2013 American Transplant Congress
Knockdown of Intra-Islet IKKβ by Spherical Nucleic Acid Nanoparticle Conjugates Prevents Host Cytokine-Induced Injury and Enhances Islet Graft Survival
Islet transplantation is a challenging treatment for type-1 diabetic patients. This is due, in part, to the deleterious effects of pro-inflammatory cytokines generated by early…2013 American Transplant Congress
Pigs Deficient in N-Glycolylneuraminic Acid and Galactose α-1,3-Galactose Reduce the Humoral Barrier to Xenotransplantation
Transplant Surgery, Indiana University School of Medicine, Indianapolis, IN
Hyperacute rejection of porcine xenografts in a non-human primate model has been diminished with development of Α1,3-galactosyltransferase knockout (GT-KO) pigs devoid of the galactose Α-1,3-galactose…2013 American Transplant Congress
Pharmaceutical Quality and Bioequivalence Assessment of Generic Mycophenolate Mofetil Tablets
Office of Generic Drugs, FDA, Rockville
Purpose. Mycophenolate Mofetil (MMF) is the most used immunosuppressant in solid organ transplantation. Concerns have been raised about substitution between brand and generic MMF tablets.…2013 American Transplant Congress
Behavioral Reference Points in Organ Utilization
Background: Behavioral reference points partition preferences and define the regions over which an outcome is perceived as a “gain” or “loss.” Whether or not behavioral…2013 American Transplant Congress
Banff Scoring in Early and Late Acute Cellular Rejection Predicts Graft Survival
U of Cincinnati, Cincinnati, OH; Christ Hospital, Cincinnati, OH
Acute rejection (AR) Banff grade (BG) correlates with long-term graft survival, however, previous validation studies did not account for rejection type (acute cellular rejection (ACR)/antibody…2013 American Transplant Congress
Results of Early Corticosteroid Withdrawal under rATG Induction in Hepatitis C Positive Kidney Transplant Recipients: Inferior Yet Improved Outcomes
NY-Presbyterian/Weill Cornell, New York, NY
Hepatitis C virus (HCV) positive kidney transplant recipients face a significant risk of acute rejection (AR), graft loss, new onset diabetes mellitus (NODM), and mortality…2013 American Transplant Congress
Depletion of Both Recipient and Donor Foxp3+ Cells Can Break Tolerance of Skin or Heart Allografts Induced by Mixed Chimerism in Mice
Donor-specific transplant tolerance has been achieved by induction of mixed chimerism in both mice and humans and evidence for both deletion and regulation exists. To…2013 American Transplant Congress
Infectious Disease Screening of Living Kidney and Liver Donors at a Large Transplant Center
Background: Screening practices for infection in potential living kidney and liver donors have not been standardized among transplant centers despite rare but potentially life-threatening transmitted…2013 American Transplant Congress
Is Micro-RNA-122 (miR-122) an Accurate Biomarker for Ischemia-Reperfusion Injury during Liver Transplantation?
PURPOSE: Liver specific miR-122 has been shown to be potential biomarker for liver injury; however initial production of miR-122 during allograft reperfusion has not been…2013 American Transplant Congress
Knowledge and Attitude of the Flemish Primary Care Physician towards Organ Donation and Transplantation
PURPOSE- Primary care physicians might play an important role in the acceptance of organ donation in the population. This would require both a positive attitude…
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