2013 American Transplant Congress
Rituximab To Prevent Renal Allograft Rejection; a Randomized, Double-Blind, Placebo-Controlled Trial
BackgroundAnti-B-cell therapy could reduce the incidence of acute renal allograft rejection, especially in immunized patients. This study evaluated the efficacy and safety of rituximab added…2013 American Transplant Congress
Thymoglobulin (rATG) Induction Improves Survival in Heart Transplant Recipients: A Retrospective Single-Center Study
A: Our study is a retrospective analysis of heart transplant recipients transplanted in 2009 and were induced with rATG vs. no induction. We hypothesized that…2013 American Transplant Congress
Somah – A Novel Modality for Subnormothermic Preservation of Donor Hearts
Background- Donor hearts for transplant are stored in extreme hypothermic conditions to reduce ischemic damage. However, hypothermia-dependent cellular, biochemical, structural injuries are of concern. We…2013 American Transplant Congress
Clinical Impact and Evolution of Humoral Immunity in a Randomized Multicenter Trial of Steroid Avoidance in Pediatric Renal Transplantation, The
PURPOSE: The development of anti-donor humoral responses after transplantation associates with higher risks for acute rejection and 1-year graft survival in adults, but the influence…2013 American Transplant Congress
Strain Specific Induction of Regulatory T Cells by Plasmacytoid Dendritic Cells
Life sustaining, full MHC-mismatched mouse kidney transplants are spontaneously accepted in certain strain combinations (e.g., DBA/2 to B6), while some full MHC-mismatched mouse kidneys are…2013 American Transplant Congress
Belatacept Post-Approval Implementation: A Large Single Center Experience
Emory Transplant Center, Atlanta, GA; Bristol-Myers Squibb, Princeton, NJ
Belatacept is a novel CD28 pathway antagonist that was recently approved as a maintenance immunosuppressive agent for kidney transplant recipients. While the pivotal trials for…2013 American Transplant Congress
Time in the Operating Room Independently Predicts Blood Utilization, Charges, and a Cost Efficient Practice
Center for Transplantation, University of Kansas Medical Center, Kansas City, KS
BACKGROUND: In an era of economic reform we see clinical practice under increasing performance oversight. To date few studies that have looked specifically at clinical…2013 American Transplant Congress
Comparison of Histamine Receptor Antagonists Versus Proton Pump Inhibitor Stress Ulcer Prophylaxis in Kidney Transplant Recipients, A
Purpose: Histamine-2 receptor antagonists (H2RA) or proton pump inhibitors (PPI) are often utilized for stress ulcer prophylaxis in kidney transplant (KTx) recipients. The purpose of…2013 American Transplant Congress
IL21 Plays a Critical Role in Chronic Rejection but Not in Acute or Accelerated Allograft Rejection
University of Toledo College of Medicine, Toledo
There is mounting evidence that IL21 may be a specialized cytokine that controls chronic rather than acute immune responses. Herein, we evaluated the role of…2013 American Transplant Congress
Monocyte FcγRIIa Allotype Influences Recruitment to Endothelial Cells Triggered by HLA I Antibodies
Pathology and Laboratory Medicine, UCLA, Los Angeles, CA
Background: HLA I antibody (Ab) activation of endothelial cells (EC) promotes monocyte recruitment through P-selectin and FcΓRI and FcΓRIIa. Human FcΓRIIa is dimorphic. R131 allele…