2013 American Transplant Congress
Eculizumab (Anti-C5) for Treatment of Severe Antibody-Mediated Rejection (ABMR) and Recurrent C3 Glomerulonephritis in Renal Allografts: A Single Center Experience
Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
INTRODUCTION: ABMR is a severe form of allograft injury mediated, primarily, by antibody-induced complement activation. Complement activation through the alternate pathway may also result in…2013 American Transplant Congress
Long-Term Impact of a Pancreas Graft on a Previously Transplanted Kidney
Introduction]: While pancreas after kidney (PAK) transplant allow for pre-emptive kidney transplant and reduced waiting times, there is concern that the additional ‘burden' of the…2013 American Transplant Congress
Associations between Clinical, Biochemical Indicators and Anthropometric Measurements with Arterial Stiffness in Renal Transplantation Patients
Purpose: Arterial stiffness is an independent predictor for cardiovascular mortality. In end stage renal disease cardiovascular risk factors such as age, hypertension and diabetes mellitus…2013 American Transplant Congress
Impact of Prospective Monitoring for Donor Specific Antibodies on Renal Transplant Outcomes with Alemtuzumab Induction
MultiOrgan Transplant Program, William Beaumont Hospital, Royal Oak, MI
Alemtuzumab (AL) induction has been associated with an excess of antibody-mediated rejection (AMR). We initiated a steroid-free AL protocol in August 2009 with prospective monitoring…2013 American Transplant Congress
Multicenter Banff Fibrosis Trial: Comparing Visual Assessment of Interstitial Fibrosis in Kidney Biopsies to Computer-Based Image Analysis and Organ Function, The
Interstitial fibrosis (IF) in renal biopsies is a valuable correlate for organ function, provides prognostic information and is a potential end point in trials.From 15…2013 American Transplant Congress
D-MELD, a Powerful Instrument To Optimize Donor-2-Recipient Match. Differences between US and Italy
Previous studies demonstrated in US and Italy that D-MELD can be an instrument to optimize donor-2-recipient match (D2Rm) in Liver Transplantation.To characterize prognostic power, peculiarities…2013 American Transplant Congress
ATP-Competitive mTORC1 and 2 Inhibitors Are a Novel Class of Immunosuppressants That Suppress Allograft Rejection
Surgery, Starzl Transplant Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA
Introduction: The mammalian Target of Rapamycin (mTOR) is the active catalytic subunit of two mTOR-containing complexes – mTOR complex (mTORC) 1 and mTORC2. mTORC1 is…2013 American Transplant Congress
MicroRNA Profiling in Ischemia Reperfusion Injury Performed by Next Generation Sequencing in Human Renal Transplantation
Objectives: In a variety of (patho-) physiological situations microRNAs, small noncoding RNA fragments of 20-24 bp of length, display import post-transcriptional gene regulators. Current pathology…2013 American Transplant Congress
Safety Issues Identified by Proactive Liver Transplant Safety Debriefing
BACKGROUND: Transplantation and, in particular, living donor liver transplantation (LDLT), involves complex systems and process of care that are particularly susceptible to medical errors and…2013 American Transplant Congress
NKp46 Expression Accelerates the Formation of the NK Cell Lytic Immune Synapse
Natural killer cells play an important role in first-line defense against tumor and virus-infected cells. Studies suggest NK cells have a dichotomous role in transplantation…
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