2013 American Transplant Congress
Subclinical Recurrent Lupus Nephritis: A Clinicopathologic Study
BackgroundThe frequency and significance of recurrent lupus nephritis (LN) is unclear. We evaluated the features of subclinical recurrent LN seen on early posttransplant biopsies and…2013 American Transplant Congress
Safety and Effectiveness of Valganciclovir for Cytomegalovirus Prophylaxis in Solid Organ Transplant Patients on Hemodialysis
Purpose: Valganciclovir is used for the prevention of cytomegalovirus (CMV) infections in solid organ transplant (SOT) patients. Currently, no dosing recommendation is available for patients…2013 American Transplant Congress
True MELD Score Is Associated with HCC Patient Outcomes after Liver Transplant
Introduction:Patients with in-criteria HCC listed for liver transplantation(OLT) receive exception MELD scores(EM) not adjusted for disease severity unless the calculated, true MELD score(TM) exceeds the…2013 American Transplant Congress
DAP12 Deficiency in Liver Allografts Enhances Donor DC Migration, Host Alloimmunity and Breaks Liver Transplant Tolerance
Background: Fully MHC-mismatched mouse liver allografts are accepted without immunosuppressive therapy and induce donor-specific tolerance. Liver dendritic cells (DC) exhibit an immature phenotype that may…2013 American Transplant Congress
Role of Innate and Adaptive Immunity in Survival and Neurogenesis of Neural Progenitor Cell Grafts, The
Surgery, Stanford University SOM, Stanford, CA; Neurosurgery, Stanford University SOM, Stanford, CA
Neural Progenitor Cells (NPC) are multipotent progenitors found within the brain that differentiate into neurons, oligodendrocytes, and astrocytes. Transplantation of NPC has been proposed as…2013 American Transplant Congress
Telomere Length of Living Kidney Donors and Recipients and Chronic Graft Dysfunction in Kidney Transplants
University of Minnesota, Minneapolis, MN
Background: Telomeres consist of multiple copies (100s to 1000s) of short (6 nucleotide) repeats at the end of all chromosomes, playing a protective role against…2013 American Transplant Congress
Time on Waiting List for Patients with High MELD Does Not Influence Graft or Patient Survival after Liver Transplantation
Northwestern University, Chicago
BACKGROUND: With the decreased donor availability, even patients with high MELD scores can have prolonged wait times for liver transplantation (LT). However, it is unknown…2013 American Transplant Congress
Injected Allogeneic CD4+CD25+ Tregs Regulate the Neonatal Immune System and Prolong Heart Allograft Survival
University of Alberta, Edmonton, Canada
Introduction/Methods: Semi-allogeneic (F1; H-2k/b) splenocytes (SC) injected into newborn mice (H-2k) induce immunological tolerance whereas allogeneic SC (H-2b) lead to graft-vs-host disease (GVHD). Here we…2013 American Transplant Congress
Obesity Negatively Impacts Access to Transplantation in Women but Not Men
Nephrology, University of British Columbia, Vancouver, Canada
It is known that obese wait-listed patients are less likely to undergo deceased donor transplantation compared to non-obese patients. Using Cox multivariate regression analyses and…2013 American Transplant Congress
Mismatched VCA Transplantation without the Need for Donor Cell Chimerism: A Model To Achieve Tolerance While Eliminating Chronic Immunosuppression and the Risks of GVHD
Introduction: The application of Vascularized Composite Allograft (VCA) transplantation is limited by the need for immunosuppression. Tolerance induction protocols using stem cell transplantation can eliminate…
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