ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Association between the CYP3A5*1 Allele, Tacrolimus Concentrations and Renal Function in Lung Transplant Recipients

    K. Schoeppler, T. Kiser, C. Aquilante, D. Fish, M. Zamora

    Pharmacy, University of Colorado Hospital, Aurora, CO; University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO; Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO

    Dose-adjusted tacrolimus (TAC) trough levels (ng/ml per mg/day, L/D) are significantly lower in lung transplant recipients (LTxR) who are CYP3A5 expressors (*1/*1 or *1/*3) versus…
  • 2013 American Transplant Congress

    Intraoperative Renal Replacement Therapy during Liver Transplant: Outcomes of 105 Cases

    M. Mai, R. Brotman, H. Wadei, M. Prendergast, K. Oshel, B. Taner, A. Keaveny, T. Gonwa

    Mayo Clinic, Jacksonville, FL

    Renal dysfunction in liver transplant (LT) candidates increases intraoperative risks. One year survival in patients requiring pre or post operative renal replacement therapy (RRT) is…
  • 2013 American Transplant Congress

    Gastric Fundoplication To Prevent Reflux Symptoms in Stomach Transplantation

    R. Mangus, A. Tector, C. Kubal, J. Fridell, R. Vianna

    Transplant Division, Dept of Surgery, Indiana University School of Medicine, Indianapolis, IN

    IntroductionTransplantation of the stomach occurs as part of a multivisceral or modified multivisceral transplant. Severe gastroesophageal reflux (GER) is a common complication associated with stomach…
  • 2013 American Transplant Congress

    Tacrolimus-Induced Diabetes Compared to Cyclosporine May Lead to More Diabetic Complications Post Heart Transplant

    J. Patel, M. Kittleson, M. Rafiei, A. Osborne, D. Chang, L. Czer, J. Kobashigawa

    Cedars-Sinai Heart Institute, Los Angeles, CA

    BACKGROUND: Cyclosporine (CSA) and tacrolimus (TAC) are the main immunosuppressive agents in heart transplantation. Both CSA and TAC are diabetogenic, however, in clinical practice, TAC…
  • 2013 American Transplant Congress

    Pre-Transplant Cardiovascular Risk Factors Improve the SRTR Cox Proportional Hazard Model for 1 Year Patient Survival after Deceased Donor Kidney Transplant

    R. Pelletier, A. Rajab, T. Pesavento, M. Henry

    Surgery/Transplantation, The Ohio State University Wexner Medical Center, Columbus, OH

    Background:Debate continues regarding the utility of including additional clinical variables to improve SRTR center-specific predicted outcomes. In this study we used a cohort of kidney…
  • 2013 American Transplant Congress

    Presence of Preformed IgG3 DSA Identifies Patients at Higher Risk of Early Rejection in Liver Transplantation

    H. Kaneku, J. O'Leary, N. Bañuelos, L. Jennings, B. Susskind, G. Klintmalm, P. Terasaki

    UCLA, Los Angeles, CA; Baylor University Medical Center, Dallas, TX; Terasaki Foundation Laboratory, Los Angeles, CA

    Aim: to examine the impact of preformed IgG3 donor-specific HLA antibodies (DSA) in early acute rejection after liver transplantation (LT).Methods: We analyzed 1271 adult LT…
  • 2013 American Transplant Congress

    KDRI Scores Did Not Correlate with Allograft Survival ForA Cohort of HIV (+) Kidney Transplant Recipients

    G. Malat, K. Ranganna, S. Guy, G. Xiao, D. Reich, A. Doyle

    Drexel University College of Medicine, Philadelphia, PA

    Background: The KDRI score has emerged as an important tool to assess donor characteristics that are associated with differences in graft survival. How KDRI scores…
  • 2013 American Transplant Congress

    Durability of Pancreatic Islets Transplantation in Brittle Type 1 Diabetics – 9 Year Follow Up

    P. Witkowski, M. Garfinkel, L. Schenck, S. Pannain, J. Thistlethwaite, W. Chon, O. Cochet, K. Golab, O. Savari, J. Millis

    Surgery, Medicine, University of Chicago, Chicago, IL; Surgery, Southern Illinois University School of Medicine, Springfield, IL

    The aim of the study was to assess long-term outcomes of the pancreatic islet transplantation. Methods: Human pancreatic islets were administered sequentially in up to…
  • 2013 American Transplant Congress

    Incidence, Risk Factors, and Response Rate to Initial Therapy for Clostridum Difficile in Solid Organ Transplant Recipients

    M. Wheeler, J. Deyo, J. Huang, R. Lee, T. Kozlowski, R. Dupuis

    University of North Carolina, Chapel Hill, NC

    Clostridium difficile Infection (CDI) has been shown to occur at a higher rate in the solid organ transplant (SOT) population compared to the general hospitalized…
  • 2013 American Transplant Congress

    Gelatinase-A Inhibition Upregulates Gelatinase-B Activity and Exacerbates Hepatic Ischemia and Reperfusion Injury

    H. Kato, S. Duarte, D. Liu, R. Busuttil, A. Coito

    The Dumont-UCLA Transplant Center, Los Angeles, CA

    Hepatic ischemia/reperfusion injury (IRI) linked to leukocyte recruitment has a negative impact on graft outcomes. Focal matrix degradation is a key prerequisite for leukocyte transmigration…
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