2013 American Transplant Congress
Proton Beam Radiotherapy (PBRT) Versus Tace for Hepatocellular Carcinoma (HCC) Prior to Liver Transplantation (LT)
We retrospectively analyzed our long term experience on the use of PBRT versus TACE for downstaging or bridge therapy of HCC prior to LT. Methods:…2013 American Transplant Congress
MicroRNA 194 Regulates Apoptosis in Epstein Barr Virus+ B Cell Lymphomas Associated with Post-Transplant Lymphoproliferative Disorder
Surgery, Stanford University School of Medicine, Stanford, CA
Post-Transplant Lymphoproliferative Disease (PTLD) is a potentially fatal side effect of the immunosuppressive agents used to prevent allograft rejection. PTLD is associated with Epstein-Barr Virus…2013 American Transplant Congress
Inhibition of IL6 Mediated Th17 Differentiation Via BATF Signaling Prevents the Development of Obliterative Airway Disease Induced by Antibodies to MHC Molecules
Surgery, Pathology & Immunology, Washington University School of Medicine, St. Louis, MO
Background: Development of donor specific antibodies has been shown to precede the development of chronic rejection, bronchiolitis obliterans syndroms (BOS) following human lung transplantation. Using…2013 American Transplant Congress
Kidney Transplant Graft Loss – Continued Room for Improvement
Identification of causes of graft loss (GL)allows targeted preventive therapies. We studied actuarial GL in 5 decades (1960-2010), for adult 1st kidney tx recips. Donor…2013 American Transplant Congress
Indirect CD4 T Cell Allorecognition of MHC Class II Alloantigen Is Limited by Adaptive Immunity
Surgery, Cambridge University, Cambridge, United Kingdom
IntroductionWe have previously described a partially-mismatched [bm12.Kd.IE (IAbm12, IEd, Kd, Kb, Db) to C57BL/6] model of chronic cardiac allograft rejection, and demonstrated surprisingly that indirect…2013 American Transplant Congress
Natural Killer Cells Cause Apoptotic Cell Death and Micro-Inflammation in Early Mouse Kidney Allografts
University of Alberta, Edmonton, Canada
The roles of natural killer (NK) cells in organ transplant injury and rejection are largely unknown. This is of particular interest, because current immunosuppressive drugs…2013 American Transplant Congress
Late after Lung Transplantation Many Patients Have Donor-Specific HLA Antibodies (DSA) and High DSA Levels Appear To Be Associated with Poor Outcomes
The presence of DSA after lung transplantation has been associated with adverse outcomes, but the utility of long-term routine screening remains controversial. For lung recipients…2013 American Transplant Congress
Liver Transplantation for Polycystic Liver Disease: A 20-Year Experience
Surgery, University of California, Los Angeles, CA
Introduction: Polycystic liver disease (PCLD) can lead to massive, highly symptomatic hepatomegaly and a reduced quality of life. While hepatic resection and cyst fenestration can…2013 American Transplant Congress
Serum and Urinary Neutrophil Gelatinase-Associated Lipocalin as Predictive Biomarker for Acute Rejection and Delayed Graft Function after Kidney Transplantation
PURPOSE: Neutrophil gelatinase-associated lipocalin (NGAL) has emerged an early marker protein for kidney dysfunction in various clinical settings. Data on NGAL expression during acute rejection…2013 American Transplant Congress
Laparoendoscopic Single Site Donor Nephrectomy Offers Better Cosmesis, and Comparable Surgical Outcomes to Conventional Retroperitoneoscopic Surgery
Objectives: Retroperitoneoscopic Donor Nephrectomy (RPLDN) has been our standard care for living donors, using 3 flank ports and Pfannenstiel extraction. Our conventional strategy for RPLDN…
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