2013 American Transplant Congress
Invasive Fungal Infection in Liver Transplant Recipients – Focus on Underestimated Risk Factors Associated with In-Hospital Mortality
Departments of Surgery and Anaestesiology, University Hospital, Regensburg, Germany
Background: Invasive fungal infections (IFIs) in liver transplant recipients are associated with increased mortality. Although the risk factors for developing IFIs have been extensively investigated,…2013 American Transplant Congress
Population Pharmacokinetics of Tofacitinib in De Novo Kidney Transplant Patients
Introduction: Tofacitinib is a novel, oral Janus kinase inhibitor being investigated as a targeted immunomodulator. Tofacitinib achieved comparable rate of biopsy-proven acute rejection and improved…2013 American Transplant Congress
Donor Derived Transmission Events in 2012: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC)
The OPTN DTAC, a multidisciplinary committee, evaluates potential donor derived transmission events (PDDTE), including infections (I) & malignancies (M), to assess for donor transmitted events.Methods:…2013 American Transplant Congress
Lung Recipients with Post-Transplant Lung Cancer and Comparison with Other Organ Recipients
The burden and impact of lung cancer among transplant recipients and a comparison between recipients of lung and other organs has been studied in small…2013 American Transplant Congress
Sepsis after Renal Transplantation: Clinical, Microbiological, and Immunological Characteristics
As immunosuppressive drugs and allograft survival have improved over the last decades, infection has become the main hurdle of patient survival and long-term allograft function…2013 American Transplant Congress
Severe Sepsis after Renal Transplantation: The Importance of HLA-B Matching
Sepsis remains one of the most common causes of death among renal transplant recipients. Particular risk factors, however, are poorly described in this patient population,…2013 American Transplant Congress
Mature Dendritic Cells Are Superior Stimulator Cells for Expansion of Human Alloreactive Regulatory T Cells
IntroductionAntigen (Ag)-specific regulatory T cells (Tregs) have a great therapeutic clinical potential. However, large numbers are needed before Tregs can be used as cellular immunotherapy…2013 American Transplant Congress
Alloantigen-Specific Tregs Can Be Identified by Activation-Induced CD154 Expression
IntroductionAntigen (Ag)-specific T cells can be recognized using cell surface expression of markers specifically induced upon T cell receptor interaction with peptides presented in the…2013 American Transplant Congress
CD137, a Marker To Detect the Total Alloreactive T Cell Compartment?
IntroductionAlloreactive T cells are important mediators of rejection or tolerance of the transplanted organ. Detection and isolation of viable alloreactive T cells at the single…2013 American Transplant Congress
Factors Affecting the Humoral Response to HLA Antigens
Medicine, Johns Hopkins University School of Medicine, Baltimore, MD
Post-transplant antibody (Ab) to donor HLA is associated with reduced graft survival, but it is unknown if some HLA antigens are more likely to induce…
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