2013 American Transplant Congress
Pre-Transplant Immediately Early-1-Specific T-Cell Responses Provides Protection for CMV Infection after Kidney Transplantation
Human cytomegalovirus (CMV) infection is still a major complication after kidney transplantation. Although it is well known that cytotoxic CMV-specific CD8+ T cells play a…2013 American Transplant Congress
Prolonged Cardiac Allograft Survival Due to Treg Expansion in Recipient BAFF-Tg Mice
Background: B cell activation factor of the TNF family (BAFF) is considered to function as a proinflammatory cytokine. BAFF is crucial for B cell development…2013 American Transplant Congress
Induction of Donor Specific Hyporesponsiveness in Kidney Transplantation Using Adoptive Transfer of Ex Vivo Induced Tolerogenic Cells
[Background] Anergic T cells generated ex vivo under conditions of co-stimulatory blockade are reported to have tolerogenic effects. According this finding, we have conducted the…2013 American Transplant Congress
Prospective Randomized Trial Aimed To Reduce the Incidence of Cytomegalovirus (CMV) Infection in Kidney Transplant (KT) Recipients, A
Nephrology Division, Hospital do Rim e Hipertensão, São Paulo, Brazil
Introduction: CMV infection has been associated with inferior long-term patient and graft survival. This single center prospective study compares the effect of 3 immunosuppressive regimens…2013 American Transplant Congress
Indoleamine 2, 3-Dioxygenase Inhibition Alters Noncoding RNAs Following Ischemia-Reperfusion Injury of the Kidney
Background: Non-coding RNAs (NCR) arise from the non-protein-coding portion of the genome and include microRNAs, small nucleolar RNAs (snoRNA) and ribosomal RNAs (rRNA). NCR are…2013 American Transplant Congress
Interplay between mTOR and STAT5 Signaling Modulates the Balance between Regulatory and Effective T Cells
West China Hospital, Sichuan University, chengdu, China
Background: Allograft outcome, rejection or tolerance, often depends on the balance between regulatory T cells (Tregs) and effective T cells (Teffs). Rapamycin (Rapa) has been…2013 American Transplant Congress
α-Lipoic Acid Protects the Ischemia Reperfusion Injury in Simultaneous Kidney-Pancreas Transplant Patients
Α-lipoic acid (ALA) is a potent antioxidant. ALA is proposed to mitigate the development of diabetic polyneuropathy by addressing reactive oxygen and nitrogen species. ALA…2013 American Transplant Congress
Sildenafil Enhances Renal Blood Flow but Does Not Protect Against Ischaemia Reperfusion Injury in a Model of Donation after Circulatory Death Kidney Transplantation
IntroductionSildenafil has been used as a pre-conditioning agent to protect against ischaemic kidney injury in a porcine cardio-pulmonary bypass model (Patel NN et al, Ann…2013 American Transplant Congress
Non-Influenza Respiratory Viral Infections in Solid Organ Transplant Patients at Two Midwestern Transplant Centers, 2009-2012
Purpose: Expanded availability of multi-pathogen PCR assays has allowed the detection of common respiratory viruses in clinical specimens. Few studies have investigated the epidemiology and…2013 American Transplant Congress
Acute T-Cell Mediated Rejection with Severe Tubulitis or Mild Intimal Arteritis: Which Histological Lesion Predicts Better Graft Outcome?
Background: Acute T-cell-mediated rejection (TCMR) is divided by Banff classification into tubulo-interstitial rejection and vascular rejection according to the presence of arteritis. Vascular rejection is…
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