2013 American Transplant Congress
Chemokine Responses as Surrogates of CMV Cell-Mediated Immunity and Predictors of Outcomes in Transplant Recipients
Background: CMV-specific T-cell responses are crucial to protection of transplant patients against CMV viremia and disease. While studies have centered on CMV cytotoxic T-cells, using…2013 American Transplant Congress
Role of Microcirculatory Integrity in DCD Ex-Vivo Organ Perfusion
Cleveland Clinic, Cleveland, OH; Case Western Reserve University, Cleveland, OH
Introduction: Normothermic machine perfusion (NMP) represents a new preservation modality that could allow for better preservation of marginal donors such as donor after cardiac death…2013 American Transplant Congress
Comparative Effectiveness of Rabbit Anti-Thymocyte Globulin vs. Interleukin-2 Receptor Blockers in Deceased Donor Kidney Transplants with Delayed Graft Function, The
Department of Medicine, Division of Nephrology, University of Toronto, Toronto, ON, Canada
Background: To date, studies addressing outcomes of depleting (i.e., rabbit anti-thymocyte globulin or rATG) vs. non-depleting (i.e., IL-2 receptor blocker or IL2RB) induction strategies in…2013 American Transplant Congress
Histopathologic Scoring and Outcomes in Transplant Glomerulopathy (TG)
Introduction: TG is associated with poor allograft survival and there are limited treatment options. Some report improved outcomes with rituximab. Histopathologic scoring might predict prognosis…2013 American Transplant Congress
Increasing HLA DR Mismatches Is Associated with Inferior Kidney Allograft Outcome in Low Immune Risk Living Donor Kidney Transplant Recipients
Background: HLA DR mismatches (MM) have been shown to negatively influence kidney allograft outcomes in historical cohorts. We examined whether this effect persists in the…2013 American Transplant Congress
Classification of Kidney Transplant Recipients Using a Combination of Estimated GFR and Albuminuria Reflects Prognosis
The 2002 NKF-K/DOQI Chronic Kidney Disease (CKD) classification scheme, based largely on the estimated glomerular filtration rate (eGFR), has been criticized for failing to adequately…2013 American Transplant Congress
Effect of Vasodilators on Organ Function during Normothermic Machine Perfusion of Porcine DCD Liver, The
Cleveland Clinic, Cleveland, OH; Case Western Reserve University, Cleveland, OH
Introduction: Shortage of donor livers and prolonged wait list mortality has lead to the need of using extended criteria donors. Donation after Cardiac Death (DCD)…2013 American Transplant Congress
Risk Factors for Graft Failure and Death in Elderly (>65 Years Old) Kidney Transplant Recipients
Background:Kidney transplantation outcomes in the elderly have been favorable but detailed accounts of these outcomes from non-registry data is limited.Purpose:The purpose of this study was…2013 American Transplant Congress
Predicting Graft Failure in Kidney Transplant Patients: A Combined Clinical/Molecular Approach to Analyzing Biopsies
We combined an existing dataset with new data from a multi-centre international collaboration (INTERCOM), to predict graft loss in a patient population undergoing kidney transplant…2013 American Transplant Congress
Rapamycin and CTLA4-Ig Demonstrate Age-Specific Effects on Transplant Outcome and Immune Responses
Surgery, Brigham and Women's Hospital, Boston, MA
Elderly patients constitute the fastest growing proportion of organ transplant recipients. Whether immunosuppression needs to be adapted in an age-dependent manner or if immunosuppressants have…
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