2013 American Transplant Congress
Cardiovascular Risk Profile in Children after Renal Transplantation – Introducing the 4C-T Sub-Study
Hannover Medical School, Hannover, Germany; University of Heidelberg, Heidelberg, Germany
Children with chronic kidney disease (CKD) carry an increased cardiovascular risk up to 1000-fold that of the age-matched general population. The 4C-T (Cardiovascular Comorbidity in…2013 American Transplant Congress
Epitope Analysis of col(V)-Specific Th17 Cell Responses in Lung Transplantation Reveals an HLA-DRB1*1501 Bias in Both Patient and Donor
Surgery, UW Madison, Madison, WI
Fibro-obliterative disease of the airways and vessels is a key element of the chronic rejection process after heart and lung transplantation. Th17 cellular immune responses…2013 American Transplant Congress
Assessment of CMV Antiviral Resistance Mutations in Clinical Samples
Viracor-IBT Laboratories, Lee's Summit, MO
Cytomegalovirus (CMV) infections are a major cause of disease among immunocompromised patients. In this population, prolonged antiviral therapy is often necessary to prevent or treat…2013 American Transplant Congress
Harmonization of an LC-MS/MS Assay for Therapeutic Drug Monitoring of Tacrolimus
Background: Monitoring concentrations of tacrolimus in allograft recipients is considered the standard of care. Trough concentrations are regarded as a good surrogate for tacrolimus exposure.…2013 American Transplant Congress
Targeting of mTORC2 in DC Elicits an Enhanced Pro-Inflammatory Profile and Th17 Alloresponse
Mammalian target of rapamycin (mTOR) is an important, yet poorly understood integrative kinase that regulates immune cell function. mTOR functions in two independent complexes,- mTOR…2013 American Transplant Congress
Pronounced Impact of Community Risk Factors on Pre-Transplant Kidney Candidate Processes and Outcomes
IntroductionThere are many potential factors which are associated with patient outcomes beyond traditional clinical and donor characteristics.MethodsWe merged national SRTR data with data aggregated from…2013 American Transplant Congress
Fish Oil Diet Overcomes Genetic Predisposition Restoring Hepatocyte Proliferation in Livers of A20 Heterozygous Mice Following Partial Hepatectomy
Surgery, Beth Israel Deaconess Medical Center - HMS, Boston, MA
Increased free fatty acids (FA) metabolism following partial hepatectomy (PH) is required to meet energy demands of liver regeneration (LR). Impact of dietary lipid intake…2013 American Transplant Congress
French Uncontrolled Donors after Circulatory Arrest (Udcd) Program for Kidney Transplantation: Procurement Procedure Efficiency and 3-Month Survival Results
The national protocol for the uDCD program restricts the no flow period to <30 min and the total warm ischemia time (WIT) to <150 min.…2013 American Transplant Congress
Network Meta-Analysis of Immunosuppressant Regimens in Renal Preservation Following Liver Transplant, A
Background: Long-term exposure to Calcineurin-Inhibitors (CNIs) has been associated with impaired renal function.Objective: To obtain parameter estimates of the relative renal safety of commonly used…2013 American Transplant Congress
Interim Analysis of a Double-Blinded Placebo Controlled Trial of IVIG v. IVIG + Rituximab for Desensitization of Highly-HLA Sensitized (PRA >80%) (HS) Deceased Donor (DD) Candidates
INTRODUCTION: Desensitization protocols (DES) for HS patients are primarily aimed at living-donor recipients. The efficacy of various DES is not established, especially for DD recipients.…
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