ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Rituximab To Prevent Renal Allograft Rejection; a Randomized, Double-Blind, Placebo-Controlled Trial

    M. van den Hoogen, E. Steenbergen, A. Hoitsma, L. Hilbrands

    Nephrology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands; Pathology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands

    BackgroundAnti-B-cell therapy could reduce the incidence of acute renal allograft rejection, especially in immunized patients. This study evaluated the efficacy and safety of rituximab added…
  • 2013 American Transplant Congress

    Thymoglobulin (rATG) Induction Improves Survival in Heart Transplant Recipients: A Retrospective Single-Center Study

    T. Jarmi, A. Naif, M. Weston

    College of Pharmacy, University of South Florida, Tampa, FL; Internal Medicine, University of South Florida, Tampa, FL; Tampa General Hospital, Tampa, FL

    A: Our study is a retrospective analysis of heart transplant recipients transplanted in 2009 and were induced with rATG vs. no induction. We hypothesized that…
  • 2013 American Transplant Congress

    Somah – A Novel Modality for Subnormothermic Preservation of Donor Hearts

    S. Lowalekar, H. Cao, X. Lu, P. Treanor, H. Thatte

    Cardiac Surgery Division, VA Boston Healthcare System, Boston, MA; Surgery, Brigham and Women's Hospital, Boston, MA; Surgery, Harvard Medical School, Boston, MA

    Background- Donor hearts for transplant are stored in extreme hypothermic conditions to reduce ischemic damage. However, hypothermia-dependent cellular, biochemical, structural injuries are of concern. We…
  • 2013 American Transplant Congress

    Clinical Impact and Evolution of Humoral Immunity in a Randomized Multicenter Trial of Steroid Avoidance in Pediatric Renal Transplantation, The

    M. Sarwal, A. Chadhuri, M. Ozawa, M. Everly, R. Ettenger, V. Dharnidharka, M. Benfield, R. Mathias, A. Portale, R. McDonald, W. Harmon, D. Kershaw, V. Vehaskari, E. Kamil, H. Baluarte, B. Warady, T. Sigdel, H. Szu-chuan, H. Dai, M. Naesens, J. Waskerwitz, O. Salvatierra, P. Terasaki

    California Pacific Medical Center, San Francisco, CA; One Lambda, LA; For the Multicenter SNSO1 study, , CA

    PURPOSE: The development of anti-donor humoral responses after transplantation associates with higher risks for acute rejection and 1-year graft survival in adults, but the influence…
  • 2013 American Transplant Congress

    Strain Specific Induction of Regulatory T Cells by Plasmacytoid Dendritic Cells

    D. Ndishabandi, K. Shinoda, R. Colvin, A. Alessandrini

    Surgery, Massachusetts General Hospital, Boston; Pathology, Massachusetts General Hospital, Boston, MA

    Life sustaining, full MHC-mismatched mouse kidney transplants are spontaneously accepted in certain strain combinations (e.g., DBA/2 to B6), while some full MHC-mismatched mouse kidneys are…
  • 2013 American Transplant Congress

    Belatacept Post-Approval Implementation: A Large Single Center Experience

    A. Adams, C. Garrett, A. Chami, M. Harler, S. Pastan, A. Kirk, T. Pearson, C. Larsen

    Emory Transplant Center, Atlanta, GA; Bristol-Myers Squibb, Princeton, NJ

    Belatacept is a novel CD28 pathway antagonist that was recently approved as a maintenance immunosuppressive agent for kidney transplant recipients. While the pivotal trials for…
  • 2013 American Transplant Congress

    Time in the Operating Room Independently Predicts Blood Utilization, Charges, and a Cost Efficient Practice

    R. Gilroy, S. Kumer, J. Kindscher, T. Giacoma, E. Charlton, W. Dunn, T. Schmitt

    Center for Transplantation, University of Kansas Medical Center, Kansas City, KS

    BACKGROUND: In an era of economic reform we see clinical practice under increasing performance oversight. To date few studies that have looked specifically at clinical…
  • 2013 American Transplant Congress

    Comparison of Histamine Receptor Antagonists Versus Proton Pump Inhibitor Stress Ulcer Prophylaxis in Kidney Transplant Recipients, A

    G. Morris, K. Hardinger, D. Tsapepas, E. Tichy

    Department of Pharmacy, Yale-New Haven Hospital, New Haven, CT; Department of Pharmacy, Columbia University Medical Center, New York, NY; School of Pharmacy, University of Missouri- Kansas City, Kansas City, MO

    Purpose: Histamine-2 receptor antagonists (H2RA) or proton pump inhibitors (PPI) are often utilized for stress ulcer prophylaxis in kidney transplant (KTx) recipients. The purpose of…
  • 2013 American Transplant Congress

    IL21 Plays a Critical Role in Chronic Rejection but Not in Acute or Accelerated Allograft Rejection

    P. Schroder, M. Khattar, C. Baum, W. Chen, S. Stepkowski

    University of Toledo College of Medicine, Toledo

    There is mounting evidence that IL21 may be a specialized cytokine that controls chronic rather than acute immune responses. Herein, we evaluated the role of…
  • 2013 American Transplant Congress

    Monocyte FcγRIIa Allotype Influences Recruitment to Endothelial Cells Triggered by HLA I Antibodies

    N. Valenzuela, E. Reed

    Pathology and Laboratory Medicine, UCLA, Los Angeles, CA

    Background: HLA I antibody (Ab) activation of endothelial cells (EC) promotes monocyte recruitment through P-selectin and FcΓRI and FcΓRIIa. Human FcΓRIIa is dimorphic. R131 allele…
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