2013 American Transplant Congress
LineageProfiler: A Novel Informatics Tool for Unraveling Transplant Injury
California Pacific Medical Center, San Francisco; University Hospitals Leuven, Leuven, Belgium
Background: A significant challenge in the field of allograft transplantation is the efficient evaluation of tissue-specific immune responses and infiltrating immune cell types.Method: We have…2013 American Transplant Congress
Effect of Normothermic Machine Perfusion (NMP) Using Various Perfusates on the Hepatocellular and Biliary Epithelial Integrity in Porcine Donation after Cardiac Death (DCD) Models, The
Transplant, Cleveland Clinic, Cleveland; Case Western Reserve, Cleveland
Introduction: NMP with sanguineous perfusate was reported to be effective in mitigating IRI of DCD livers. The roles of white blood cells, platelets, and inflammatory…2013 American Transplant Congress
Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes
Cedars-Sinai Heart Institute, Los Angeles, CA
BACKGROUND: In heart transplantation, acute renal failure is not uncommon immediately after heart transplantation. It may be due to pre-existing disease or due to the…2013 American Transplant Congress
Prevention of Early Graft Loss by Proliferator-Activated Receptor-γ Agonist, Pioglitazonoe, in Canine Islet Autotransplantation
Purpose: Approximately 50% of islet grafts are destroyed within 72 hours after pancreatic islet transplantation (PITx) due to non-specific inflammatory responses. Previously, we reported that…2013 American Transplant Congress
Comparative Effectiveness of Rabbit Anti-Thymocyte Globulin vs. Interleukin-2 Receptor Blockers in Deceased Donor Kidney Transplants with Delayed Graft Function, The
Department of Medicine, Division of Nephrology, University of Toronto, Toronto, ON, Canada
Background: To date, studies addressing outcomes of depleting (i.e., rabbit anti-thymocyte globulin or rATG) vs. non-depleting (i.e., IL-2 receptor blocker or IL2RB) induction strategies in…2013 American Transplant Congress
Histopathologic Scoring and Outcomes in Transplant Glomerulopathy (TG)
Introduction: TG is associated with poor allograft survival and there are limited treatment options. Some report improved outcomes with rituximab. Histopathologic scoring might predict prognosis…2013 American Transplant Congress
Increasing HLA DR Mismatches Is Associated with Inferior Kidney Allograft Outcome in Low Immune Risk Living Donor Kidney Transplant Recipients
Background: HLA DR mismatches (MM) have been shown to negatively influence kidney allograft outcomes in historical cohorts. We examined whether this effect persists in the…2013 American Transplant Congress
Classification of Kidney Transplant Recipients Using a Combination of Estimated GFR and Albuminuria Reflects Prognosis
The 2002 NKF-K/DOQI Chronic Kidney Disease (CKD) classification scheme, based largely on the estimated glomerular filtration rate (eGFR), has been criticized for failing to adequately…2013 American Transplant Congress
Effect of Vasodilators on Organ Function during Normothermic Machine Perfusion of Porcine DCD Liver, The
Cleveland Clinic, Cleveland, OH; Case Western Reserve University, Cleveland, OH
Introduction: Shortage of donor livers and prolonged wait list mortality has lead to the need of using extended criteria donors. Donation after Cardiac Death (DCD)…2013 American Transplant Congress
Risk Factors for Graft Failure and Death in Elderly (>65 Years Old) Kidney Transplant Recipients
Background:Kidney transplantation outcomes in the elderly have been favorable but detailed accounts of these outcomes from non-registry data is limited.Purpose:The purpose of this study was…
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