Am J Transplant, Volume 3, Suppl 5 Archives - Page 119 of 178 - ATC Abstracts

2013 American Transplant Congress
Optimization of the Coating of Pancreatic Islets with T Regulatory Cells in the Novel Immunoprotective Approach
K. Golab, S. Kizilel, T. Bal, M. Hara, M. Zielinski, X. Wang, J. Grzanka, L. Wang, O. Cochet, M. Tibudan, P. Witkowski
Department of Surgery, University of Chicago, Chicago, IL; Department of Chemical and Biological Engineering, College of Engineering, Koc University, Istanbul, Turkey; Department of Medicine, University of Chicago, Chicago, IL
Aim. T regulatory cells (Tregs) possess immunosuppressive properties and can serve as an effective therapy in transplantation. Recently, we have shown that Tregs can be…
2013 American Transplant Congress
Tuning the OPTN's KPD Optimization Algorithm To Incentivize Centers To Enter Their "Easy-to-Match" Pairs
D. Stewart, R. Leishman, E. Sleeman, C. Monstello, G. Lunsford, J. Maghirang, T. Sandholm, S. Gentry, R. Formica, J. Friedewald, K. Andreoni
UNOS; Carnegie Mellon Univ; Johns Hopkins Univ & USNA; Yale Medical Ctr; Northwestern; Univ of Florida
Background: Currently, priority points are awarded in the OPTN Kidney Paired Donation Pilot Program's (KPDPP) optimization algorithm as follows: zero mismatch (200 pts), highly sensitized…
2013 American Transplant Congress
Viral Determinants of Pathogen Induced Alloantibody Production
R. Ruhil, O. Bulut, S. Talebagha, B. Oh, V. Lu, S. Knechtle, N. Iwakoshi
Emory Transplant Center, Atlanta
Background: The appearance of alloantibody can initiate the onset of rapid and destructive antibody-mediated rejection (AMR) or have no demonstrable acute effects. The factors determining…
2013 American Transplant Congress
CMV Serostatus Correlation with Early Kidney Allograft Transcriptome Change in the GOCAR Cohort
A. Le Page, W. Zhang, B. Murphy, B. Nankivell, J. Chapman, P. O'Connell, S. Alexander, W. Rawlinson
University of NSW, Randwick, Australia; Mt Sinai School of Medicine, New York; Westmead Hospital, Westmead, Australia; The Children's Hospital Westmead, Westmead, Australia
Identifying transcriptional change in renal allografts infected with Cytomegalovirus (CMV) may be important in understanding CMV effects on graft rejection and injury.We examined transcriptional profiles…
2013 American Transplant Congress
Late Antibody-Mediated Rejection (AMR) after Kidney Transplantation
M. Martina, F. Oppenheimer, I. Revuelta, J. Campistol Planas, M. Sole, J. Cid, F. Diekmann
Nephrology, Hospital Clinic, Barcelona, Spain; Hematology, Hospital Clinic, Barcelona, Spain; Pathology, Hospital Clinic, Barcelona, Spain
INTRODUCTION: Late AMR can develop at any time post kidney transplantation and represents a major challenge.OBJECTIVE: To characterize a series of kidney transplant recipients with…
2013 American Transplant Congress
Pivotal Circulating Antibody Panel for Pre-Transplant Prediction of FSGS Recurrence after Kidney Transplantation, A
M. Sarwal, M. Delville, T. Sigdel, C. Wei, A. Fernoni, G. Burke, M. Naesens, A. Jackson, N. Alachkar, G. Canaud, C. Legendre, J. Reiser, D. Anglicheau
California Pacific Medical Center, San Francisco; Department of Kidney Transplantation, Necker Hospital, Paris, France; Division of Transplant Surgery, University of Miami School of Medicine, Miami; Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium; The Johns Hopkins Incompatible Kidney Transplant Team, John Hopkins, Baltimore
Introduction: Recurrence of focal segmental glomerulosclerosis (rFSGS) after kidney transplantation leads to graft loss. The identity of the involved antibodies and specific immunogenic epitopes remains…
2013 American Transplant Congress
Outcome Reporting in Randomised Controlled Trials (RCTs) of Primary Immunosuppression in Kidney Transplantation
P. Masson, F. Duthie, P. Kelly, G. Higgins, J. Craig, A. Webster
Sydney School of Public Health, University of Sydney, Sydney, NSW, Australia; Cochrane Renal Group, Centre for Kidney Research, Sydney, NSW, Australia; Department of Renal Medicine, Royal Infirmary of Edinburgh, Edinburgh, Scotland, United Kingdom; Centre for Renal and Transplant Research, Westmead Hospital, Sydney, NSW, Australia
Aims: To estimate the proportion of contemporary RCTs of primary immunosuppression in kidney transplantation reporting specified patient and graft-related outcomes, objectively measure reporting quality and…
2013 American Transplant Congress
Regulation of Serological Alloreactive Memory by Pathogen Infection, The
R. Ruhil, O. Bulut, S. Talebagha, B. Oh, V. Lu, S. Knechtle, N. Iwakoshi
Emory Transplant Center, Atlanta
The breadth and strength of HLA specific antibodies (HSA) have a significant impact on waiting times for transplantation and the presence of HSA prior to…
2013 American Transplant Congress
Relationship of Kidney Length, Volume and Renal Split Function in Living Kidney Donors
S. Fernandez, S. Mohan, Z. Zaky, J. Crew, J. Dube, M. Carrol, J. Wexler, L. Ratner, D. Cohen, B. Tanriover
Nephrology, Columbia University Medical Center, New York, NY; Surgery, Columbia University Medical Center, New York, NY
Purpose: All potential living donors at Columbia University Medical Center (CUMC) undergo abdominal CT imaging including estimation of kidney volume and length. Subjects with >…
2013 American Transplant Congress
Validating the Microarray Test for Antibody-Mediated Rejection in a Prospective Trial: The INTERCOM Study
A. Pereira, J. Reeve, J. Chang, A. Matas, D. de Freitas, J. Bromberg, J. Sellares, G. Einecke, P. Halloran
University of Alberta, Edmonton, Canada; University of Minnesota, Minneapolis; Manchester Royal Infirmary, Manchester, United Kingdom; University of Maryland School of Medicine, Baltimore; Hospital de la Vall d'Hebron, Barcelona, Spain; Medical School of Hannover, Hannover, Germany
We previously developed a microarray-based test for antibody-mediated rejection (ABMR) in biopsies from renal transplants. To validate it, we undertook the INTERCOM study, a prospective…