ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Clinical Outcomes of Paired Kidney Exchange for Highly Sensitized Renal Transplant Recipients

    M. Grafals, M. Cooper, J. Verbesey, J. Vucci, B. Javaid, O. Timofeeva, S. Rosen-Bronson

    Georgetown Transplant Institute, Georgetown University Hospital, Washington, DC; Histocompatibility Laboratory, Georgetown University Hospital, Washington, DC

    Purpose: A local multicenter paired kidney exchange (PKE) was employed to facilitate identification of compatible donors for highly-sensitized recipients.Methods: Virtual crossmatching was used to identify…
  • 2013 American Transplant Congress

    Effect of Donor Comorbidites on Patient Survival – Standard Criteria Donor Kidney Compared to Expanded Criteria Donor Kidney Transplantation

    A. Patel, L. Malinzak, M. Goggins, V. Karthikeyan, K. Venkat, M. Abouljoud

    The Transplant Institute, Henry Ford Hospital, Detroit, MI

    Most studies of Expanded Criteria Donor (ECD) kidney (K) transplantation confirm that recipients(R) of ECD K have improved survival compared with matched dialysis-treated patients. However,…
  • 2013 American Transplant Congress

    Is the Obesity Epidemic in the United States Driving the Lack of Growth of Live Kidney Donation?

    D. Moore, I. Feurer, L. Dageforde, E. Zavala, D. Moore

    Division of Kidney/Pancreas Transplantation, Vanderbilt University Medical Center, Nashville, TN

    Introduction: The prevalence of obesity in the United States has increased significantly over the last twenty years and nearly one-third of adults are obese. The…
  • 2013 American Transplant Congress

    Donor Brain Death Results in Differentially Modulated Immune Activation in Solid Organs

    P. Ritschl, R. Oberhuber, C. Fabritius, S. Ebner, B. Flörchinger, J. Guenther, A. Nguyen, J. Pratschke, K. Kotsch

    Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria; Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany

    Donor brain death (BD) and its pathophysiological changes have been shown to influence graft quality, therefore accelerating the immune response post transplantation. However, detailed information…
  • 2013 American Transplant Congress

    Predictors of Clostridium Difficile Infection in Liver Transplant Recipients: A 10 Year Single-Center Cohort Study

    C. Mittal, S. Arshad, M. Miceli, I. Bajjoka, L. Brown, M. Abouljoud, M. Ramesh, G. Alangaden

    Transplant Institute, Henry Ford Hospital, Detroit, MI

    Background: Clostridium difficile infection (CDI) is a common cause of morbidity and is associated with increased in-hospital mortality among solid organ transplant recipients. The incidence…
  • 2013 American Transplant Congress

    Prolonged Cold Ischemia Impairs Outcome in Recipients of Donation after Cardiac Death (DCD) Kidney Transplants Despite Machine Perfusion

    S. Paloyo, J. Sageshima, G. Ciancio, L. Chen, A. Mattiazzi, G. Guerra, W. Kupin, D. Roth, S. Ganz, G. Burke III

    Miami Transplant Institute, University of Miami Miller School of Medicine, Miami

    Introduction: The impact of prolonged cold ischemia time (CIT) on kidney grafts donated after circulatory death (DCD) remains unclear when grafts were preserved by hypothermic…
  • 2013 American Transplant Congress

    Challenges in Safety Managing the Pain in Living Liver Donors

    D. Ladner, K. Waitzman, T. Strenski, E. Pomfret, M. Simpson, R. Brown, R. Fisher, R. Kang, T. Berzins, A. Daud, J. Holl, D. Woods

    Northwestern University, Chicago; Lahey Clinic, Boston; Columbia University, New York; Virginia Commonwealth University, Richmond

    BACKGROUND: Living Liver Donation (LD) is a highly complex major surgical procedure associated with pain. However, managing pain after LD is difficult, as opioid pharmacokinetics…
  • 2013 American Transplant Congress

    Esophageal Eosinophilia after Intestinal Transplantation

    K. Khan, C. Desai, R. Girlanda, E. Island, C. Matsumoto, T. Fishbein, S. Kaufman

    Transplantation, MedStar Gerogetown University Hospital, Washington, DC

    Background: The prevalence of eosinophilic esophagitis (EoE) has been increasing, with estimates up to 0.1% of children. We examined esophageal eosinophilia in children after intestinal…
  • 2013 American Transplant Congress

    Human Regulatory B Cells (BRegs) Are Characterised by Both IL-10 and TNF-α Expression and Are Reduced in Numbers with Altered Function in Renal Transplant Recipients with Immunological Graft Injury

    A. Cherukuri, A. Salama, C. Carter, B. Clark, D. Rothstein, R. Baker

    St.James's University Hospital, Leeds, United Kingdom; UCL, London, United Kingdom; UPMC, Pittsburgh

    Human Bregs are defined by their ability to express IL-10 and suppress T cells in vitro. We noted that putative Breg subsets also produce pro-inflammatory…
  • 2013 American Transplant Congress

    Anti-CD3 Accelerated Diabetes in Transgenic Non-Obese Diabetic (NOD) Mice Expressing miRNA Decoy Sequence(s)

    O. Pankewycz, J. Xuan, L. Shen, J. Ambrus, Jr, M. Laftavi

    Medicine, SUNY at Buffalo; Surgery, SUNY, University at Buffalo, Buffalo, NY

    Microinhibitory RNAs (miRNAs) are short sequences that regulate post-transcriptional mRNA and protein expression. miRNA decoy genes alter gene expression by interfering with miRNA binding to…
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