ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Belatacept Post-Approval Implementation: A Large Single Center Experience

    A. Adams, C. Garrett, A. Chami, M. Harler, S. Pastan, A. Kirk, T. Pearson, C. Larsen

    Emory Transplant Center, Atlanta, GA; Bristol-Myers Squibb, Princeton, NJ

    Belatacept is a novel CD28 pathway antagonist that was recently approved as a maintenance immunosuppressive agent for kidney transplant recipients. While the pivotal trials for…
  • 2013 American Transplant Congress

    Normative Values for Transplant Health-Related Quality of Life

    D. Radosevich, L. McHugh, H. Doan, R. Bailey, G. Cordner, L. Kathryn, M. Hertz, A. Matas, J. Lake, R. Kandaswamy, M. Colvin-Adams, T. Pruett

    Department of Surgery, University of Minnesota, Minneapolis, MN; Center for Lung Science and Health Medical Director, University of Minnesota, Minneapolis, MN; Department of Medicine, Cardiovascular Division, University of Minnesota, Minneapolis, MN; Transplant Information Services, Fairview Health Services, Minneapolis, MN

    Background. Health-related quality of life (HRQoL) evaluates health from the view point of the individual and preferences the “quality of live versus the quantity of…
  • 2013 American Transplant Congress

    False Hepatitis C Antibody Development in Left Ventricular Assist Device Recipients Who Proceed to Heart Transplantation

    D. Lee, D. Levy, J. Shuter, G. Minamoto, D. Goldstein, D. D'Alessandro, V. Muggia

    Medicine, Division of Infectious Disease, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY; Cardiovascular and Thoracic Surgery, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY

    Purpose: Ventricular assist devices (VAD) have been shown to lead to immune activation and higher frequencies of autoantibodies. Previous research reports a rate of 30%…
  • 2013 American Transplant Congress

    Altered Serum miR-326 and miR-142-3p Profiles during Acute Rejection after Heart Transplantation

    I. Dewi, K. Torngren, O. Gidlöf, B. Kornhall, J. Öhman

    Department of Cardiology, Lund University, Lund, Sweden; Clinic of Heart Failure and Valvular Disease, Skåne University Hospital, Lund, Sweden

    IntroductionCirculating miRNAs may serve the purpose as practicable non-invasive biological marker of allograft status in heart transplanted patients, as they can be detected in serum…
  • 2013 American Transplant Congress

    Rituximab To Prevent Renal Allograft Rejection; a Randomized, Double-Blind, Placebo-Controlled Trial

    M. van den Hoogen, E. Steenbergen, A. Hoitsma, L. Hilbrands

    Nephrology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands; Pathology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands

    BackgroundAnti-B-cell therapy could reduce the incidence of acute renal allograft rejection, especially in immunized patients. This study evaluated the efficacy and safety of rituximab added…
  • 2013 American Transplant Congress

    Thymoglobulin (rATG) Induction Improves Survival in Heart Transplant Recipients: A Retrospective Single-Center Study

    T. Jarmi, A. Naif, M. Weston

    College of Pharmacy, University of South Florida, Tampa, FL; Internal Medicine, University of South Florida, Tampa, FL; Tampa General Hospital, Tampa, FL

    A: Our study is a retrospective analysis of heart transplant recipients transplanted in 2009 and were induced with rATG vs. no induction. We hypothesized that…
  • 2013 American Transplant Congress

    Time in the Operating Room Independently Predicts Blood Utilization, Charges, and a Cost Efficient Practice

    R. Gilroy, S. Kumer, J. Kindscher, T. Giacoma, E. Charlton, W. Dunn, T. Schmitt

    Center for Transplantation, University of Kansas Medical Center, Kansas City, KS

    BACKGROUND: In an era of economic reform we see clinical practice under increasing performance oversight. To date few studies that have looked specifically at clinical…
  • 2013 American Transplant Congress

    Comparison of Histamine Receptor Antagonists Versus Proton Pump Inhibitor Stress Ulcer Prophylaxis in Kidney Transplant Recipients, A

    G. Morris, K. Hardinger, D. Tsapepas, E. Tichy

    Department of Pharmacy, Yale-New Haven Hospital, New Haven, CT; Department of Pharmacy, Columbia University Medical Center, New York, NY; School of Pharmacy, University of Missouri- Kansas City, Kansas City, MO

    Purpose: Histamine-2 receptor antagonists (H2RA) or proton pump inhibitors (PPI) are often utilized for stress ulcer prophylaxis in kidney transplant (KTx) recipients. The purpose of…
  • 2013 American Transplant Congress

    IL21 Plays a Critical Role in Chronic Rejection but Not in Acute or Accelerated Allograft Rejection

    P. Schroder, M. Khattar, C. Baum, W. Chen, S. Stepkowski

    University of Toledo College of Medicine, Toledo

    There is mounting evidence that IL21 may be a specialized cytokine that controls chronic rather than acute immune responses. Herein, we evaluated the role of…
  • 2013 American Transplant Congress

    Monocyte FcγRIIa Allotype Influences Recruitment to Endothelial Cells Triggered by HLA I Antibodies

    N. Valenzuela, E. Reed

    Pathology and Laboratory Medicine, UCLA, Los Angeles, CA

    Background: HLA I antibody (Ab) activation of endothelial cells (EC) promotes monocyte recruitment through P-selectin and FcΓRI and FcΓRIIa. Human FcΓRIIa is dimorphic. R131 allele…
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