2013 American Transplant Congress
Generation of HLA-Specific Humanised Mice Using Bone Marrow-Derived Haematopoietic Stem Cells from Cadaveric Organ Donors
Department of Surgery, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom
Introduction‘Humanised’ mice reconstituted with a functional immune compartment are an invaluable tool in the study of the immune response and can be generated using haematopoietic…2013 American Transplant Congress
Improving Pancreatic Islet Engraftment through Manipulation of Their Size
Although islet isolation techniques have been improved overtime, protocols and products are not completely standardized. It is known that following transplantation (Tx) from 30 to…2013 American Transplant Congress
CD39 Regulates the Activation of Liver DC and Protects Against Liver Transplant Ischemic Reperfusion Injury
Background: ATP is an energy source stored in the cell cytosol. Once released into extracellular(e) space as a result of cell injury/death, eATP acts in…2013 American Transplant Congress
Effects of Viral Infection on Chronic Anti-Mediated Rejection, The
Emory Transplant Center, Atlanta
[Background] Despite a 50% decline in acute rejection over the past 10 years, antibody-mediated injury has been identified as perhaps the leading cause of chronic…2013 American Transplant Congress
Does Secondary Prophylaxis Prevent CMV Relapse Following Treatment of CMV Disease in Kidney Transplant Recipients?
Division of Infectious Diseases, Mount Sinai Hospital, New York, NY
BackgroundAlthough many centers use secondary prophylaxis to prevent relapse following the treatment of CMV disease in kidney transplant recipients (KTR), there is limited data to…2013 American Transplant Congress
Novel Model of Antibody Mediated Rejection of Kidney Allografts in Rats, A
We have developed a new experimental model of acute ABMR, in which complete MHC mismatched kidneys are transplanted from Brown Norway rats (RT1n) into Lewis…2013 American Transplant Congress
Donor Comorbidities Rather Than Age Alone Determine Recipient Outcomes in "SCD" Kidney Transplants
The Transplant Institute, Henry Ford Hospital, Detroit, MI
Deceased donor (DD) pool has been expanded with kidneys that have wide-ranging functional vitality and pathologic features stemming from increasing incidence of metabolic syndrome. To…2013 American Transplant Congress
Non-Renal Solid Organ Transplant (NRSOT): The Role of the Transplant Nephrologist before Advanced Stage Chronic Kidney Disease (CKD)
Background: Many patients who have not undergone appropriate kidney evaluation pre-NRSOT are found to have progressive or end-stage renal disease post-NRSOT. Recipients of NRSOT who…2013 American Transplant Congress
Parent and Child Perceptions of Long Term Psychosocial Functioning at > 5 Years Post-Intestine Transplant (ITx)
With improved survival following pediatric ITx, evaluating psychosocial outcomes in the long term is essential. Aim: Describe psychosocial outcomes of long term survivors at >…2013 American Transplant Congress
CTLA-4 Ig Prevents Chronic Antibody-Mediated Rejection
Emory Transplant Center, Atlanta
[Background] Chronic rejection of organ transplants remains an unsolved problem in the field of transplantation. Humoral immunity, typically manifesting as alloantibody, is increasingly recognized as…
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