2013 American Transplant Congress
Chimeric Antibody Against LFA-1 Does Not Synergize with Belatacept in Primate Renal Transplantation, A
Background: Clinical studies with belatacept have shown improved graft function at the cost of increased rates of and more severe early rejection. Blockade of LFA-1…2013 American Transplant Congress
Nanostructural Alteration of Blocking Activation of CD8+ T Cells Utilizing Atomic Force Microscopy
PurposeThis research investigated the nanostructural alterations in blocking T cell activation using atomic force microscopy (AFM).MethodsCD8+ T cells were isolated from the spleens of C57BL/6…2013 American Transplant Congress
Inflammatory Bowel Disease in Renal Transplant Recipients: A Retrospective Multicenter Study
Inflammatory bowel disease (IBD) can occur before or, despite corticoids and immunosuppressive treatment, after transplantation. We collected characteristics of cases of IBD in renal transplant…2013 American Transplant Congress
Neurokinin-1 Receptor-Signaling of T Cells and Dendritic Cells Is Required for Optimal Elicitation of the T-Cell Response That Leads to Graft Rejection
Increasing evidence suggests that elicitation of donor–reactive T-cell immunity is regulated by pro-inflammatory neuropeptides. Substance P (SP) is the prototypic pro-inflammatory neuropeptide released by leukocytes…2013 American Transplant Congress
Does Length of Hospital Stay and Hospital-Wide Incidence Have an Impact on Clostridium Difficile Infection (CDI) in Organ Transplant Recipients?
University of North Carolina, Chapel Hill
Several risk factors contributing to CDI have been identified in organ transplant recipients (Txs)(Transplantation 2012; 93:1051-57). Among these factors is hospital length of stay (LOS).…2013 American Transplant Congress
Multi-Center, International Registry of Cardiac Transplantation for Light Chain (AL) and Transthyreitin (TTR) Amyloidosis, A
BackgroundAL and TTR cardiac amyloid has a median survival of only 6-8 months, untreated. Orthotopic heart transplant (OHT) followed by stem cell transplant (SCT) for…2013 American Transplant Congress
Extended-Release Tacrolimus Therapy Is Effective and Safe in De Novo Kidney Transplant Recipients from Living and Expanded, Standard, or after Cardiac Death Deceased Donors
Nephrology, Hospital 12 de Octubre, Madrid, Spain
Nonadherence is one of the most important causes of late renal graft loss. A single daily dose of tacrolimus in the morning beginning immediately after…2013 American Transplant Congress
Serum and Urine IP–10 and Fractalkine Are Effective Biomarkers for Prediction of Early Kidney Transplant Rejection
Background: Chemotactic factors play an important role in acute rejection. The aims of our study were to examine the expression of serum and urine IP-10…2013 American Transplant Congress
IL-1 Receptor Antagonist Treatment Rescues Impact of Brain Death Related Inflammation in Liver of Non-Human Primates
University of Wisconsin, Madison
Donor liver quality is critical to avoid primary non-function or dysfunction after transplantation. Previously, our lab developed a model of Non-human Primate (NHP) Brain death…2013 American Transplant Congress
MFI TRAP: HLAmatchmaker Can Help To Do the Reactions Patterns of DSA Versus NDSA To Assess Risk of Graft Failure by AMR, THE
The HLAMatchmaker (HLAMM) evaluates the compatibility between donor and recipient through comparisons within and between loci, and determines which epitopes in HLA mismatched are different…
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