2013 American Transplant Congress
Differential Depletion and Recovery of Lymphocyte Subsets in Lymph Nodes of Alemtuzumab-Treated Cynomolgus Monkeys
Background: Alemtuzumab (Campath-1H) is a humanized mAb directed against CD52 that depletes circulating but not bone marrow lymphocytes. A transient increase in proportion of circulating…2013 American Transplant Congress
Results of Response Guided Therapy (RGT) Using Telaprevir in Liver Transplant Recipients with Hepatitis C Virus (HCV) Recurrence: A Single Center Experience of 18 Patients
The Liver Institute, Methodist Dallas Medical Center, Dallas, TX
Introduction: There is no data on response guided therapy in liver transplant recipients with HCV genotype I recurrence.Aim: This is a Clinical Protocol developed to…2013 American Transplant Congress
Perceived Barriers to Adherence in Pediatric Transplantation from the Guardian’s Perspective
Adolescents have increased non-adherence risk. Comparisons of perceived barriers to adherence in pediatric and adolescent solid organ transplant recipients (SOT) have not been conducted.15 US…2013 American Transplant Congress
National Survey of Kidney Transplant Centres: Policy on Morbid Obesity in the Transplant Patient
Hopital Maisonneuve-Rosemont, Montreal, QC, Canada
Morbid obesity is common in the dialysis population, for whom weight loss is difficult due to fatigue and malaise. Post-transplantation, obesity is further exacerbated due…2013 American Transplant Congress
Comparison of Resource Utilization between Three Induction Regimens in Kidney Transplant Recipients
Medicine, Surgery, Medical University of South Carolina, Charleston, SC
Induction therapy is commonly used in kidney transplantation due to its ability to decrease the frequency of early acute rejection; it is associated with higher…2013 American Transplant Congress
Proton Beam Radiotherapy (PBRT) Versus Tace for Hepatocellular Carcinoma (HCC) Prior to Liver Transplantation (LT)
We retrospectively analyzed our long term experience on the use of PBRT versus TACE for downstaging or bridge therapy of HCC prior to LT. Methods:…2013 American Transplant Congress
MicroRNA 194 Regulates Apoptosis in Epstein Barr Virus+ B Cell Lymphomas Associated with Post-Transplant Lymphoproliferative Disorder
Surgery, Stanford University School of Medicine, Stanford, CA
Post-Transplant Lymphoproliferative Disease (PTLD) is a potentially fatal side effect of the immunosuppressive agents used to prevent allograft rejection. PTLD is associated with Epstein-Barr Virus…2013 American Transplant Congress
Inhibition of IL6 Mediated Th17 Differentiation Via BATF Signaling Prevents the Development of Obliterative Airway Disease Induced by Antibodies to MHC Molecules
Surgery, Pathology & Immunology, Washington University School of Medicine, St. Louis, MO
Background: Development of donor specific antibodies has been shown to precede the development of chronic rejection, bronchiolitis obliterans syndroms (BOS) following human lung transplantation. Using…2013 American Transplant Congress
Kidney Transplant Graft Loss – Continued Room for Improvement
Identification of causes of graft loss (GL)allows targeted preventive therapies. We studied actuarial GL in 5 decades (1960-2010), for adult 1st kidney tx recips. Donor…2013 American Transplant Congress
Indirect CD4 T Cell Allorecognition of MHC Class II Alloantigen Is Limited by Adaptive Immunity
Surgery, Cambridge University, Cambridge, United Kingdom
IntroductionWe have previously described a partially-mismatched [bm12.Kd.IE (IAbm12, IEd, Kd, Kb, Db) to C57BL/6] model of chronic cardiac allograft rejection, and demonstrated surprisingly that indirect…
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