2013 American Transplant Congress
Different Sensitivities of Blood Group A and B Antigen-Responsive B Cells to Calcineurin Inhibitors
Hiroshima University, Hiroshima, Japan
[Aim]We have previously demonstrated that B cells recognizing blood group A antigens belong to CD11b+CD5+B-1a cells, and treatment with calcineurin inhibitors(CNIs), which blocks B-1a cell…2013 American Transplant Congress
Development of a Clinically Relevant Conditioning Regimen Using Available Costimulatory Blockade Reagents for Induction of Renal Allograft Tolerance Via Mixed Hematopoietic Chimerism
Transplant Center, Massachusetts General Hospital, Boston, MA
Background: We have previously reported that costimulation blockade (CB) with anti-CD154 mAb (mAb154) promotes mixed chimerism and renal allograft tolerance in nonhuman primates. However, this…2013 American Transplant Congress
Trends in Usage and Outcomes for Expanded Criteria Donor Kidney Transplantation
Duke University Medical Center, Durham, NC; Clinical Trials and Consulting Services, Cincinnati, OH
Expanded criteria donor (ECD) kidneys have been incorporated into the donor pool over the past decade to combat organ shortages. We sought to analyze the…2013 American Transplant Congress
Renal Graft Survival among Primary, Re-Transplant, and Kidney after Solid Organ Transplantation: A Single Center Experience
University of Pittsburgh, Pittsburgh
Introduction: With improved patient outcomes after renal transplants, repeat renal and kidney after solid organs are increasingly being done. Because of paucity of outcomes data…2013 American Transplant Congress
Prevalence and Outcomes of Pulmonary Embolism in Patients with Kidney Transplant
Nephrology and Hypertension, Cleveland Clinic, Cleveland, OH
Prevalence and Outcomes of Pulmonary Embolism in Patients with Kidney TransplantAnkit Sakhuja MD, Jesse D Schold PhD, Diana Deitzer DO, Brian Stephany MDIntroduction: This study…2013 American Transplant Congress
Opting Out: Confidentiality & Alibis for Living Kidney Donors
Yale-New Haven Hospital Transplant Center, New Haven, CT; Yale School of Medicine, New Haven, CT
BackgroundAn individual who withdraws from evaluation as a candidate living kidney donor (CD) may be uncomfortable informing the intended recipient (IR). To protect CD autonomy…2013 American Transplant Congress
Blocking CD47-SIRPα Signaling Promotes the Phagocytic Activity of Macrophages Against Hepatocellular Carcinoma
Department of Transplantation Surgery, Hiroshima University Hospital, Hiroshima, Japan
Background: We have previously demonstrated that immunotherapy with donor derived Natural Killer (NK) cells has a potential for preventing HCC recurrence in living LT patients…2013 American Transplant Congress
Increasing the Accuracy of Mycophenolic Acid Exposure Estimation in Heart Transplants Using 3 Predictive Tools
Purpose: Mycophenolic acid (MPA) area under the curve (AUC) has been reported as an important marker of graft outcome. Pharmacokinetic (PK) tools for the MPA…2013 American Transplant Congress
Shared Decision Making in Organ Transplantation
Background: Shared Decision Making (SDM) is a model of patient-provider communication stressing communication and joint participation in healthcare decisions to provide mutually agreed upon treatment.…2013 American Transplant Congress
Modification of Donor Tissue Antigens with Papain To Inhibit Transplant Rejection
Immunobiology Laboratory, Massachusetts General Hospital & Harvard Medical, Charlestown, MA
PURPOSE: The development of novel drugs to hinder transplant rejection is expensive, time consuming and inevitably exposes the subject to lifelong immunosuppression. In contrast, modifying…
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