2013 American Transplant Congress
Relationship of Kidney Length, Volume and Renal Split Function in Living Kidney Donors
Purpose: All potential living donors at Columbia University Medical Center (CUMC) undergo abdominal CT imaging including estimation of kidney volume and length. Subjects with >…2013 American Transplant Congress
Validating the Microarray Test for Antibody-Mediated Rejection in a Prospective Trial: The INTERCOM Study
We previously developed a microarray-based test for antibody-mediated rejection (ABMR) in biopsies from renal transplants. To validate it, we undertook the INTERCOM study, a prospective…2013 American Transplant Congress
Cytokine Measurement by High-Sensitivity Milliplex Assay in Cell Suspensions Obtained during Usual Kidney Allograft Biopsies
Division of Nephrology, University of Washington, Seattle, WA
PURPOSE: The purpose of the study was to determine if cytokines could be measured from the supernatant of kidney biopsy cell suspensions and if measured…2013 American Transplant Congress
Alloantibody-Induced C4d Deposition, without Activation of Distal Complement Effectors C5a and C5b-9, Is Not Associated with Kidney Allograft Injury or Accommodation in Mice
University of Alberta, Edmonton, Canada
Complement split product C4d deposition in human organ transplants is a biomarker of classical complement activation triggered by antibody binding to donor antigens, but this…2013 American Transplant Congress
Sitagliptin, DPP- IV Inhibitor, Protects Against Tacrolimus-Induced Diabetes in Rats
The pathogenesis of post-transplant diabetes mellitus is thought to be partly related to the direct toxic effect of tacrolimus on pancreas and the resultant decrease…2013 American Transplant Congress
Splenic Artery Embolization in Liver Transplantation: A Single Center 5 Year Experience
Background:Severe portal hyperperfusion after liver transplantation has been shown to cause intrahepatic arterial vasoconstriction secondary to increased washout of adenosine (hepatic artery buffer response). Furthermore,…2013 American Transplant Congress
Novel Strategy To Prevent HCV Re-Infection Post Liver Transplantation: Anti-E1/E2 Monoclonal Antibody and Epigallocatechin Gallate (EGCG) in Combination, A
University of Alberta, Edmonton, Canada
Background: Prophylaxis against HCV infection of the naÏve allograft is integral to efforts to improve outcomes in HCV positive liver transplant recipients. To effectively achieve…2013 American Transplant Congress
Validating the Microarray Test for T Cell-Mediated Rejection in Biopsies in a Prospective Trial: The INTERCOM Study
We previously reported a microarray-based test for T cell-mediated rejection (TCMR) in biopsies from renal transplants. To validate this test, we undertook a prospective international…2013 American Transplant Congress
Role of Estimated GFR CKD-EPI as Screening Tool for Donor Selection
Purpose: Living donor selection usually includes a measured renal function rather than estimated GFR (eGFR) equations, such as CKD-EPI because of concerns of accuracy. However,…2013 American Transplant Congress
Tumor Necrosis Factor Receptor Type 2 Expression on Regulatory T Cells Predicts Acute Kidney Injury after Kidney Transplantation
Multi-Organ Transplant Program, McGill University Health Centre, Montreal, QC, Canada
Background: Acute kidney injury (AKI) leads to worse graft outcomes after kidney transplantation. Tumor necrosis factor (TNF) is classically a mediator of AKI. Recent evidence,…
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