ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Mesenchymal Stem Cells Suppress Cytotoxic Activity of Natural Killer Cells in Islet Cell Transplantation

    Y. Saeki, K. Ishiyama, F. Hirata, Y. Tanaka, H. Ohdan

    Hiroshima University, Hiroshima, Japan

    Introduction:The immune response occurs against islet graft immediately after islet transplantation has remained a major obstacle. We have shown that both the expression of TNF-related…
  • 2013 American Transplant Congress

    Modulating T Cell Migration in the Postischemic Liver: Hepatic Stellate Cells as New Therapeutic Target?

    A. Khandoga, K. Mende, M. Rentsch, J. Reifart

    Department of Surgery-Grosshadern, University of Munich, Munich, Germany

    Background: CD4+ T cells play a critical role during hepatic ischemia-reperfusion (I/R) injury although the mechanisms of their migration in the postischemic liver in remain…
  • 2013 American Transplant Congress

    Matrix Cellular Activation of Non-Phagocytic SIRP-α Stimulates NADPH-Oxidase To Promote Cell Death, Limit Blood Flow and Promote Renal Ischemia Reperfusion Injury

    N. Rogers, M. Yao, G. Csanyi, A. Rodrigues, P. Pagano, A. Thomson, J. Isenberg

    Department of Medicine, University of Pittsburgh, Pittsburgh, PA; Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA

    Ischemia reperfusion injury (IRI) remains a source of organ transplant injury and accelerant of graft rejection. Current interventions to mitigate IRI and promote tissue preservation…
  • 2013 American Transplant Congress

    B-Cell-Attracting Chemokine-13 (CXCL13) in Human and Murine Kidney Allograft Rejection

    L. Schiffer, F. Wiehler, R. Song, S. von Vietinghoff, M. Schiffer, W. Gwinner, M. Daemmrich, H. Haller, F. Gueler

    Medicine/Nephrology, Hannover Medical School, Hannover, Germany; Pathology, Hannover Medical School, Hannover, Germany

    Purpose: B-cells play an important role in acute renal allograft rejection. It is known that the B-cell-attracting chemokine 13 (CXCL13), which is expressed by dendritic…
  • 2013 American Transplant Congress

    Autophagy-Deficient T Cells Are Resistant to Cell Death after Costimulatory Blockade

    D. Verghese, K. Zhang, B. Murphy, B. Schroppel

    Nephrology, Mount Sinai School of Medicine, New York, NY

    The induction and maintenance of stable transplant tolerance involves both regulatory and deletional mechanisms, the latter of which have been attributed to T cell apoptosis.…
  • 2013 American Transplant Congress

    Search for New Nephroprotective Strategies in Orthotopic Liver Transplantation

    A. Minou, A. Kalachyk, A. Dzyadzko, A. Scherba, O. Rummo, P. Harden

    National Center of Organ Transplantation, Minsk, Belarus; Kidney Unit, Oxford Transplant Center and Kidney Unit, Oxford, United Kingdom

    The classical OLT technique (>90% of cases in our centre) leads to increased rates of acute kidney injury (AKI up to 81, 4%). The purpose…
  • 2013 American Transplant Congress

    Human Microbiota Characterization in the Course of Renal Transplantation

    J. Bromberg, W. Fricke

    Surgery, University of Maryland, Baltimore, MD; Institute for Genome Sciences, University of Maryland, Baltimore, MD

    BACKGROUND: The human microbiota comprises all microbes associated with the human body and could play an important role for transplant recipient health. It may serve…
  • 2013 American Transplant Congress

    Public Survey of Acceptable Financial Incentives for Living Donation: Challenging Assumptions and Reinvigorating the Debate, A

    C. Patel, M. Sohn, B. Hippen, L. Sherman, E. Gordon

    Northwestern University, Chicago; Case Western Reserve University, Cleveland; Carolinas Medical Center, Charlotte

    Background. The potential use of financial incentives to increase living kidney donation rates has generated much controversy over the potential for exploitation of and undue…
  • 2013 American Transplant Congress

    Assessment of Preventable and Non-Preventable Early Rehospitalization Following Kidney Transplantation

    M. Nair, E. Lin, A. Pai, M. Harhay, A. Huverserian, A. Mussell, A. Troxel, M. Levine, J. Shea, P. Abt, R. Bloom, P. Reese

    University of Pennsylvania, Philadelphia, PA

    Early rehospitalization following transplant surgery occurs in 28.5% of kidney transplant (KT) recipients, compared to rates of 10-16% following other abdominal surgeries. Studies of claims…
  • 2013 American Transplant Congress

    Influence of Recipient Age on Outcomes in Paired Kidney Transplantation

    U. Farooq, Y. Al-Shraideh, G. Orlando, J. Rogers, A. Farney, R. Stratta

    Abdominal Transplant, General Surgery, Wake Forest Baptist Medical Center, Winston Salem, NC

    We compared the effect of older recipient age (70 vs <70 yrs) on kidney transplant (KT) outcomes in adult patients (pts) receiving mate kidneys from…
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