ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Pancreas Transplant Outcomes May Be Dependent on Center Experience

    A. Kukla, S. Gustafson, B. Thompson, N. Salkowski, J. Snyder, R. Kandaswamy, A. Israni

    Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis

    Introduction: The number of pancreas transplants (PTx) nationwide is declining, raising concern that some centers may experience low transplant volume; low volume has been associated…
  • 2013 American Transplant Congress

    Racial Differences and Income Disparities Are Associated with Worse Allograft and Death Outcomes in Kidney Transplant Recipients with Lupus Nephritis

    R. Nee, K. Abbott, D. Little, R. Ramsey-Goldman, L. Agodoa, F. Hurst, R. Jindal

    Nephrology, Walter Reed National Military Medical Center, Bethesda, MD; Surgery, Walter Reed National Military Medical Center, Bethesda, MD; Rheumatology, Northwestern University, Chicago, IL; NIDDK, NIH, Bethesda, MD; FDA, Silver Spring, MD

    Background: An analysis of income disparities and racial differences on renal transplant outcomes in recipients with lupus nephritis (LN) has not been reported.Methods: We identified…
  • 2013 American Transplant Congress

    Change of Blood Pressure and Circadian Rhythm after Kidney Transplantation in End Stage Renal Disease Patients, The

    M. Lee, G. An, Y. Cho, H. Whang, J. Kim, B. Chung, B. Choi, C. Park, Y. Kim, C. Yang

    Division of Nephrology, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea

    BackgroundAfter kidney transplantation (KT), many end-stage renal disease (ESRD) patients showed well controlled blood pressure compared to before KT, but the effect of KT on…
  • 2013 American Transplant Congress

    Renal Allograft Tolerance Can Be Achieved in Non-Human Primates Via Delayed Mixed-Hematopoietic Chimerism and Alefacept Treatment

    S. Lee, Y. Yamada, S. Boskovic, M. Atif, M. Tonsho, O. Nadazdin, R. Smith, R. Colvin, J. Allan, J. Madsen, A. Cosimi, G. Benichou, T. Kawai

    Transplant Surgery, Massachusetts General Hospital, Boston, MA; Pathology, Massachusetts General Hospital, Boston, MA

    Renal allograft tolerance has been achieved in MHC-mismatched NHPs and patients via the mixed-chimerism approach. Activation/expansion of donor-reactive CD8+ effector memory T cells (TEMs) represents…
  • 2013 American Transplant Congress

    Antagonists of Bone Morphogenetic Protein Signaling Promote Liver Regeneration and Repair in Mice

    D. Tsugawa, R. Masuzaki, K. Ray, S. Karp

    The Transplant Center and Department of Surgery, Vanderbilt University Medical Center, Nashville, TN

    Pharmacologic agents to enhance liver recovery after injury would have wide therapeutic application. Based on previous work suggesting Bone Morphogenetic Protein (BMP) signaling modulates liver…
  • 2013 American Transplant Congress

    Dual Kidney Transplantation Reduces Organ Wastage and Increases the Number of Kidney Transplants Available to Elderly Candidates

    W. Bry, V. Peddi, H. Mahanty, A. Hassoun, S. Katznelson, P. Patel, L. Bohannon, L. Lu, N. Neidlinger, K. Ueda, R. Osorio

    Department of Transplantation, California Pacific Medical Center, San Francisco, CA

    Changes in national kidney allocation are anticipated to begin in 2014. The proposed system redefines ECD kidneys, resulting in a reduction in both the quantity…
  • 2013 American Transplant Congress

    Phase 3, Double-Blind, Multi-Center, Non-Inferiority, Randomized Study To Examine the Efficacy and Safety of LCP-Tacro™ Tablets, Once Daily, Compared to Prograf® Capsules, Twice Daily, in Combination with Mycophenolate Mofetil in De Novo Adult Kidney Transplantation: Baseline Characteristics, A

    L. Rostaing, K. Budde, S. Bunnapradist

    University Hospital Toulouse-Rangueil, Toulouse, France; Department of Nephrology, Charité Universitätsmedizin, Berlin, Georgia; David Geffen School of Medicine at UCLA, Los Angeles

    This large, multi-continent, Phase 3, double-blind, randomized, active comparator non-inferiority trial will compare efficacy and safety of a once-daily controlled agglomeration formulation of tacrolimus with…
  • 2013 American Transplant Congress

    Superior Renal Function in an Everolimus-Based Calcineurin Inhibitor Free Regimen Compared to Standard Cyclosporine/Mycophenolate and Low Cyclosporine/Everolimus: Follow-Up of the HERAKLES Study at Month 24

    K. Budde, W. Arns, C. Sommerer, F. Lehner, M. Zeier, H. Neumayer, M. Guba, J. Jacobi, P. Weithofer, C. May, D. Baeumer, E. Paulus, O. Witzke

    HERAKLES Study Group, Germany; Novartis Pharma, Nuremberg, Germany

    Aim: To follow up (FU) on the evolution of renal function (RF) of immunosuppressive regimens with different calcineurin inhibitor (CNI) exposure at month (Mo)24 post…
  • 2013 American Transplant Congress

    Kidney Discard Reasons by Kidney Donor Profile Index (KDPI)

    L. Malinzak, A. Patel, M. Goggins, J. Denny, D. Kim, L. Yessayan, M. Weitzer

    Transplant Institute, Henry Ford Health System, Detroit, MI; School of Medicine, Wayne State University, Detroit, MI

    KDPI summarizes the risk of donor kidney graft failure based on clinical and demographic parameters. We hypothesize that discard of a kidney with low KDPI…
  • 2013 American Transplant Congress

    Single Donor-Derived Strongyloides in Solid Organ Transplants

    M. Le, H. Clauss, J. Pasko, K. Ravin, D. Muchant, A. Hasan, A. Kotru, C. Varma, G. Cipollina

    Geisinger Medical Center, Danville; Temple University Hospital, Philadelphia

    CDC was notified of Strongyloides infection in transplant recipients of kidneys, pancreas and heart from same deceased donor. Concern for donor-derived strongyloidiasis prompted an investigation…
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