of…
  • 2015 American Transplant Congress

    Phenotypic Personalized Medicine: Mechanism-Independent Convergence Into Target Serum Tacrolimus Levels for Optimized Liver Transplant Immunosuppression

    A. Zarrinpar,1 A. Silva,2 D.-K. Lee,3 N. Datta,1 C.-M. Ho,2 D. Ho.3

    1Surgery-Division of Liver and Pancreas Transplantation, UCLA, Los Angeles, CA; 2Mechanical Engineering, UCLA, Los Angeles, CA; 3Bioengineering, and Oral Biology and Medicine, UCLA, Los Angeles, CA.

    PURPOSE:Immunosuppressive drugs such as tacrolimus have narrow therapeutic ranges and their dosing variability necessitates intensive drug monitoring. This study aimed to use Feedback System Control…
  • 2015 American Transplant Congress

    Pre-Transplant Levels of TFH cell-Inducing Pro-Inflammatory Cytokines Correlate With DSA Formation After Kidney Transplantation

    C. Macedo,1 K. Hadi,1 B. Elinoff,1 M. Marrari,1 A. Zeevi,1 B. Ramaswami,1 G. Chalasani,1 A. Shields,2 R. Alloway,3 E. Woodle,2 F. Lakkis,1 D. Metes.1

    1Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh; 2Surgery, University of Cincinnati College of Medicine, Cincinnati; 3Internal Medicine-Nephrology, University of Cincinnati College of Medicine, Cincinnati.

    Donor-specific anti-HLA antibodies (DSA) represent an important biomarker for acute rejection and are a major cause of long-term graft failure after kidney transplantation (KTx). The…
  • 2015 American Transplant Congress

    Characterization of Natural T Effector Memory Cells Specific for Collagen type V, k-α-1-Tubulin and Vimentin

    J. Sullivan,1 D. Wilkes,2 T. Mohanakumar,3 W. Burlingham.1

    1Surgery, University of Wisconsin, Madison, WI; 2Medicine, Indiana University, Indianapolis, IN; 3Surgery, Washington University, St. Louis, MO.

    Background: Injury and repair processes are highly controlled, common occurrences of healthy tissue remodeling. During this process, cellular antigens that are not normally exposed to…
  • 2015 American Transplant Congress

    CD28 Saturation by FR104, a Non-Activating CD28 Antagonist Fab in a Non-Human Primate Cardiac Allograft Model

    W. Sun,1 A. Azimzadeh,1 G. Braileanu,1 T. Zhang,1 D. Amoako,1 L. Burdorf,1 B. Vanhove,2 R. Pierson III.

    1Dept of Surgery, University of Maryland School of Medicine, Baltimore, MD; 2INSERM U643, Nantes, France.

    Background: Targeting CD28 costimulation pathway with a selective antagonist is a promising approach in tolerance induction. The extent to which novel therapeutic antibodies reach their…
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