2013 American Transplant Congress
Bortezomib Impacts T-Cell Signaling and Regulatory Pathways
Med. Univ South Carolina, Charleston; Cleveland Clinic, Cleveland; Emory University, Atlanta
Introduction/ Aims: Bortezomib (PS-341), a selective 26S proteasome inhibitor has been used to treat antibody mediated rejection (AMR) among allograft recipients. The efficacy of Bortezomib…2013 American Transplant Congress
Outcomes in Lung Transplantation: The RIFLE Classification Optimizes the Predictive Utility of Post-Transplant Acute Kidney Injury as a Determinant of Early and Late Outcomes
The purpose of this study is to compare two methods of classifying acute kidney injury (AKI), the Risk, Injury, Failure, Loss, End stage (RIFLE) and…2013 American Transplant Congress
Gene Expression Assessment in Kidney Transplant Biopsies To Predict Outcomes in Antibody-Mediated Rejection
Antibody-mediated rejection (ABMR) is a major cause of kidney transplant failure, but the determinants of outcome are poorly defined. We hypothesized that disease activity and…2013 American Transplant Congress
Preexisting Donor Specific Antibody (DSA) with a Negative Flow Crossmatch (FCXM) Should Not Preclude Kidney Transplantation
University of Alabama at Birmingham, Birmingham
Background: DSA is associated with increased risk for acute antibody mediated rejection (AMR). The optimal immunosuppression strategy for FCXM negative (-) DSA positive (+) renal…2013 American Transplant Congress
Optimization of the Coating of Pancreatic Islets with T Regulatory Cells in the Novel Immunoprotective Approach
Aim. T regulatory cells (Tregs) possess immunosuppressive properties and can serve as an effective therapy in transplantation. Recently, we have shown that Tregs can be…2013 American Transplant Congress
Rate and Causality of Thirty-Day Readmissions Following Renal Transplantation
Glickman Urological & Kidney Institute, Cleveland Clinic, Cleveland, OH
Introduction: The Affordable Care Act, added to the Social Security Act, established the Hospital Readmission Reduction Program which will penalize hospitals with excessive 30-day readmissions…2013 American Transplant Congress
Single Center Experience with Long-Term Prospective BK Monitoring in Renal Transplantation
Prospective screening for BK viremia (BKV) in renal transplant recipients (RTR) may allow earlier detection of BKV reactivation and prevent BKV nephropathy (BKVN). However, utility…2013 American Transplant Congress
Pivotal Circulating Antibody Panel for Pre-Transplant Prediction of FSGS Recurrence after Kidney Transplantation, A
Introduction: Recurrence of focal segmental glomerulosclerosis (rFSGS) after kidney transplantation leads to graft loss. The identity of the involved antibodies and specific immunogenic epitopes remains…2013 American Transplant Congress
Outcome Reporting in Randomised Controlled Trials (RCTs) of Primary Immunosuppression in Kidney Transplantation
Aims: To estimate the proportion of contemporary RCTs of primary immunosuppression in kidney transplantation reporting specified patient and graft-related outcomes, objectively measure reporting quality and…2013 American Transplant Congress
Regulation of Serological Alloreactive Memory by Pathogen Infection, The
Emory Transplant Center, Atlanta
The breadth and strength of HLA specific antibodies (HSA) have a significant impact on waiting times for transplantation and the presence of HSA prior to…
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