ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Depletion of Both Recipient and Donor Foxp3+ Cells Can Break Tolerance of Skin or Heart Allografts Induced by Mixed Chimerism in Mice

    K. Shinoda, T. Akiyoshi, C. Chase, E. Farkash, P. Russell, J. Madsen, R. Colvin

    Transplant Center, Massachusetts General Hospital, Boston, MA; Department of Pathology, Massachusetts General Hospital, Boston, MA

    Donor-specific transplant tolerance has been achieved by induction of mixed chimerism in both mice and humans and evidence for both deletion and regulation exists. To…
  • 2013 American Transplant Congress

    Infectious Disease Screening of Living Kidney and Liver Donors at a Large Transplant Center

    J. Kim, C. Freise, P. Chin-Hong

    Infectious Diseases, University of California, San Francisco, CA; Transplant Surgery, University of California, San Francisco, CA

    Background: Screening practices for infection in potential living kidney and liver donors have not been standardized among transplant centers despite rare but potentially life-threatening transmitted…
  • 2013 American Transplant Congress

    Is Micro-RNA-122 (miR-122) an Accurate Biomarker for Ischemia-Reperfusion Injury during Liver Transplantation?

    M. Hughes, S. Reddy, M. Brier, C. McClain, C. Jonsson

    Surgery, University of Louisville, Louisville, KY; Medicine, University of Louisville, Louisville, KY; Microbiology and Immunology, University of Louisville, Louisville, KY

    PURPOSE: Liver specific miR-122 has been shown to be potential biomarker for liver injury; however initial production of miR-122 during allograft reperfusion has not been…
  • 2013 American Transplant Congress

    Knowledge and Attitude of the Flemish Primary Care Physician towards Organ Donation and Transplantation

    L. Coucke, E. Snoeck, J. De Maeseneer, I. Haentjens, W. Peersman, X. Rogiers

    Department of Solid Organ Transplantation, Ghent University Hospital, Ghent, Belgium; Department of Family Medicine and Primary Health Care, Ghent University, Ghent, Belgium

    PURPOSE- Primary care physicians might play an important role in the acceptance of organ donation in the population. This would require both a positive attitude…
  • 2013 American Transplant Congress

    Pancreas Transplantation: Personal Factors Associated with Good and Poor Post-Transplant Adaptive Response

    P. Scott, A. Krause, G. Samiran, T. Taber, J. Fridell

    Occupational Therapy, Indiana University, Indianapolis, IN; Department of Family Medicine and Public Health Sciences, Wayne State University of Medicine, Detroit, MI; Department of Medicine, Indiana University Health/Indiana University School of Medicine, Indianapolis, IN

    Notable differences in patient adaptation after pancreas transplant cause some to thrive and return to independent living, while others struggle with emotional and social problems.…
  • 2013 American Transplant Congress

    Evaluation of Cystic Growth in ADPKD Renal Transplant Recipients Following Conversion to an mTOR Inhibitor

    J. Mandabach, M. Rees, H. Elsamaloty, L. Gowharji, L. Twining, S. Khuder, S. Ratnam

    Univ of Toledo Medical Center, Toledo, OH

    Introduction: Previous animal studies of ADPKD suggest sirolimus reduces kidney volume, cyst size and density, and restores overall kidney function as measured by BUN and…
  • 2013 American Transplant Congress

    When Drugs Run Out: Tolerability of Mycophenolate Mofetil and Azathioprine in Lung Transplant Recipients over the Age of Sixty

    M. Hurtik, J. Byrns, N. Patel, M. Harris

    Pharmacy, Emory University Hospital, Atlanta, NC; Pharmacy, Duke University Hospital, Durham, NC

    Triple-drug therapy with tacrolimus, azathioprine (AZA), and prednisone is the standard immunosuppression protocol for lung transplant at Duke University Hospital (DUH). The recent shortage of…
  • 2013 American Transplant Congress

    Graft Loss Rates after Donation after Cardiac Death (DCD) Liver Donation Are Severely Underestimated

    M. DebRoy, G. Klintmalm

    Surgery, Division of Transplantation, UT Southwestern Medical Center, Dallas, TX; Annette C and Harold C. Simmons Transplant Institute at Baylor University Medical Center, Dallas, TX

    Introduction: Organs from DCD donors, particularly livers, have been shown to have outcomes that are inferior to those from donation after brain death (DBD) donors…
  • 2013 American Transplant Congress

    Complement Blockade Prevents Delayed Graft Function in a Non-Human Primate Model of Kidney Allo-Transplantation

    J. Danobeitia, L. Zitur, E. Van Amersfoort, A. D'Alessandro, B. Oortwijn, X. Ma, S. Capuano, K. Brunner, J. Torrealba, L. Fernandez

    Surgery, University of Wisconsin- Madison, Madison, WI; Pharming Group NV, Leiden, Netherlands

    Brain-death (BD) induces an innate immune response that increases the risk of delayed graft function (DGF) and leads to reduced graft survival and increased immunogenicity…
  • 2013 American Transplant Congress

    Incidence of CMV Infection Comparing Two Antiviral Preventative Strategies after Liver Transplantation

    J. Hagopian, T. Horwedel, W. Chapman, L. Bowman

    Pharmacy, Barnes-Jewish Hospital, St. Louis, MO; Surgery, Washington University, St. Louis, MO

    Purpose: CMV remains a common complication of liver transplantation, and its direct and indirect effects contribute greatly to the morbidity and mortality in this patient…
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