ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Three-Year Safety and Efficacy Outcomes in Kidney Transplant Patients Randomized to Steroid Avoidance or Maintenance Steroids with Early Intensified Dosing of Enteric-Coated Mycophenolate Sodium: The INFINITY Study

    A. Thierry, G. Mourad, M. Büchler, N. Kamar, F. Villemain, A. Heng, Y. Le Meur, G. Choukroun, O. Toupance, C. Legendre, P. Le Pogamp, M. Kessler, P. Merville, B. Moulin, S. Quéré, A. Lécuyer, F. Di Giambattista, G. Touchard

    Service de Néphrologie et Transplantation Rénale, Hôpital La Milétrie, Poitiers, France; , For the INFINITY Study Group, France; Novartis Pharma SAS, Rueil-Malmaison, France

    Short-term intensified enteric-coated mycophenolate sodium (EC-MPS) dosing may facilitate steroid avoidance (SA) after kidney transplantation.Methods. De novo kidney transplant recipients at low immunological risk (PRA…
  • 2013 American Transplant Congress

    Influence of Plasmapheresis on the Concentration of Soluble Urokinase Receptor (suPAR) in Patients with Focal Segmental Glomerulosclerosis (FSGS)

    O. Staeck, D. Khadzhynov, F. Halleck, M. Duerr, M. Naik, L. Liefeld, I. Lieker, T. Slowinski, H. Peters, H. Neumayer, K. Budde

    Department of Nephrology, Charité Universitaetsmedizin Berlin, Berlin, Germany

    Background: suPAR is elevated in patients (pts) with FSGS. Increased levels were associated with recurrence in transplanted kidneys. Previous studies suggested a causative role in…
  • 2013 American Transplant Congress

    Integrated Analysis of MHC Class I-Like (MICA, HLA-E and EPCR) Genetic Diversity in Kidney Transplant Donors and Graft’s Endothelial Cell Phenotype

    B. Charreau, N. Gerard, P. Tonnerre, P. Gavlovsky, A. Pabois, C. Guitton

    INSERM UMR1064, Nantes, France

    Although, there is evidence for a role of MICA, HLA-E and EPCR in vascular transplant biology and immunology, genotyping is not routinely achieved and correlation…
  • 2013 American Transplant Congress

    Differential Effects of the Innate vs. Adaptive Immunity in Lysing Human Renal Tubular Epithelial Cells

    M. Demmers, S. Korevaar, J. IJzermans, M. Betjes, W. Weimar, A. Rowshani, C. Baan

    Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands; Surgery, Erasmus Medical Center, Rotterdam, Netherlands

    Introduction At present, the relative contribution of the innate and adaptive cytotoxic immunity to human renal tubular epithelial cell injury (TECs) remains poorly defined. Cells…
  • 2013 American Transplant Congress

    Measuring Kidney Patients' Motivation To Pursue Living Donor Kidney Transplant: Development of Stage of Change, Decisional Balance and Self-Efficacy Measures

    M. Robbins, A. Paiva, L. Davis, S. Hyland, L. Brick, J. Peipert, E. Schenk, N. Amoyal, K. Baldwin, A. Waterman

    University of Rhode Island, Kingston, RI; Washington University School of Medicine, St. Louis, MO

    Educational interventions that increase patient motivation to pursue living donor kidney transplant (LDKT), positive attitudinal change, and self-efficacy have been shown to increase LDKT rates,…
  • 2013 American Transplant Congress

    Effect of Belatacept on Follicular Helper T Cell and Humoral Response in Sensitized Rhesus Macaques, The

    J. Kwun, E. Page, A. Gibby, N. Iwakoshi, S. Knechtle

    Surgery, Emory University, Atlanta, GA

    [Background] The generation of high affinity antibody and B cell memory requires the interaction of antigen-specific B and T cells in lymphoid follicles and the…
  • 2013 American Transplant Congress

    MnTMPyp, a Selective Superoxide Dismutase Mimetic, Reduces Oxidative Stress in Brain Dead Donors

    D. Hoeksma, L. van Dullemen, P. Ottens, S. Veldhuis, R. Ploeg, H. Leuvenink

    Surgery, University Medical Center Groningen, Groningen, Netherlands; Surgery, University of Oxford, Oxford, United Kingdom

    Renal allografts retrieved from brain dead donors show inferior transplant outcomes compared to living donor grafts. Brain death (BD) leads to immunological activation and hemodynamic…
  • 2013 American Transplant Congress

    Conversion from Tacrolimus (TAC) to Sirolimus (SRL)-Based Immunosuppressive Regimen in Kidney Transplant Recipients: 2 Years Results

    H. Tedesco, E. Neto, V. Garcia, F. Continieri, D. Carvalho, M. Abbud, J. Medina- Pestana

    Nephrology Division, Hospital do Rim e Hipertensao, São Paulo, Brazil; Hospital das Clinicas FMUSP, São Paulo, Brazil; Santa Casa, Porto Alegre, Brazil; Hospital Evangélico, Curitiba, Brazil; Hospital Geral do Bonsucesso, Rio de Janeiro, Brazil; Faculdade de Medicina, Rio Preto, Brazil

    Introduction: This multicenter prospective study evaluated renal function of kidney transplant (KT) recipients randomized after the transplant surgery to undergo planned conversion from TAC to…
  • 2013 American Transplant Congress

    Prolonged Extraction Time of Kidneys from Deceased Donors Impacts Function

    A. Osband, N. James, C. Keating, D. Segev

    Kidney/Pancreas Transplant Surgery, Robert Wood Johnson Medical School, New Brunswick, NJ; Surgery, Johns Hopkins University School of Medicine, Baltimore, MD; New Jersey Sharing Network, New Providence, NJ

    Background: Cold and warm ischemia times are known to impact DGF (delayed graft function) rates and long-term allograft survival following deceased donor kidney transplantation. We…
  • 2013 American Transplant Congress

    Micro RNA Biomarker Candidates for Vascular Invasion in Hepatocellular Carcinoma

    C. Barry, K. Chuang, M. Dokus, C. Whitney-Miller, M. Orloff

    Transplant Surgery, University of Rochester, Rochester, NY; Pathology, University of Rochester, Rochester, NY

    INTRODUCTION: The presence of vascular invasion is known to be a strong predictor of hepatocellular carcinoma (HCC) recurrence after resection or transplant, but no clinically…
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