ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Conversion from TAC-MMF to mTOR-TAC Immunosuppression in Kidney-Pancreas Transplantation Reduces the Incidence of BK Viremia

    R. Knight, S. Patel, J. DeVos, L. Moore, A. Gaber

    Surgery, The Methodist Hospital, Houston, TX; Pharmacy, The Methodist Hospital, Houston, TX

    Background: BK nephropathy is an important cause of early graft loss after renal-pancreas transplantation. We sought to determine if conversion from tacrolimus/mycophenolate mofetil (TAC-MMF) to…
  • 2013 American Transplant Congress

    Calcineurin Inhibitors in HLA Identical Living Related Donor Kidney Transplantation

    P. Verghese, T. Dunn, S. Chinnakotla, K. Gillingham, A. Matas, M. Mauer

    University of Minnesota, Minneapolis

    The outcome of living related (LD) HLA-identical kidney transplant (tx) was excellent prior to the availability of calcineurin inhibitors (CNIs). Given the nephrotoxicity of CNIs,…
  • 2013 American Transplant Congress

    Has Displaying KDPI in DonorNet® Led to a Spike in Discard Rates for Lower Quality Kidneys?

    D. Stewart, C. Samana, W. Cherikh, R. Formica, J. Friedewald

    UNOS; Yale Med Ctr; Northwestern

    Background: The Kidney Donor Profile Index (KDPI), derived from the Kidney Donor Risk Index (KDRI), began appearing in DonorNet with kidney offers on March 26,…
  • 2013 American Transplant Congress

    Association of Vitamin D and Albuminuria in Renal Transplant Recipients, The

    R. Mainra, A. Hassan, M. Moser, Y. Luo, A. Shoker

    Nephrology, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada; Surgery, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada

    Introduction: Albuminuria is commonly observed in renal transplant recipients and its etiology varies widely. It is associated with poorer graft function and worse patient and…
  • 2013 American Transplant Congress

    IL-33 Receptor Expression by Cardiac and Aortic Allografts Limits Immune Infiltration and Development of Vasculopathy

    Q. Liu, H. Turnquist

    Depart. of Surgery and Immunology, Starzl. Transpl. Inst., Univ. of Pittsburgh Sch. of Med., Pittsburgh, PA

    Overview: Studies have found administration of IL-33 triples the survival of MHC-mismatched murine heart transplants (HTx) in the absence of any immunosupression. These data are…
  • 2013 American Transplant Congress

    Microfluidic-Based Multiplexer for Long-Term Dynamic Islet Culture and Immunosuppression Study

    Q. Wang, F. Feng, Z. Li, M. Nourmohammadzadeh, J. Mendoza-Elias, D. Eddington, J. OBerholzer, Y. Wang

    Surgery, University of Illinois at Chicago, Chicago, IL; Bioenginnering, University of Illinois at Chicago, Chicago, IL

    Purpose: The in vitro study of human islets is often limited by the availability of specific tools. Microfluidic technology has emerged as a hugely promising…
  • 2013 American Transplant Congress

    Transplant Certification and Quality Assessment: The Effect of Center Data Input Quality

    J. Tuttle-Newhall, K. Lentine, D. Axelrod, L. Ware, J. Milton, M. Schnitzler

    Center for Abdominal Transplantation, Saint Louis University, St. Louis; Dartmouth College, Lebanon; University of Texas, San Antonio

    Each transplant program in the United States is required to submit self-reported data to OPTN/UNOS to calculate a center’s performance. Currently, under the Conditions of…
  • 2013 American Transplant Congress

    Successful Ex-Vivo Normothermic Machine Perfusion and Viability Testing of Discarded Human Donor Livers

    S. op den Dries, N. Karimian, M. Sutton, A. Westerkamp, M. Nijsten, A. Gouw, J. Wiersema-Buist, T. Lisman, H. Leuvenink, R. Porte

    Section of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, University Medical Center Groningen, Groningen, Netherlands; Surgical Research Laboratory, Department of Surgery, University Medical Center Groningen, Groningen, Netherlands; Department of Critical Care, University Medical Center Groningen, Groningen, Netherlands; Department of Pathology, University Medical Center Groningen, Groningen, Netherlands

    In contrast to traditional static cold preservation of donor livers, normothermic machine perfusion may reduce preservation injury, improve graft viability, and potentially allows ex-vivo assessment…
  • 2013 American Transplant Congress

    Neutralization of IL-23 Is Protective Against Hepatic Cold Ischemia/Reperfusion (I/R) Injury

    J. Klune, S. Yokota, C. Bartels, N. Murase, Q. Du, D. Geller

    Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA

    Purpose: Interleukin-23 (IL-23) can activate inflammatory pathways such as CD4+ cell differentiation into IL-17 secreting Th17 cell type and increased production of IFNg leading to…
  • 2013 American Transplant Congress

    Pulmonary Hypertension Identified by Color Doppler Echocardiography in Renal Transplant Candidates: Prevalence and Effect on Survival

    A. Ribeiro, M. Gazzana, A. Vicari, M. Knorst, R. Manfro

    Nephrology Department, Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil; Pulmonology Departament, Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil

    Background: Pulmonary hypertension (PH) has been recognized frequently in patients with chronic renal failure undergoing hemodialysis. Some studies have suggested that PH may be associated…
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