ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Impact of Donor and Recipient Pretransplant EBV Antibody Status on PTLD Incidence in Adult Kidney Transplant Recipients

    N. Chandolias, K. Gillingham, H. Balfour, Jr, A. Matas

    Surgery and Lab Medicine and Pathology, U Mn, Mpls, MN

    We studied the impact of pretransplant (pretx) EBV antibody (ab) status on the incidence of PTLD in adult primary kidney tx recipients. Between 1/2002 and…
  • 2013 American Transplant Congress

    TIM-1 Mucin Domain Is Critical in Breg Development, Induction, and Functional Activity

    Y. Wang, M. Yeung, T. Ueno, V. Kuchroo, S. Xiao, N. Najafian, Q. Ding, D. Rothstein

    University of Pittsburgh, Pittsburgh, PA; Harvard Medical School, Boston, MA

    Bregs play a key role in immune tolerance by negatively regulating immune responses via IL-10. We showed that TIM-1 is an inclusive marker for IL-10+…
  • 2013 American Transplant Congress

    Specific Lymphocyte Trafficking Via High Endothelial Venules Is Required for Tolerance

    B. Burrell, J. Bromberg

    University of Maryland, Baltimore

    Background: CD40-CD40L costimulatory blockade plus donor-specific splenocyte transfusion (DST) induces tolerance concurrent with regulatory T cell (Treg) induction in the lymph node (LN). Treg are…
  • 2013 American Transplant Congress

    Standardization of CMV DNA Viral Load Monitoring

    B. Cobb, D. Boisvert, S. Lee, P. Baum, R. Razonable, A. Caliendo, A. Asberg, J. Yao, T. Do

    Roche, Pleasanton, CA; Mayo Clinic, Rochester, MN; Emory University, Atlanta, GA; University of Oslo, School of Pharmacy, Oslo, Norway

    Background: The clinical utility of cytomegalovirus (CMV) viral load (VL) testing for managing transplant recipients and other immunocompromised patients has been established based on the…
  • 2013 American Transplant Congress

    Change in Glomerular Filtration Rate (GFR) in the First Year Post Liver Transplant

    W. Bush, R. Mangus, A. Lutz, J. Fridell, R. Vianna, C. Kubal, A. Tector

    Transplant Division, Dept of Surgery, Indiana University, School of Medicine, Indianapolis, IN

    Baseline renal function is an important factor in post liver transplant (LT) outcome. This study examines the change in glomerular filtration rate (GFR) in the…
  • 2013 American Transplant Congress

    Efficacy and Safety of Influenza Vaccination during the First Six Months Post-Transplantation

    E. Cordero, A. Bulnes-Ramos, T. Aydillo, B. Leon-Jimenez, J. Torre-Cisneros, R. Lara, J. Gavalda, M. Gentil, M. Gomez, E. Lage, P. Perez-Romero

    Enfermedades Infecciosas, Microbiología y Medicina Preventiva, IBIS, Hospital Virgen del Rocío, Sevilla, Spain; Enfermedades Infecciosas y Servicio de Cardiología, IMIBIC, Hospital Universitario Reina Sofia, Cordoba, Spain; Enfermedades Infecciosas, Hospital Vall d´Hebron, Barcelona, Spain; Servicio de Nefrología, Hospitales Virgen del Rocío, Sevilla, Spain; Trasplante Hepático y Cirugía Hepatobiliopancrática, Hospitales Virgen del Rocío, Sevilla, Spain; Servicio de Cardiología, Hospitales Virgen del Rocío, Sevilla, Spain

    Our goal was to study the efficacy and safety of influenza vaccination during the first six months post-transplantation.A prospective cohort study of consecutive cases of…
  • 2013 American Transplant Congress

    Kidney Allograft Function and Histology in Recipients Dying with a Functioning Graft

    E. Lorenz, Z. El-Zoghby, H. Amer, P. Dean, W. Kremers, M. Stegall, F. Cosio

    William von Liebig Transplant Center, Mayo Clinic, Rochester, MN

    Introduction: Death with function (DWF) is a major cause of kidney allograft failure. However, few studies have examined the relationship between kidney allograft function and…
  • 2013 American Transplant Congress

    Donation after Circulatory-Death in the UK

    D. Summers, R. Johnson, D. Collett, G. Randhawa, P. Murphy, C. Watson, J. Neuberger, M. Mallik, A. Bradley

    Department of Surgery, University of Cambridge, Cambridge, United Kingdom; Organ Donation and Transplantation, NHS Blood and Transplant, Bristol, United Kingdom

    Background: The number of deceased donors in the UK has increased from 809 in 2007-8 to 1088 in 2011-2. This increase can be ascribed, predominantly,…
  • 2013 American Transplant Congress

    YAP Phosphorylation Is Altered during Liver Regeneration in a Rat Hepatectomy Model

    J. Grijalva, F. Camargo, G. Sadri-Vakili, K. Vakili

    Department of Surgery, Boston Children's Hospital, Boston, MA; Department of Stem Cell and Regenerative Biology, Harvard University, Boston, MA; MassGeneral Institute For Neurodegenerative Disease, Massachusetts General Hospital, Boston, MA

    Purpose:The transcription factor YAP has been shown to stimulate hepatocyte proliferation. Furthermore, overexpression of YAP results in liver overgrowth leading to transformation into malignancy. Phosphorylation…
  • 2013 American Transplant Congress

    Blockade of Phagocytosis Accelerates Cardiac Allograft Rejection

    B. Snawder, T. Shimizu, M. McGrath, N. Najafian, M. Yeung

    Transplantation Research Center, Brigham&Women's Hospital, Boston, MA

    Under physiological conditions, prompt clearance of dying cells provides protection from the release of pro-inflammatory contents, induces T cell tolerance to self-antigens and prevents autoimmunity.…
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