ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Size Does Matter: A Comparison of CT-Measured Donor Kidney Cortex Volume to Radioisotopic GFR Measurement in Living Kidney Donation

    F. Halleck, G. Diederich, F. Engelken, T. Manning, F. Friedersdorff, F. Fuller, A. Magheli, H. Neumayer, K. Budde, J. Waiser

    Nephrology, Charité Berlin Campus Mitte, Berlin, Germany; Radiology, Charité Berlin Campus Mitte, Berlin, Germany; Urology, Charité Berlin Campus Mitte, Berlin, Germany

    Living kidney donation (LKD) needs a careful evaluation of the kidney function of the donor. There are diverging evaluation methods in use. The purpose of…
  • 2013 American Transplant Congress

    Germinal Centre Responses Drive Epitope Diversification in an Autoantibody-Mediated Model of Heart Allograft Vasculopathy

    M. Qureshi, T. Conlon, R. Motallebzadeh, I. Harper, E. Bolton, J. Bradley, G. Pettigrew

    Surgery, University of Cambridge, Cambridge, United Kingdom

    IntroductionAutoantibody following organ transplantation is increasingly correlated with poor graft outcome.We have reported recently that in a MHC class II mismatched mouse heart transplant model,graft-versus-host…
  • 2013 American Transplant Congress

    Boceprevir-Based Tritherapy of HCV-Infected Belgian Liver Transplanted Patients: Preliminary Experience

    D. Degré, I. Colle, H. Van Vlierberghe, C. Moreno

    Department of Gastroenterology Hepatopancreatology and Digestive Oncology, Erasme Hospital Université Libre de Bruxelles, Brussels, Belgium; Department of Hepatogastroenterology, Ghent University Hospital, Ghent, Belgium

    Background: Management of recurrent hepatitis C infection remains a major challenge after liver transplantation. Protease-inhibitor based regimens improve virological response in non-transplanted HCV genotype 1…
  • 2013 American Transplant Congress

    Olmesartan, Angiotensin II Type 1 Receptor Blocker, Induced Prolonged Survival of Murine Cardiac Allografts and Generated Regulatory Cells

    N. Shirasugi, Q. Zhang, D. Iwami, M. Niimi

    Surgery, Teikyo University, Tokyo, Japan; Surgery, Aisei Hospital, Tokyo, Japan

    Background: Several studies have shown that angiotensin II type 1 receptor (AT1 receptor) blockade reduced graft arteriosclerosis and immune-mediated graft damages. Here, we investigated the…
  • 2013 American Transplant Congress

    Liver Biopsy as Rejection Criteria in Living Donor Liver Transplant: Analysis of 94 Cases

    W. Al-hamoudi, F. Abaalkhail, H. Almanea, H. Elsiesy, A. Hashim, M. Al-sofayan, H. Albahili, D. Broering, M. Al sebayel

    King Saud University, Riyadh, Saudi Arabia; Liver Transplantatiom, King Faisal Specialist Hospital, Riyadh, Saudi Arabia

    Background: The application of liver biopsy as one of the selection criteria in living donor liver transplantation (LDLT) is controversial. In populations with high prevalence…
  • 2013 American Transplant Congress

    Evidence That Anti-Interleukin-6 Receptor Treatment Modulates Splenic T-Cell Subsets during Development of Allosensitization

    I. Kim, G. Wu, N. Chai, S. Jordan, A. Klein

    Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA

    Introduction: We previously reported that inhibition of IL-6/IL-6R interactions by an anti-IL6R monoclonal (mMR16-1) attenuates anti-HLA-A2 responses in a mouse model of sensitization. The current…
  • 2013 American Transplant Congress

    Simple Post-Transplant Immunological Score Accurately Predicts the Risk of Infection in Kidney Transplant (KT) Recipients, A

    M. Fernández-Ruiz, F. López-Medrano, L. Allende, P. Varela, R. San Juan, C. Lumbreras, A. Andrés, N. Polanco, J. Morales, E. Paz-Artal, J. Aguado

    Unit of Infectious Diseases, Hospital Universitario "12 de Octubre", Madrid, Spain; Department of Immunology, Hospital Universitario "12 de Octubre", Madrid, Spain; Department of Nephrology, Hospital Universitario "12 de Octubre", Madrid, Spain

    Aim: To develop a practical score –based on readily available immunological parameters– to predict the risk of infection in KT recipients.Methods: We included 245 patients…
  • 2013 American Transplant Congress

    Baicalin Mediates Renal IRI Protection through Inhibition of NF-κB Pathway and Mitochondria Mediated Apoptosis

    M. Lin, L. Li, G. Pokhrel, G. Qi, J. Wang, L. Li, M. Xu, R. Rong, T. Zhu

    Urology, Zhongshan Hospital, Fudan University, Shanghai, China; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China

    Background: Renal ischemia reperfusion injury (IRI) would highly increase the risk of delayed graft function (DGF) and rejection, and subsequently decrease the long-term graft survival…
  • 2013 American Transplant Congress

    Perfluorocarbon Added to the University of Winsconsin Solution Reduces Ischemia Reperfusion Injury and Prolongs Survival of DCD Liver Grafts

    P. Martins, T. Berendsen, H. Yeh, B. Bruinsma, M. Izamis, K. Uygun, J. McDaid, M. Yarmush, J. Markmann

    Dept. of Surgery, Division of Transplantation, Massachusetts General Hospital, Boston, MA; Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, and the Shriners Hospitals for Children, Boston, MA

    Background: Low ATP contents in the graft have been associated with poor transplant outcomes. DCD grafts are particularly vulnerable to ischemia reperfusion injury because of…
  • 2013 American Transplant Congress

    Gender Difference in Renal Ischemia Tolerance Is Extrinsic to the Kidney

    M. Levine, Z. Wang, Y. Wang, R. Redfield, P. Abt, L. Wang, W. Hancock

    Surgery, Transplant Division, University of Pennsylvania, Philadelphia, PA; Pathology, Children's Hospital of Philadelphia, Philadelphia, PA

    Background: Gender has been shown to have some impact on tolerance of ischemia-reperfusion injury (IRI) in animal models, with female mice having greater IRI tolerance.…
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