ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Human Thrombomodulin Regulates Complement Activation as Well as Coagulation in Xenoimmune Response

    H. Kim, J. Jeong, T. Koo, H. Jeon, H. Ro, M. Kim, J. Park, I. Yun, J. Yang, C. Ahn

    Seoul National University College of Medicine, Transplantation Research Institute, Seoul, Korea; Seoul National University Hospital, Transplantation Center, Seoul, Korea; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; Department of Internal Medicine, Gachon Gil Medical Center, Incheon, Korea; Department of Internal Medicine, Korea University Anam Hospital, Seoul, Korea; Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea; Department of Surgery, Konkuk University School of Medicine, Seoul, Korea

    Introduction: Coagulation response is an important obstacle for a long-term xenograft survival. Thrombomodulin (TBM) has critical anticoagulant and anti-inflammatory effects as a component of the…
  • 2013 American Transplant Congress

    Assessment of the Time-Dependent Effect of Blood Pressure on the Risk of Graft Failure in Kidney Transplant Recipients Using a Marginal Structural Model, An

    N. Fozdar, O. Famure, Y. Li, J. Kim

    Medicine (Nephrology), Toronto General Hospital, University of Toronto, Toronto, ON, Canada

    Background: The relationship between blood pressure (BP) and kidney function, as well as their joint influence on graft failure, is complex. This study aims to…
  • 2013 American Transplant Congress

    Preoperative Amino Acid Free Diet Protects Against Hepatic Ischemia Reperfusion Injury, A

    T. Saat, T. van Ginhoven, M. Verweij, L. van der Laan, J. IJzermans, R. de Bruin

    Laboratory for Experimental Transplantation and Intestinal Surgery (LETIS), Erasmus University Medical Center, Rotterdam, Netherlands

    Background: Ischemia and reperfusion (I/R) injury is a serious and common complication after liver surgery and transplantation. We previously showed that three days of preoperative…
  • 2013 American Transplant Congress

    Role of Single-Port Laparoscopy in Donor Right Hepatectomy for Living Donor Liver Transplantation

    Y. You, H. Choi, G. Na, J. Han, E. Kim, S. Lee, T. Hong, Y. Yoon, S. Kim, D. Kim

    HBP Surgery, General Surgery, The Catholic University, Seoul St. Mary's Hospital, Seoul, Republic of Korea; Gerenal Surgery, The Catholic University, Incheon St. Mary's Hospital, Incheon, Republic of Korea; General Surgery, The Catholic University, Daejeon St. Mary's Hospital, Daejeon, Republic of Korea

    BackgroundLaparoscopic liver surgery has rapidly gained attention worldwide. Since 2008, we have used laparoscopic technique for the donor right hepatectomy in living-donor liver transplantation and…
  • 2013 American Transplant Congress

    Comparison of Gene Expression in Heart Beating and Non Heart Beating Donor Kidney, A

    T. Saat, D. Susa, H. Roest, N. Kok, S. van den Engel, J. IJzermans, R. de Bruin

    Experimental Surgery, Erasmus University Medical Centre, Rotterdam, Netherlands

    The superior long-term survival of kidneys from living donors (LD) compared to brain death (BD) or non heart beating (NHB) donors is now well established.…
  • 2013 American Transplant Congress

    T-Cell Mediated Rejections Do Not Induce De Novo Donor Specific Antibodies in Non-Sensitized Kidney Transplant Recipients: A Longitudinal Cohort Analysis

    J. Chemouny, C. Suberbielle, A. Loupy, C. Legendre, D. Anglicheau

    Transplantation Rénale Adulte, Hôpital Necker-Enfants Malades/Assistance Publique-Hôpitaux de Paris, Paris, France, Metropolitan; Laboratoire Régional d'Histocompatibilité, Hôpital Saint-Louis/Assistance Publique-Hôpitaux de Paris, Paris, France, Metropolitan

    Humoral allo-immunity is a major determinant of kidney graft survival, and de novo donor specific anti-HLA antibodies (dnDSA) are associated with an increased risk of…
  • 2013 American Transplant Congress

    MICA A5.1 Mutation Is an Immunodominant Factor, Promoting MICA Expression on Graft Endothelial Cells and MICA Alloimmunisation, and a Potential Risk Factor for Transplant Survival

    B. Charreau, P. Tonnerre, N. Gerard, C. Poli, S. Allard, S. Cury, C. Bressollette, A. Cesbron-Gautier

    INSERM UMR1064, Nantes, France; Laboratoire HLA, Etablissement Français du Sang, Nantes, France; EA4271, Université de Nantes, Nantes, France

    Clinical findings suggest a role for donor MHC class I-related chain A (MICA) antigens expressed on transplant endothelial cells (ECs) in the alloimmune response. However,…
  • 2013 American Transplant Congress

    Monitoring of Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR) in Patients with Focal Segmental Glomeruloscerosis (FSGS) Undergoing Kidney Transplantation

    F. Halleck, O. Staeck, D. Khadzhynov, M. Duerr, M. Naik, L. Liefeldt, I. Lieker, T. Slowinski, H. Neumayer, K. Budde

    Dpt. of Nephrology, Charité Universitaetsmedizin Campus Mitte, Berlin, Germany

    Background: suPAR was shown to be elevated in approximately 60% of patients (pts) with primary FSGS. Increased levels before transplantation were predictive of FSGS recurrence,…
  • 2013 American Transplant Congress

    Clinical Impact of an ACE Insertion/Deletion and Kinin B2 Receptor +9/-9 Polymorphisms in the Prognosis of Renal Transplantation

    C. Amorim, S. Almeida, P. Gomes, R. Bacurau, N. Camara, R. Araujo

    UNIFESP, Sao Paulo, Brazil; UNIFESP, Sao Paulo, Brazil; USP, Sao Paulo, Brazil

    There is a consensus in the scientific literature that supports the importance of the kallikrein kinin and renin angiotensin systems in renal physiology, but notably…
  • 2013 American Transplant Congress

    Geographic Variation May Explain Disparities in Pediatric Waiting List Times for Hispanic Children

    S. Amaral, J. Hwang, J. Shults, V. Potluri, P. Abt, P. Reese

    Pediatrics, The Children's Hosp of Phila, Philadelphia, PA; Biostatistics and Epidemiology, Univ of Pennsylvania, Philadelphia, PA; Surgery, Univ of Pennsylvania, Philadelphia, PA

    Body: Black and Hispanic children with end-stage renal disesase (ESRD) experience longer waiting times for deceased donor kidney transplantation. However, prior studies have not examined…
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