2013 American Transplant Congress
Common Rejection Module (CRM) across Multiple Transplant Organs Identifies Novel Therapeutics for Treatment of Acute Rejection in Solid Organ Transplantation, A
We performed meta-analyses of eight datasets comprising whole genome microarray expression profiles on 236 graft biopsy samples from four types of transplanted organs (kidney, lung,…2013 American Transplant Congress
Cardiovascular Disease and Kidney Disease Progression in Kidney Transplant Recipients
Background: Kidney transplant recipients have a high prevalence of cardiovascular disease (CVD) and CVD risk factors, such that CVD is the leading cause of mortality.…2013 American Transplant Congress
For Cause Renal Biopsies Are Heterogeneous Irrespective of Clinical Presentation
St.James's University Hospital, Leeds, United Kingdom
Deteriorating renal function either evidenced by a rise in serum creatinine or proteinuria remains the most important indication for a late transplant biopsy. Over the…2013 American Transplant Congress
Age Disparities in Discussions about Kidney Transplantation among Dialysis Patients
BACKGROUND: Older patients show improved survival and quality of life following kidney transplantation (KT) compared to those who remain on dialysis, yet referral for KT…2013 American Transplant Congress
Human Insulinoma Expression of E2F Reveals a Role in Beta-Cell Proliferation and Quiescence
Surgery - Transplant, University of Illinois at Chicago, Chicago, IL
Reversal of diabetes in patients through islet cell transplant is quickly becoming a reality. However, cadaver organ donations, the current source of islets for transplant,…2013 American Transplant Congress
Six Minute Walk Distance, Sarcopenia and Cardiopulmonary Assessment in Candidates for Liver Transplantation
Evaluation for liver transplantation (LT) focuses on organ-specific testing intended to determine a candidates fitness for transplantation. However, simple tests of global physical function may…2013 American Transplant Congress
Efficient Identification of All Grades of Antibody Mediated Rejection (AMR) and Mixed Rejection with a Unique Immunohistochemical Panel in Heart Transplant Patients
Antibody Mediated Rejection (AMR) following heart transplantation is increasingly recognized as a substantial complication that increases risk for graft failure, vasculopathy, and decreased recipient survival.…2013 American Transplant Congress
Pulmonary Vascular Hemodynamics Improvement with Left Ventricular Assist Devices Unloading Is Sustained after Heart Transplantation
UTAH Cardiac Transplant Program, Salt Lake City, UT
Background:Pulmonary hypertension (PHT) is frequently seen in patients with advanced heart failure (HF) awaiting heart transplantation (HTx). Severe PHT is a contraindication for HTx. Both…2013 American Transplant Congress
Long-Term Persistence of Recipient MHC Class-II Antigen Following Allogeneic Bone Marrow Transplantation
Surgery, Duke University, Durham, NC; Medicine and Immunology, Duke University, Durham, NC
Background: Following allogeneic bone marrow transplantation there is rapid replacement of host antigen presenting cells with donor antigen presenting cells. This has important implications of…2013 American Transplant Congress
Sustained Expression of CD39 Protects Acutely from Renal IRI but Promotes Fibrosis
Background: The adenosinergic axis is involved in renal ischemia reperfusion injury (IRI) and the generation of adenosine by the action of CD39 and CD73 is…
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