2013 American Transplant Congress
Excellent Outcomes with Transplantation of Kidneys (KTx) from Deceased Donors (DDs) with Acute Kidney Injury (AKI)
Background:AKI is common among DDs and results in high discard rates. In contrast, we have consistently used kidneys from DDs with AKI. We studied our…2013 American Transplant Congress
Quantitative Relationship of Luminex Single Antigen Bead Assay (LSA), Antibody Titration and Flow Crossmatch in Heart Transplantation – A Data Analysis of 5 Years Clinical Testing
Clinical Transplantation Immunology Lab, Duke University Medical Center, Durham, NC
Donor selecting avoiding unacceptable HLA antigens (UAs) efficiently facilities heart transplant without performing a final flow crossmatch (FCXM) prior to transplant. Luminex single antigen bead…2013 American Transplant Congress
Inequitable Access to Deceased Donor Kidney Transplantation (KTx) in a State with Multiple Donor Service Areas (DSAs)
North Austin Medical Center, Austin, TX
INTRO: Inequities (ineqs) in access to KTx date from the inception of the nationalized allocation system and remain a serious problem. The present study examines…2013 American Transplant Congress
Molecular Landscape of T Cell-Mediated Rejection: The T Cell Synapse Emerges, The
University of Alberta, Edmonton, Canada
The molecular landscape of T cell-mediated rejection (TCMR) is obscured by secondary inflammation and injury. We hypothesized the transcripts most highly associated with TCMR would…2013 American Transplant Congress
Should Repeat HLA Mismatches Be Avoided in Lung ReTransplants?
Cleveland Clinic, Cleveland, OH
De Novo DSA is associated with increased risk of Bronchiolitis Obliterans Syndrome (BOS) and lung allograft loss, however the characteristics of De Novo DSA that…2013 American Transplant Congress
Correlations of In Vitro Islet Potency Tests with Clinical Islet Auto-Transplant Outcome
There is a critical need for real-time in vitro islet characterization assays that are predictive of clinical transplant outcomes (CTO), but none is available so…2013 American Transplant Congress
Association of HLA-A, B, C, DR, and DQ Matching with Rejection and Survival in Pancreas Transplantation
University of Minnesota, Minneapolis, MN
Objective: Determine the impact of HLA matching on acute cellular rejection (ACR), and graft and patient survival in pancreas txp.Methods: Retrospective review of 1,063 sequential…2013 American Transplant Congress
Protection from Prolonged Cold Ischemia (CI) of Several Days Duration Is Mediated by Anti-Apoptotic phosphoBAD during Hibernation
Donor kidney cold (4°C) ischemia (CI) of >30 hrs is associated with increased apoptosis of renal tubular epithelial cells (RTEC) and is an important cause…2013 American Transplant Congress
Liver Transplantation (LT) in Patients Receiving Renal Replacement Therapy (RRT): Predicting Renal Recovery and Post-Transplant Futility
Surgery, UCLA, LA, CA; Anesthesiology, UCLA, LA, CA
Background: The Model for End-Stage Liver Disease (MELD) system prioritizes liver allocation to patients in renal failure, increasing the number of simultaneous liver-kidney transplants (SLK).…2013 American Transplant Congress
Renal Transplant Recipients with Positive Donor Specific Antibodies Maintain Stable Graft Function with Mycophenolic Acid Escalation
Background: Donor-specific HLA antibody (DSA) formation in post-renal transplant patients is associated with chronic rejection and graft failure. IgG3 DSA has been associated with poorer…
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