ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Day of Week Influences Kidney Utilization

    K. Foley, M. Chiles, S. Mohan.

    Department of Medicine, Columbia University Medical Center, New York, NY.

    Background: From 2000 to 2013, 17% of all kidneys procured for transplantation from deceased organ donors in the United States were discarded. The high rate…
  • 2015 American Transplant Congress

    Emerging Application of Active Immune Targeted Delivery in Transplantation

    M. Uehara,1 A. Jamil,1 M. McGrath,1 Z. Solhjou,1 N. Banouni,1 S. Tullius,2 C. Jianjun,3 R. Abdi.1

    1Renal Division, Transplantation Research Center, Brigham and Women's Hospital, Harvard Medical Shcool, Boston, MA; 2Division of Transplant Surgery, Brigham and Women's Hospital, Boston, MA; 3Materials Science and Engineering, University of Illinois at Urbana-Champaign, Champaingn, IL.

    Targeted nanodelivery has created enormous excitement as a transformative approach to deliver therapeutics to tissues of interest. In recent years, we have made significant progress…
  • 2015 American Transplant Congress

    IL-33 Enhances Host Tolerance to Candida albicans Kidney Infections Through Induction of IL-13 Production by CD4+ T Cells

    H. Cho,1,2 J. Lee,2,3 V. Tran,4 H. Kim,2,4 J. Kim,2,4 B. Kwon.2,4

    1Surgery, Ulsan University Hospital, Ulsan, Korea; 2Biomedical Research Center, Ulsan University Hospital, Ulsan, Korea; 3Internal Medicine, Ulsan University Hospital, Ulsan, Korea; 4School of Biological Sciences, University of Ulsan, Ulsan, Korea.

    Susceptibility to systemic Candida albicans infection is determined not only by immune resistance but also by the ability to control Candida-induced immunopathologies. We previously showed…
  • 2015 American Transplant Congress

    Allograft Enterectomy as a Life-Saving Procedure and Salvage for Retransplantation

    S. Nagai, R. Mangus, B. Ekser, C. Kubal, J. Fridell, A. Tector.

    Transplant Surgery, Indiana University School of Medicine, Indianapolis, IN.

    Background: Allgraftectomy after solid organ transplantation is usually performed as a palliative therapy. After isolated intestinal transplantation (IIT), allograft enterectomy is sometimes necessary as a…
  • 2015 American Transplant Congress

    DSA Monitoring in Kidney Transplant Recipients

    F. Pean,1 M. Cooper,1 J. Verbesey,1 A. Gilbert,1 B. Javaid,1 R. Mohammed,1 O. Timofeeva,2 J. Moore,1 K. Cruz,1 R. Ghasemian,1 T. Fishbein,1 M. Grafals.1

    1Medstar Georgetown Transplant Institute, Georgetown University, Washington, DC; 2Clinical Laboratory and Histocompatibility, Georgetown University, Washington, DC.

    Introduction: The development of DSA monitoring is a new technique to detect antibodies in kidney transplant recipients. Data has shown that development of DSA post…
  • 2015 American Transplant Congress

    Increased Length of Stay After Heart Transplant: What Are the Risk Factors?

    A. Velleca, M. Kittleson, N. Perry, J. Patel, F. Liou, S. Siddiqui, J. Rush, D. Ramzy, L. Czer, D. Chang, J. Kobashigawa.

    Cedars-Sinai Heart Institute, Los Angeles, CA.

    Purpose: Initial hospital length of stay following heart transplant is variable. The longer the hospital stay, the increased cost related to the surgery. This will…
  • 2015 American Transplant Congress

    Outcome of Invasive Aspergillosis in Liver Transplant Recipients Under Current Antifungal Therapy

    U. Herden, E. Grabhorn, B. Nashan, L. Fischer.

    University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

    Introduction: Invasive aspergillosis is a rare but severe complication following liver transplantation (LTX) with reported mortality rates up to 100%. Our purpose was to investigate…
  • 2015 American Transplant Congress

    Orthotopic Transplantation of a Tissue Engineered Skin Graft in Athymic Mice

    N. Nayakawde, P. Patil, K. Methe, M. Olausson.

    Surgery, Gothenburg University, Gothenburg, Vastra Gotaland, Sweden.

    Background: Tissue engineered (TE) skin offers promising alternative treatment in wound healing of acute and chronic skin injuries. Limited autografts from donor skin and risks…
  • 2015 American Transplant Congress

    Establishment of Diabetes Modeling in Common Marmoset

    W. Yuan,1 S. Fukuda,1 T. Inoue,2 D. Chujo,1 H. Okochi,1 E. Sasaki,2 M. Shimoda.1

    1National Center for Global Health and Medicine, Tokyo, Japan; 2Central Institute for Experimental Animals, Kawasaki, Japan.

    Background:Diabetic nonhuman primates (NHPs) are considered as the good models for both diabetes mellitus research and islet transplantation research safely into clinical applications. However, there…
  • 2015 American Transplant Congress

    Ischemia-Induced Endoplasmic Reticulum Stress Regulates Autophagy to Determine the Severity of Liver Ischemia Reperfusion Injury

    H. Zhou,1,2 J. Zhu,1 S. Yue,1 R. Busuttil,1 J. Kupiec-Weglinski,1 Y. Zhai.1

    1The Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA; 2Liver Transplant Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.

    Both endoplasmic reticulum (ER) stress and autophagy have been implicated in the pathogenesis of ischemia and reperfusion injury (IRI). As essential cellular stress responses against…
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