ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Acute Diverticulitis Incidence, Management, and Outcomes in Solid Organ Transplant Patients

    P. Martins, A. Almusa, J. Markmann, M. Hertl, N. Elias

    Department of Surgery, Transplant Division, Massachusetts General Hospital, Harvard University, Boston, MA

    BACKGROUND: Transplant patients with acute diverticulitis require more frequently an operation because immunosuppresion can mask initial symptoms, delaying treatment and leading to perforation. Our goal…
  • 2013 American Transplant Congress

    Cardiac Allograft Prolongation by Autologous CD117+ Progenitor Cells Requires CD11b Expression from within the CD117+ Cellular Inoculum

    T. Grazia, R. Plenter, C. Lin, R. Gill, M. Zamora

    Division of Pulmonary and Critical Care Medicine, The University of Colorado, Aurora, CO; Surgery, Colorado Center for Transplantation Care Research and Education (CCTCARE), The University of Colorado, Aurora, CO

    Purpose: Published studies demonstrate significant cardiac allograft prolongation with autologous CD117+ progenitor cell (PC) therapy as well as differential engraftment of the allograft and related…
  • 2013 American Transplant Congress

    Status 1 Liver Candidates Benefit from Full Regional Sharing

    E. Edwards, A. Harper, D. Mulligan, K. Olthoff

    United Network for Organ Sharing, Richmond, VA; Mayo Clinic Hospital, Phoenix, AZ; The Hospital of the University of Pennsylvania, Philadelphia, PA

    Introduction. The OPTN implemented full regional sharing of adult donor livers for all Status 1A and Status 1B liver candidates on December 15, 2010. Prior…
  • 2013 American Transplant Congress

    Epithelial-to-Mesenchymal Transition and Tacrolimus Toxicity in Renal Transplant Recipient

    J. Bloch, F. Glowacki, C. Cauffiez, D. Buob, C. Noel, C. Van Der Hauwaert, M. Hazzan

    Nephrology Department, Hôpital Huriez, Centre Hospitalier Régional et Universitaire, Lille, France; EA4483, Faculté de Médecine, Pôle Recherche, Lille, France; Pathology Department, Centre de Biologie et de Pathologie, Centre Hospitalier Régional et Universitaire, Lille, France

    IntroductionAnticalcineurins long-term use is associated with interstitial fibrosis, partly responsible for chronic graft dysfunction in kidney transplantation. Studies in patients treated with cyclosporine show that…
  • 2013 American Transplant Congress

    Low-Molecular-Weight Heparin Dosing and Monitoring in Solid Organ Transplant Recipients

    M. Moten, A. Gaber, D. Putney, S. Patel

    Pharmacy, Tampa General Hospital, Tampa, FL; Surgery, The Methodist Hospital, Houston, TX; Pharmacy, The Methodist Hospital, Houston, TX; Pharmacy, The Methodist Hospital, Houston, TX

    Anti-Xa monitoring for low-molecular-weight heparin (LMWH) is currently recommended in obese, renally impaired, and pregnant patients. Substantial evidence indicates solid organ transplant (SOT) patients are…
  • 2013 American Transplant Congress

    Olmesartan, Angiotensin II Type 1 Receptor Blocker, Induced Prolonged Survival of Murine Cardiac Allografts and Generated Regulatory Cells

    N. Shirasugi, Q. Zhang, D. Iwami, M. Niimi

    Surgery, Teikyo University, Tokyo, Japan; Surgery, Aisei Hospital, Tokyo, Japan

    Background: Several studies have shown that angiotensin II type 1 receptor (AT1 receptor) blockade reduced graft arteriosclerosis and immune-mediated graft damages. Here, we investigated the…
  • 2013 American Transplant Congress

    Liver Biopsy as Rejection Criteria in Living Donor Liver Transplant: Analysis of 94 Cases

    W. Al-hamoudi, F. Abaalkhail, H. Almanea, H. Elsiesy, A. Hashim, M. Al-sofayan, H. Albahili, D. Broering, M. Al sebayel

    King Saud University, Riyadh, Saudi Arabia; Liver Transplantatiom, King Faisal Specialist Hospital, Riyadh, Saudi Arabia

    Background: The application of liver biopsy as one of the selection criteria in living donor liver transplantation (LDLT) is controversial. In populations with high prevalence…
  • 2013 American Transplant Congress

    Evidence That Anti-Interleukin-6 Receptor Treatment Modulates Splenic T-Cell Subsets during Development of Allosensitization

    I. Kim, G. Wu, N. Chai, S. Jordan, A. Klein

    Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA

    Introduction: We previously reported that inhibition of IL-6/IL-6R interactions by an anti-IL6R monoclonal (mMR16-1) attenuates anti-HLA-A2 responses in a mouse model of sensitization. The current…
  • 2013 American Transplant Congress

    Simple Post-Transplant Immunological Score Accurately Predicts the Risk of Infection in Kidney Transplant (KT) Recipients, A

    M. Fernández-Ruiz, F. López-Medrano, L. Allende, P. Varela, R. San Juan, C. Lumbreras, A. Andrés, N. Polanco, J. Morales, E. Paz-Artal, J. Aguado

    Unit of Infectious Diseases, Hospital Universitario "12 de Octubre", Madrid, Spain; Department of Immunology, Hospital Universitario "12 de Octubre", Madrid, Spain; Department of Nephrology, Hospital Universitario "12 de Octubre", Madrid, Spain

    Aim: To develop a practical score –based on readily available immunological parameters– to predict the risk of infection in KT recipients.Methods: We included 245 patients…
  • 2013 American Transplant Congress

    Baicalin Mediates Renal IRI Protection through Inhibition of NF-κB Pathway and Mitochondria Mediated Apoptosis

    M. Lin, L. Li, G. Pokhrel, G. Qi, J. Wang, L. Li, M. Xu, R. Rong, T. Zhu

    Urology, Zhongshan Hospital, Fudan University, Shanghai, China; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China

    Background: Renal ischemia reperfusion injury (IRI) would highly increase the risk of delayed graft function (DGF) and rejection, and subsequently decrease the long-term graft survival…
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