Am J Transplant, Volume 3, Suppl 5 Archives - Page 17 of 178 - ATC Abstracts

2013 American Transplant Congress
Transplant Certification and Quality Assessment: The Effect of Center Data Input Quality
J. Tuttle-Newhall, K. Lentine, D. Axelrod, L. Ware, J. Milton, M. Schnitzler
Center for Abdominal Transplantation, Saint Louis University, St. Louis; Dartmouth College, Lebanon; University of Texas, San Antonio
Each transplant program in the United States is required to submit self-reported data to OPTN/UNOS to calculate a center’s performance. Currently, under the Conditions of…
2013 American Transplant Congress
Successful Ex-Vivo Normothermic Machine Perfusion and Viability Testing of Discarded Human Donor Livers
S. op den Dries, N. Karimian, M. Sutton, A. Westerkamp, M. Nijsten, A. Gouw, J. Wiersema-Buist, T. Lisman, H. Leuvenink, R. Porte
Section of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, University Medical Center Groningen, Groningen, Netherlands; Surgical Research Laboratory, Department of Surgery, University Medical Center Groningen, Groningen, Netherlands; Department of Critical Care, University Medical Center Groningen, Groningen, Netherlands; Department of Pathology, University Medical Center Groningen, Groningen, Netherlands
In contrast to traditional static cold preservation of donor livers, normothermic machine perfusion may reduce preservation injury, improve graft viability, and potentially allows ex-vivo assessment…
2013 American Transplant Congress
Neutralization of IL-23 Is Protective Against Hepatic Cold Ischemia/Reperfusion (I/R) Injury
J. Klune, S. Yokota, C. Bartels, N. Murase, Q. Du, D. Geller
Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA
Purpose: Interleukin-23 (IL-23) can activate inflammatory pathways such as CD4+ cell differentiation into IL-17 secreting Th17 cell type and increased production of IFNg leading to…
2013 American Transplant Congress
Pulmonary Hypertension Identified by Color Doppler Echocardiography in Renal Transplant Candidates: Prevalence and Effect on Survival
A. Ribeiro, M. Gazzana, A. Vicari, M. Knorst, R. Manfro
Nephrology Department, Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil; Pulmonology Departament, Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil
Background: Pulmonary hypertension (PH) has been recognized frequently in patients with chronic renal failure undergoing hemodialysis. Some studies have suggested that PH may be associated…
2013 American Transplant Congress
Risk Factors, Rejection and Infections Associated with Neutropenia in Solid Organ Transplantation: A Retrospective Study
S. Clairoux, M. Fournier, J. Amiel, M. Tremblay, D. Vinh, C. Coursol, D. Thirion, M. Cantarovich
Department of Pharmacy, McGill University Health Center (MUHC), Montreal, Canada; Faculty of Pharmacy, University of Montreal, Montreal, Canada; Multi-Organ Transplant Program, MUHC, Montreal, Canada; Division of Infectious Diseases, MUHC, Montreal, Canada
Introduction: Neutropenia is relatively frequent after solid organ transplantation (SOT). Its risk factors have been scarcely studied and its consequences remain to be defined in…
2013 American Transplant Congress
Jak3 Dependent Inhibition of Alloreactive T Cell Proliferation in the Setting of Chronic TLR Stimulation
T. Brennan, L. Lin, Y. Yang
Surgery, Duke University, Durham, NC; Medicine and Immunology, Duke University, Durham, NC
Background: Maturation of dendritic cells (DCs) by a pulse TLR ligands increases their antigen presentation efficacy and leads to increased proliferation of T cells in…
2013 American Transplant Congress
Common Rejection Module (CRM) across Multiple Transplant Organs Identifies Novel Therapeutics for Treatment of Acute Rejection in Solid Organ Transplantation, A
S. Roedder, P. Khatri, N. Kimura, K. De Vusser, A. Morgan, Y. Gong, M. Fischbein, R. Robbins, M. Naesens, A. Butte, M. Sarwal
Transplantation Research BIOMARC Program, California Pacific Medical Center, Sutter Health, San Francisco, CA; Pediatrics, Division of Systems Medicine, Stanford University, Stanford, CA; Cardiothoracic Surgery, Stanford University, Stanford, CA; Nephrology, Leuven University, Leuven, Belgium
We performed meta-analyses of eight datasets comprising whole genome microarray expression profiles on 236 graft biopsy samples from four types of transplanted organs (kidney, lung,…
2013 American Transplant Congress
Cardiovascular Disease and Kidney Disease Progression in Kidney Transplant Recipients
A. John, D. Weiner, M. Carpenter, L. Hunsicker, J. Kusek, M. Pfeffer, S. Solomon, M. Weir, A. Levey
Tufts Medical Center, Boston, MA; University of North Carolina, Chapel Hill, NC; University of Iowa, Iowa City, IA; University of Maryland, Baltimore, MD; Brigham and Women's Hospital, Boston, MA; National Institute of Health, Bethesda, MD
Background: Kidney transplant recipients have a high prevalence of cardiovascular disease (CVD) and CVD risk factors, such that CVD is the leading cause of mortality.…
2013 American Transplant Congress
For Cause Renal Biopsies Are Heterogeneous Irrespective of Clinical Presentation
A. Cherukuri, S. Balasubramanian, P. Prasad, C. Angel, A. Lewington, C. Newstead, B. Clark, R. Baker
St.James's University Hospital, Leeds, United Kingdom
Deteriorating renal function either evidenced by a rise in serum creatinine or proteinuria remains the most important indication for a late transplant biopsy. Over the…
2013 American Transplant Congress
Standardized Referral Ratio (SRR): A New Quality Measure, The
R. Patzer, S. Pastan
Emory Transplant Center, Atlanta; Department of Epidemiology, Rollins School of Public Health, Atlanta; Department of Medicine, Renal Division, Emory University, Atlanta
Purpose: Variability in dialysis facility-level kidney transplant (KTx) rates have been reported, but little is known about KTx referral rates by dialysis facilities. No studies…