ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Role of Microcirculatory Integrity in DCD Ex-Vivo Organ Perfusion

    Q. Liu, A. Nassar, K. Farias, C. Tom, A. Bennett, G. D'Amico, K. Abu-Elmagd, J. Fung, C. Miller, C. Quintini

    Cleveland Clinic, Cleveland, OH; Case Western Reserve University, Cleveland, OH

    Introduction: Normothermic machine perfusion (NMP) represents a new preservation modality that could allow for better preservation of marginal donors such as donor after cardiac death…
  • 2013 American Transplant Congress

    Locally-Delivered CD4+CD25highFoxp3+ Regulatory T Cells Combined with Systemic KRP203 Therapy Induces Tolerance to Islet Allografts

    C. Baum, M. Khattar, R. Deng, B. Kahan, P. Schroder, T. Phan, L. Rutzky, S. Stepkowski

    Medical Microbiology & Immunology, University of Toledo College of Medicine, Toledo, OH; Division of Immunology & Organ Transplantation, Department of Surgery, University of Texas Medical School, Houston, TX

    Background: KRP203, a structural FTY720 analog, has 5-fold greater selectivity for binding to sphingosine-1-phosphate receptor 1 (S1PR1) versus S1PR3 and 100-fold greater selectivity versus S1PR2…
  • 2013 American Transplant Congress

    Causes of Rejection and Non Utilization of Live Liver Donors: A Single Center Experience

    S. Kashkoush, M. Akhtar, B. Hegab, S. Alshlwi, W. O'Hali, K. Abdullah

    Hepatobiliary Surgery and Liver Transplantation, King Fahad National Guard Hospital, Riyadh, Saudi Arabia

    Background: Proper selection of live liver donors is crucial for both donor safety and transplant recipient outcome. Non utilization of possible live donors is multifactorial…
  • 2013 American Transplant Congress

    Improving Value after Pediatric Liver Transplant: Discharge Practices of High-Performing Centers

    B. Kelly, M. Englesbe, J. Bucuvalas, W. Andrews, J. Mitchell, R. Anand, W. Yin, J. Magee, G. Mazariegos, S. Horslen

    SPLIT Quality Improvement Committee, Nashville; University of Michigan, Ann Arbor; University of Cincinnati, Cincinnati; Children's Mercy Hospital, Kansas City; EMMES Corporation, Rockville; Children's Hospital of Pittsburgh, Pittsburgh; University of Washington, Seattle

    We sought to improve value (outcomes/cost) for the initial hospitalization after pediatric liver transplantation (LT) by identifying variation in length of stay (LOS), a highly…
  • 2013 American Transplant Congress

    Obesity Does Not Adversely Affect the Outcomes of Kidney Transplantation

    I. Begov, S. Akkina, E. Benedetti, I. Tang

    Medicine, University of Illinois Medical Center, Chicago, IL; Surgery, University of Illinois Medical Center, Chicago, IL

    Obese patients with end stage kidney disease encounter difficulties obtaining kidney transplantation (KTx) because of concern for shorter graft and patient survival. We examined the…
  • 2013 American Transplant Congress

    Combined Induction Therapy with Rabbit Antithymocyte Globulin (rATG) and Rituximab (RTX) in Highly Sensitized Kidney Recipients: Long-Term Outcomes

    M. Laftavi, S. Patel, R. Kohli, M. Zachariah, L. Feng, M. Said, M. Dayton, O. Pankewycz

    Surgery, SUNY at Buffalo, Buffalo, NY; Medicine, SUNY at Buffalo, Buffalo, NY

    Despite the use of T cell depleting induction therapy, the incidence of acute humoral (AMR) and cellular (ACR) rejection remains high and the graft survival…
  • 2013 American Transplant Congress

    Survival Benefit of a Third Kidney Transplant, The

    R. Redfield, A. Wood, P. Abt, M. Levine

    Department of Transplant Surgery, University of Pennsylvania, Philadelphia, PA

    Background: The size of the kidney wait list as well as the waiting time is increasing in the US. Given the current shortage of renal…
  • 2013 American Transplant Congress

    Factors Associated with Physical and Mental Quality of Life in Kidney Transplant Recipients Currently ≥ 50 Years Old

    A. Faravardeh, S. Jackson, A. Matas, C. Gross, H. Ibrahim

    Division of Renal Diseases and Hypertension, University of Minnesota, Minneapolis, MN; Department of Surgery, University of Minnesota, Minneapolis, MN; School of Nursing, University of Minnesota, Minneapolis, MN

    Background:Kidney transplantation is becoming more common in older patients. Quality of life (QOL) in these patients who are usually burdened with many comorbid conditions has…
  • 2013 American Transplant Congress

    Ischemia-Induced ATF6 Upregulation Is a Key Factor in Liver Pro-Inflammatory Immune Response Against Ischemia Reperfusion

    J. Rao, S. Yue, J. Zhu, R. Bussutil, J. Kupiec-Weglinski, L. Lu, Y. Zhai

    Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA; Liver Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiansu Province, China

    Background and Aim: We have shown previously that endoplasmic reticulum (ER) stress may function in synergy with TLR4 in liver IRI to facilitate pro-inflammatory immune…
  • 2013 American Transplant Congress

    Creatinine as a Marker of Rejection Reversal in Recipients with Post-Treatment Biopsies

    A. Jantz, S. Patel, L. Moore, L. Gaber, R. Knight, A. Gaber

    The Methodist Hospital, Houston, TX

    It is debatable whether creatinine can serve as a surrogate marker of rejection reversal. The purpose of the current study was to evaluate the change…
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