ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Immunosuppressive Property of Liver Sinusoidal Endothelial Cells Is Impaired in Small-for-Size Grafts and Restored by Attenuating Portal Hypertension, The

    S. Hashimoto, T. Onoe, Y. Tanaka, Y. Igarashi, H. Ohdan

    Department of Surgery, Hiroshima University, hiroshima, Japan

    Background:We have previously shown that the accelerated anti-donor immune response is related to the portal hypertension (PH) that develops after living-donor liver transplantation (LDLT), especially…
  • 2013 American Transplant Congress

    Telaprevir Based Combination Therapy for the Treatment of Recurrent HCV in Liver Transplant Recipients: Promising Early Results, Late Disappointment

    B. Gelb, R. Layman, L. Teperman

    Department of Surgery, Division of Transplant Surgery, NYU Langone Medical Center, New York, NY

    Background:HCV recurrence is virtually universal in viremic patients at the time of transplant. Long term patient and graft survival is inferior in HCV patients unless…
  • 2013 American Transplant Congress

    Follow-Up Reporting for Living Kidney Donors

    J. Wainright, M. McBride, M. Dew, D. Bolton, C. Thomas

    UNOS, Richmond, VA; U of Pittsburgh, Pittsburgh, PA; U of Iowa, Iowa City, IA

    Follow-up reporting for living kidney donors (LKDs) increases knowledge of short-term risks of donation. Anecdotal evidence suggests that low reporting rates are due to LKDs…
  • 2013 American Transplant Congress

    miRNA Signature Associated with Induced Tolerance in Liver Allografts, The

    L. Wei, K. Ruster, C. Esquivel, O. Martinez, S. Krams

    Department of Surgery/Division of Abdominal Transplantation, Stanford University, Stanford, CA

    Although the liver is less immunogenic than other solid organs, most liver transplant recipients receive lifelong immunosuppression. A subset of liver recipients may be operationally…
  • 2013 American Transplant Congress

    Enhanced Liver Regeneration in Mice Lacking the Chemokine Receptor CCR5

    C. Gonelle-Gispert, S. Sorce, P. Morel, R. Meier, S. Lacotte, D. Bosco, L. Buhler

    Surgical Research Unit, University of Geneva, Medical School, Geneva, Switzerland; Pathology and Immunology, University of Geneva, Medical School, Geneva, Switzerland; Surgical Research Unit, University Hospitals of Geneva, Geneva, Switzerland; Surgical Research Unit, University of Geneva, Medical School, Geneva, Switzerland; Surgical Research Unit, University of Geneva, Medical School, Geneva, Switzerland; Surgical Research Unit, University of Geneva, Medical School, Geneva, Switzerland; Surgical Research Unit, University of Geneva, Medical School, Geneva, Switzerland

    Introduction: Further knowledge of basic mechanisms that regulate liver regeneration may help to find therapies to increase otherwise insufficient liver mass. The chemokine receptor CCR5…
  • 2013 American Transplant Congress

    Influence of Organ Retrieval Team on Mid-Term Outcome of Lung Transplantation

    D. García Sáez, A. Sabashnikov, B. Zych, P. Mohite, A. Moza, F. De Robertis, T. Bahrami, M. Amrani, M. Carby, A. Reed, A. Simon

    Department of Cardiothoracic Transplantation & Mechanical Support, Royal Brompton and Harefield NHS Trust, Harefield Hospital, London, United Kingdom

    Purpose Due to a zonal organ allocation scheme introduced in United Kingdom, organ retrieval is performed frequently by different centers. This study evaluates the influence…
  • 2013 American Transplant Congress

    Effect of Induction Therapy with Thymoglobulin on Outcome in Hepatitis C Infected Kidney Transplant Recipients: A Single Center Experience

    J. Linatoc, Q. Ren, M. Behnke, M. Posner, A. King

    Virginia Commonwealth University, Richmond

    This study evaluated the impact of induction therapy with thymoglobulin (ATG) on outcome in hepatitis C virus positive (HCV+) kidney transplant recipients.We retrospectively studied 79…
  • 2013 American Transplant Congress

    Utility of Serum Markers in Evaluating Graft Pancreatitis Following Simultaneous Pancreas-Kidney Transplantation

    M. Chhabra, F. Powell, N. Hillard, J. Bradley, C. Watson, A. Shaw, G. Pettigrew, S. Harper

    Department of Surgery, University of Cambridge, Cambridge, United Kingdom; Department of Radiology, Addenbrooke's Hospital, Cambridge, United Kingdom

    INTRODUCTION. Graft pancreatitis remains difficult to diagnose using clinical assessment alone, leading to indiscriminate use of cross-sectional imaging. We seek to correlate the presence of…
  • 2013 American Transplant Congress

    PI3Kδ Inhibition Augments the Efficacy of mTOR Inhibitor Rapamycin on the Proliferation of Epstein-Barr Virus (EBV)+ B Cell Lymphomas

    S. Furukawa, O. Hatton, S. Krams, C. Esquivel, O. Martinez

    Department of Surgery, Stanford University School of Medicine, Stanford, CA

    Post-transplant lymphoproliferative disorder (PTLD) is a devastating and potentially life-threatening complication in transplant recipients. PTLD is associated with EBV infection and can result in malignant…
  • 2013 American Transplant Congress

    Identification of EBV-Specific CXCR3+/CXCR5+ CD8+T Cells in Peripheral Blood of Asymptomatic Pediatric Heart Transplant Recipients Who Carry EBV Loads

    C. Macedo, T. Shipley, K. Hadi, A. Norlander, J. Luce, B. Feingold, S. Webber, D. Metes

    Surgery, Thomas E. Starzl Transplantation Institute, Pittsburgh; Cardiology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh; Immunology, University of Pittsburgh, Pittsburgh

    Unlike immunocompetent healthy subjects who carry EBV infection in a latent form, approximately 70% of EBV asymptomatic immunosuppressed pediatric heart transplant (HTx) recipients carry chronic…
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