ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Factors Associated with Physical and Mental Quality of Life in Kidney Transplant Recipients Currently ≥ 50 Years Old

    A. Faravardeh, S. Jackson, A. Matas, C. Gross, H. Ibrahim

    Division of Renal Diseases and Hypertension, University of Minnesota, Minneapolis, MN; Department of Surgery, University of Minnesota, Minneapolis, MN; School of Nursing, University of Minnesota, Minneapolis, MN

    Background:Kidney transplantation is becoming more common in older patients. Quality of life (QOL) in these patients who are usually burdened with many comorbid conditions has…
  • 2013 American Transplant Congress

    Ischemia-Induced ATF6 Upregulation Is a Key Factor in Liver Pro-Inflammatory Immune Response Against Ischemia Reperfusion

    J. Rao, S. Yue, J. Zhu, R. Bussutil, J. Kupiec-Weglinski, L. Lu, Y. Zhai

    Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA; Liver Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiansu Province, China

    Background and Aim: We have shown previously that endoplasmic reticulum (ER) stress may function in synergy with TLR4 in liver IRI to facilitate pro-inflammatory immune…
  • 2013 American Transplant Congress

    Creatinine as a Marker of Rejection Reversal in Recipients with Post-Treatment Biopsies

    A. Jantz, S. Patel, L. Moore, L. Gaber, R. Knight, A. Gaber

    The Methodist Hospital, Houston, TX

    It is debatable whether creatinine can serve as a surrogate marker of rejection reversal. The purpose of the current study was to evaluate the change…
  • 2013 American Transplant Congress

    LineageProfiler: A Novel Informatics Tool for Unraveling Transplant Injury

    N. Salomonis, M. Naesens, T. Sigdel, M. Sarwal

    California Pacific Medical Center, San Francisco; University Hospitals Leuven, Leuven, Belgium

    Background: A significant challenge in the field of allograft transplantation is the efficient evaluation of tissue-specific immune responses and infiltrating immune cell types.Method: We have…
  • 2013 American Transplant Congress

    Effect of Normothermic Machine Perfusion (NMP) Using Various Perfusates on the Hepatocellular and Biliary Epithelial Integrity in Porcine Donation after Cardiac Death (DCD) Models, The

    A. Nassar, Q. Liu, K. Farias, C. Tom, G. D'Amico, A. Bennett, K. Abu-Elmagd, C. Miller, J. Fung, C. Quintini

    Transplant, Cleveland Clinic, Cleveland; Case Western Reserve, Cleveland

    Introduction: NMP with sanguineous perfusate was reported to be effective in mitigating IRI of DCD livers. The roles of white blood cells, platelets, and inflammatory…
  • 2013 American Transplant Congress

    Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes

    A. Osborne, J. Patel, M. Kittleson, M. Rafiei, D. Chang, L. Czer, J. Kobashigawa

    Cedars-Sinai Heart Institute, Los Angeles, CA

    BACKGROUND: In heart transplantation, acute renal failure is not uncommon immediately after heart transplantation. It may be due to pre-existing disease or due to the…
  • 2013 American Transplant Congress

    Prevention of Early Graft Loss by Proliferator-Activated Receptor-γ Agonist, Pioglitazonoe, in Canine Islet Autotransplantation

    Y. Asahi, K. Yamashita, M. Watanabe, M. Ogura, H. Ono, E. Handly, S. Emoto, A. Nagatsu, T. Yoshida, Y. Koshizuka, H. Kamachi, A. Taketomi, S. Todo

    Surgery I, Hokkaido University, Sapporo, Hokkaido, Japan; Transplant Surgery, Hokkaido University, Sapporo, Hokkaido, Japan

    Purpose: Approximately 50% of islet grafts are destroyed within 72 hours after pancreatic islet transplantation (PITx) due to non-specific inflammatory responses. Previously, we reported that…
  • 2013 American Transplant Congress

    Comparative Effectiveness of Rabbit Anti-Thymocyte Globulin vs. Interleukin-2 Receptor Blockers in Deceased Donor Kidney Transplants with Delayed Graft Function, The

    A. Oweis, J. Zaltzman, J. Kim

    Department of Medicine, Division of Nephrology, University of Toronto, Toronto, ON, Canada

    Background: To date, studies addressing outcomes of depleting (i.e., rabbit anti-thymocyte globulin or rATG) vs. non-depleting (i.e., IL-2 receptor blocker or IL2RB) induction strategies in…
  • 2013 American Transplant Congress

    Histopathologic Scoring and Outcomes in Transplant Glomerulopathy (TG)

    R. Najjar, J. Kahwaji, D. Kancherla, A. Peng, R. Villicana, S. Jordan, A. Vo, M. Haas

    Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; Pathology, Cedars-Sinai Medical Center, Los Angeles, CA

    Introduction: TG is associated with poor allograft survival and there are limited treatment options. Some report improved outcomes with rituximab. Histopathologic scoring might predict prognosis…
  • 2013 American Transplant Congress

    Increasing HLA DR Mismatches Is Associated with Inferior Kidney Allograft Outcome in Low Immune Risk Living Donor Kidney Transplant Recipients

    S. Lynch, K. Tinckam, J. Kim

    Department of Medicine, Division of Nephrology, Toronto General Hospital, University of Toronto, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, Toronto General Hospital, University of Toronto, Toronto, ON, Canada

    Background: HLA DR mismatches (MM) have been shown to negatively influence kidney allograft outcomes in historical cohorts. We examined whether this effect persists in the…
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