ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Over-Expression of miR-499 within Donor Heart Attenuates Cardiac Allograft Vasculopathy

    X. Zhang, Z. Chen, X. Chen, P. Li, J. Yang

    Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Institute of Zoology, Chinese Academy of Sciences, Beijing, China

    Cardiac allograft vasculopathy (CAV) is a major limiting factor in the long-term success of heart transplantation. Ischemia-reperfusion injury plays a critical role in initiation of…
  • 2013 American Transplant Congress

    Novel Monitoring Panel for Tolerance-Inducing Effects of Extracorporal Photopheresis

    M. Dieterlen, H. Bittner, S. Dhein, F. Mohr, M. Barten

    Clinic for Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany; Dept. Cardiothoracic Transplantation and Advanced Cardiac Surgery, Florida Hospital Orlando, Orlando

    Goal: Extracorporal photopheresis (ECP) has been used as a therapeutic option for acute and chronic rejection after transplantation. Tolerance-inducing effects of ECP after transplantation are…
  • 2013 American Transplant Congress

    TLR2 Signaling in Epithelial Cells Initiates Sterile Tissue Inflammation through Recruitment of NK Cells in Renal Ischemia Reperfusion Injury

    H. Cho, B. Kwon, J. Lee, H. Cha, H. Kim, A. Kim, S. Koo, R. Mittler

    Department of Surgery, Ulsan University Hospital,College of Medicine, University of Ulsan, Ulsan, Republic of Korea; School of Biological Sciences, University of Ulsan, Ulsan, Republic of Korea; Department of Internal Medicine, Ulsan University Hospital,College of Medicine, University of Ulsan, Ulsan, Republic of Korea; Biomedical Research Center, Ulsan University Hospital,College of Medicine, University of Ulsan, Ulsan, Republic of Korea; Department of Pathology, Ulsan University Hospital,College of Medicine, University of Ulsan, Ulsan, Republic of Korea; Department of Surgery and Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA

    It is well recognized that damage-associated molecular patterns (DAMPs) released from damaged kidney cells initiate post-ischemic inflammation, an essential step in the progression of kidney…
  • 2013 American Transplant Congress

    Alemtuzumab for Induction Therapy for Small Bowel Transplantation

    T. Vowinkel, J. Hoelzen, C. Anthoni, H. Schmidt, N. Senninger, H. Wolters

    Department of General and Visceral Surgery, University Hospital Muenster, Muenster, Germany; Clinic for Transplantation Medicine, University Hospital Muenster, Muenster, Germany

    IntroductionSmall bowel transplantation can be performed for short bowel syndrome. The ideal immunosuppressive regimen after small bowel transplantation still needs to be defined. Here we…
  • 2013 American Transplant Congress

    New-Onset Diabetes and Glucose Regulation Are Significant Determinants of Left Ventricular Hypertrophy

    M. Erkmen Uyar, S. Sezer, Z. Bal, E. Tutal, B. Gurlek Demirci, E. Hasdemir, T. Colak, F. Ozdemir Acar, M. Haberal

    Department of Nephrology, Baskent University, Ankara, Turkey; Department of Internal Medicine, Baskent University, Ankara, Turkey; Department of Nephrology, Baskent University, Istanbul, Turkey; Department of General Surgery, Baskent University, Ankara, Turkey

    Purpose: . Arterial stiffness has a pivotal role in the genesis of high blood pressure (SBP), increased left ventricular hypertrophy (LVH), and consequently CV mortality.…
  • 2013 American Transplant Congress

    Health-Related Quality of Life in the Pre-Transplant Candidate Low MELD for End-Stage Liver Disease (MELD) Score: A Pilot Study

    R. Duke

    Transplant Surgery, Northwestern Memorial Hospital, Chicago, IL

    Cadaveric liver organ allocation is based on the model for end-stage liver disease (MELD) score. Those with low MELD scores (≤ 15) are considered to…
  • 2013 American Transplant Congress

    Excellent Results of Living-Related Renal Transplant Recipients Treated with High-Dose Mizoribine – Two Years Result of a Japanese Multicenter Study

    N. Yoshimura, K. Uchida, K. Yuzawa, Y. Fukuda, K. Akioka, M. Fujisawa, S. Lto, T. Nakatani, T. Horimi, H. Ushigome, K. Nishimura

    Prefectural University of Medicine, Kyoto, Japan; Aichi Medical University, Nagakute, Aichi, Japan; Mito Medical Center, Mito, Ibagaki, Japan; Koseiren Hiroshima General Hospital, Hatsukaichi, Hiroshima, Japan; Omihachiman Community Medical Center, Omihachiman, Shiga, Japan; Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan; Gifu University School of Medicine, Gifu, Japan; Osaka City University Graduate School of Medicine, Osaka, Japan; Kochi Health Sciences Center, Kochi, Japan; Hyogo Prefectural Nishinomiya Hospital, Nishinomiya, Hyogo, Japan

    (Aims) Mizoribine (MZR) has been developed as an immunosuppressive agent, but has a less potent immunosuppressive effect up to 3 mg/kg/day. The widespread use of…
  • 2013 American Transplant Congress

    Critical Analysis of Valganciclovir Dosing and Renal Function on the Development of CMV Infection in Kidney Transplantation

    M. Posadas Salas, D. Taber, E. Chua, B. Thomas

    Department of Medicine, Division of Nephrology and Hypertension, Medical University of South Carolina, Charleston, SC; Department of Pharmacy, Medical University of South Carolina, Charleston, SC

    Purpose: To evaluate factors that impact the development of CMV infection in renal transplant recipients.Background: Cytomegalovirus (CMV) infection is one of the most common and…
  • 2013 American Transplant Congress

    Behavior of ADAMTS13 and Von Willebrand Factor Levels in Patients after Living Donor Liver Transplantation

    N. Takahashi, H. Wada, M. Usui, Y. Iizawa, R. Sato, T. Hujii, A. Tanemura, N. Kuriyama, Y. Azumi, I. Osawa, M. Kishiwada, S. Mizuno, H. Sakurai, M. Tabata, S. Isaji

    Hepatobiliary Pancreatic and Transplant Surgery, Mie University Graduate School of Medicine, Tsu, Mie, Japan; Department of Molecular and Laboratory Medicine, Mie University Graduate School of Medicine, Tsu, Mie, Japan

    Introduction : Thrombotic microangiopathy (TMA) is one of the important complications occurring after liver transplantation (LT), and it is suggested that a Von Willebrand factor…
  • 2013 American Transplant Congress

    Impact of Donor-Specific Anti-HLA and Anti-Angiotensin-II Type 1 Receptor Antibodies on Graft Fibrosis after Immunosuppression Withdrawal in Pediatric Liver Transplantation

    H. Oe, Y. Uchida, A. Yoshizawa, H. Hirao, M. Taniguchi, E. Maruya, T. Maekawa, S. Uemoto, P. Terasaki

    Surgery, Kyoto University, Kyoto, Japan; Transfusion Medicine and Cell Therapy, Kyoto University Hospital, Kyoto, Japan; Paul I. Terasaki Foundation Laboratory, Los Angeles, CA

    Pediatric living-donor liver transplant (LDLT) recipients can often exhibit a reduction or cessation of immunosuppression (IS); over the long term, a high incidence of progressive…
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